What is Sertraline?

Category: Prescription Drugs

Most popular types: Zoloft Apo-Sertraline Lustral Show all

false

Sertraline, a selective serotonin reuptake inhibitor (SSRI) antidepressant, is used in the treatment of major depression, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and social anxiety disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 1,725 839
Major Depressive Disorder 1,467 791
Post-traumatic Stress Disorder 661 387
Anxious mood 481 206
Panic Disorder 298 179
Persistent depressive disorder (dysthymia) 202 149

Show all 210 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 236
Moderate 421
Mild 484
None 755

Commonly reported side effects and conditions associated with Sertraline

Side effect Patients
Weight gain 117
Dry mouth 78
Sex drive (libido) decreased 73
Loss of sex drive (libido) 67
Fatigue 64
Insomnia 43

Show all 370 reported side effects

Dosages

Based on patients currently taking Sertraline

Dosage Patients
100 mg daily 193
50 mg daily 146
200 mg daily 90
150 mg daily 83
25 mg daily 57
100 mg twice daily 25
75 mg daily 11
50 mg twice daily 11
20 mg daily 4
200 mg twice daily 4

See all 39 dosages

Why patients stopped taking Sertraline

Multiple reasons could be selected

Reason Patients
Did not seem to work 694
Side effects too severe 459
Doctor's advice 397
Other 268
Course of treatment ended 86
Personal research 80
Expense 59
Change in health plan coverage 45
See all 1467 patients who’ve stopped taking Sertraline

Duration

Currently taking Sertraline

Duration Patients
Less than 1 month 4
1 - 6 months 62
6 months - 1 year 94
1 - 2 years 97
2 - 5 years 153
5 - 10 years 130
10 years or more 125

Stopped taking Sertraline

Duration Patients
Less than 1 month 239
1 - 6 months 314
6 months - 1 year 236
1 - 2 years 219
2 - 5 years 253
5 - 10 years 133
10 years or more 84
Adherence
Adherence Evaluations
Always 1482
Usually 277
Sometimes 67
Never taken as prescribed 70
Burden
Burden Evaluations
Very hard to take 79
Somewhat hard to take 128
A little hard to take 284
Not at all hard to take 1405
Cost per month
Cost per month Evaluations
$200+ 8
$100-199 19
$50-99 18
$25-49 75
< $25 957
Not specified 819

What people switch to and from

Patients started taking Sertraline after stopping:

Treatment Patients
Fluoxetine (Prozac) 79
Citalopram (Celexa) 66
Bupropion (Wellbutrin XL) 43
Venlafaxine (Effexor XR) 34
Duloxetine (Cymbalta) 31

Show all 52 treatments patients report switching from

Patients stopped taking Sertraline and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 58
Duloxetine (Cymbalta) 50
Bupropion (Wellbutrin XL) 48
Fluoxetine (Prozac) 42
Escitalopram (Lexapro) 37

Show all 42 treatments patients report switching to

Last updated:

146 patient evaluations for Sertraline

1,472 members have decided to share their profiles only with other members of PatientsLikeMe.

MSMomx4
Portrait default thumb
MSMomx4
Sex: F
Data Quality: 2 stars
Sensation: Mild
Overall: Mild
Cognition: moderate
Vision: mild
Speech: mild
Swallowing: mild
Upper limb: mild
Walking: moderate
I am: g
I have:
MS

See MSMomx4's full Sertraline history

Feb 15, 2017 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: No changes
Cost: < $25 monthly

Nov 30, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: No changes since 3/20/15
Cost: < $25 monthly

Aug 2, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

May 9, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Apr 24, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 1, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Oct 21, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 20, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: My digestive problems have been resolved. I have no other conditions that would lead a doctor to think I had anything seriously wrong with me. I now take 150 mgs of Zoloft. I take it every day with no problem.
Cost: < $25 monthly

Feb 4, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: The only problem I've had is bad diarhea, from starting to take it again after not having been on it for about a month. This was due to a change in providers.
Cost: < $25 monthly

Oct 28, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Sep 10, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: I am now taking 200 mg a day (4 50mg tabs a day). I have no problems with taking it at all.
Cost: < $25 monthly

Jun 2, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

May 8, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Jan 17, 2011 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: it has had no impact on my lifestyle at all. It is a pill taken once a day.
Cost: < $25 monthly

  • 0 helpful marks
leejon66
67203 thumb
leejon66
Gender: M
Data Quality: 3 stars
Depression: 0
Mania: 0
Emotional: 1
Anxiety: 2
Compulsion: 0
External Stress: Low
68 M
Function: High
Distress: Low
I am: n
I have:
PTSD

See leejon66's full Sertraline history

Feb 12, 2017 (Started Jul 01, 1982)

  • Effectiveness
    None (for Post-traumatic Stress Disorder)
  • Effectiveness
    None (for Panic Disorder)
  • Effectiveness
    None (for Major Depressive Disorder)
  • Effectiveness
    None (for Depressed mood)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Somewhat hard to take
Dosage: Yearly
Cost: < $25 monthly

  • 0 helpful marks
mrsnurse
53908 thumb
mrsnurse
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: None
Cognition: moderate
Vision: none
Speech: none
Swallowing: none
Upper limb: moderate
Walking: none
I am: g
I have:
MS

See mrsnurse's full Sertraline history

Feb 12, 2017 (Started Aug 14, 1993)

  • Effectiveness
    Moderate (for Emotional lability)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I always take this treatment because MS can actually cause depresion, and since the MS has caused me to lose so much in my life, I know without a doubt I must take this!!

  • 0 helpful marks
Last updated:
Showing 3 of 146 patient evaluations for Sertraline