What is Dimethyl fumarate?

Category: Prescription Drugs

Most popular types: Tecfidera

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Dimethyl fumarate is primarily used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 1026 887
Participate in clinical trial 10 11
Psoriasis 2 2
Arthritis pain 1 0
Brain atrophy cerebrum 1 0

Show all 15 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 140
Moderate 165
Mild 368
None 225

Commonly reported side effects and conditions associated with Dimethyl fumarate

Side effect Patients
Flushing 200
Facial flushing 62
Nausea 55
Diarrhea 54
Stomach pain 44
Itching 30

Show all 199 reported side effects

Dosages

Based on patients currently taking Dimethyl fumarate

Dosage Patients
240 mg twice daily 92
120 mg twice daily 27
480 mg daily 23
240 mg daily 14
120 mg daily 12
1 capsule(s) twice daily 4
2 capsule(s) twice daily 4
480 mg twice daily 4
daily 3
1 capsule(s) daily 2

See all 38 dosages

Why patients stopped taking Dimethyl fumarate

Multiple reasons could be selected

Reason Patients
Side effects too severe 166
Doctor's advice 97
Did not seem to work 78
Other 46
Course of treatment ended 10
Personal research 10
Expense 7
Change in health plan coverage 6
See all 316 patients who've stopped taking Dimethyl fumarate

Duration

Currently taking Dimethyl fumarate

Duration Patients
1 - 6 months 6
6 months - 1 year 8
1 - 2 years 29
2 - 5 years 128
5 - 10 years 54

Stopped taking Dimethyl fumarate

Duration Patients
Less than 1 month 63
1 - 6 months 73
6 months - 1 year 58
1 - 2 years 62
2 - 5 years 60
5 - 10 years 1
10 years or more 1
Adherence
Adherence Evaluations
Always 717
Usually 119
Sometimes 14
Never taken as prescribed 48
Burden
Burden Evaluations
Very hard to take 45
Somewhat hard to take 61
A little hard to take 128
Not at all hard to take 664
Cost per month
Cost per month Evaluations
$200+ 29
$100-199 7
$50-99 27
$25-49 57
< $25 456
Not specified 322

What people switch to and from

Patients started taking Dimethyl fumarate after stopping:

Treatment Patients
Glatiramer acetate (Copaxone) 123
Interferon beta-1a IM Injection (Avonex) 60
Interferon beta-1a SubQ injection (Rebif) 55
Natalizumab (Tysabri) 49
Fingolimod (Gilenya) 29

Show all 20 treatments patients report switching from

Patients stopped taking Dimethyl fumarate and switched to:

Treatment Patients
Teriflunomide (Aubagio) 45
Glatiramer acetate (Copaxone) 39
Natalizumab (Tysabri) 30
Fingolimod (Gilenya) 26
Ocrelizumab (Ocrevus) 19

Show all 18 treatments patients report switching to

Last updated:

37 patient evaluations for Dimethyl fumarate

Dec 15, 2017 (Started May 16, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Severe (increased indexes for PML.)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Advice & Tips: when I had been taking Tecfidera, I had taken a low-dose aspirin a few minutes before swallowing the capsule. The low-dose aspirin relieved the flushing feeling on my face and neck.
Cost: < $25 monthly

Sep 15, 2017 (Started May 16, 2013)

  • Effectiveness
    None (for multiple sclerosis)
  • Side effects
    Severe (increased indexes for PML.)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Cost: < $25 monthly

  • 1 helpful mark

Aug 2, 2017 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Cost: < $25 monthly

Mar 16, 2017 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 28, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Mar 10, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Mild (stomach pain, flushing)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Dec 11, 2015 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    Mild (stomach pain, flushing)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Sep 27, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 22, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily

  • 2 helpful marks

Jul 29, 2017 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Moderate (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: i've reduced my dosage to 240 mg(half), because having only a 300 cell margin is simply too small.
Cost: < $25 monthly

Sep 30, 2016 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: my jc virus level is just slightly greater, so I'll continue with it.
Cost: < $25 monthly

Jan 25, 2016 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Moderate (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I feel my JC virus titer level is high at 2.14, but there is presently no other drug with a safer side-effect profile, so I'm waiting for the next approved MS medication to switch to:-(
Cost: < $25 monthly

Feb 26, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: Tuesday's MRI is clear (no new or active lesions), so will continue with this medication.
Cost: < $25 monthly

Jan 14, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I must eat a meal with meat or I'll throw-up.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 37 patient evaluations for Dimethyl fumarate