• Effectiveness

  Major (for Parkinson's disease)
• Side effects

  Mild (for Overall)
• Adherence

  Always
• Burden

  A little hard to take

Advice & Tips: When taken alone, one dose lasts about an hour or so. When taken with Comtan, "ON" period is extended up to 2 - 2.5 hours. Needs to be taken on empty stomach. Proteins, fats, or a full stomach (even a moderately full feeling) disrupts effectiveness. Rate if absorption is decreased with presence of food in stomach or "ON" period is prevented altogether. Usually takes 40-50 minutes for a dose to kick in. Can be speeded up by disolving tablet in water first or by taking with a cola beverage. Unexpected benefits are when I am "ON", others have a hard time keeping up with me.