Hereditary spastic paraplegia

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What is hereditary spastic paraplegia?

Hereditary Spastic Paraplegia is not a single disease but a group of genetic disorders in which the main feature is progressive spasticity in the lower limbs due to pyramidal tract dysfunction. Onset can be at any age, from the first year of life to old age, depending on the specific genetic form.

Common symptoms reported by people with hereditary spastic paraplegia

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
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Treatments taken by people for hereditary spastic paraplegia

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Mylan-Baclofen)
Type
Prescription Drug
How many have tried
144
Treatment name(s)

(Zanaflex)
Type
Prescription Drug
How many have tried
38

Data from patients with hereditary spastic paraplegia, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
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Compare treatments taken by people with hereditary spastic paraplegia

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Mylan-Baclofen)
Perceived effectiveness
for hereditary spastic paraplegia (1 evaluation)
Side effects
drowsiness
Total evaluations
1
Treatment name(s)

(Zanaflex)
Perceived effectiveness
for hereditary spastic paraplegia (1 evaluation)
Side effects
Total evaluations
1
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with hereditary spastic paraplegia, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
Last updated:

Who has hereditary spastic paraplegia on PatientsLikeMe?

  • 0 new patients joined this month
  • 227 say hereditary spastic paraplegia is their primary condition

Age
Age Proportion # of patients
<20 6
20s 16
30s 31
40s 42
50s 68
60s 46
70+ 28
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 28
20-29 years 13
30-39 years 18
40-49 years 19
50-59 years 14
60-69 years 1
70+ years 0

Distribution of sex

Sex
Sex Proportion # of patients
Male 96
Female 148

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 97
Not Diagnosed 13

These charts show data from hereditary spastic paraplegia patients who have completed their condition history
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