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Home > Community Treatment Reports > Modafinil Treatment Report
What is Modafinil?

Modafinil is stimulant used to improve wakefulness in patients narcolepsy and shift work sleep disorder; adjunctive therapy for obstructive sleep apnea. Off label it is used for attention-deficit/hyperactivity disorder and to treat fatigue in MS and other disorders.

Reasons taken & Efficacy

Reasons and Efficacy
Reasons taken
# of patients Efficacy
Major
Moderate
Slight
None
Can’t tell
# of patients evaluated by
Fatigue 1196 280
Excessive daytime sleepiness (somnolence) 282 99
Brain fog 72 21
Multiple Sclerosis MS 58 8
Other 51 11
Cognitive impairment 32 10

See all 1427 patients currently taking Modafinil

Mouse over the table for more information

Side Effects

Side effects as an overall problem

Severe
18
Moderate
51
Mild
99
None
213

Most commonly reported side effects

Jittery feeling
47
Dry mouth (xerostomia)
44
Headaches
33
Sleep problems
30
Anxiety
29
Heart rate increased
26
  • Mild
  • Moderate
  • Severe

Dosages

Top 10 dosages based on patients currently taking Modafinil. See all 46 dosages

  0.5 100mg as needed 0.5 200mg as needed 0other as needed 100 mg as needed 100mg as needed 10mg as needed 150mg as needed 1.5 100mg as needed 1mg as needed 200 mg as needed 200mg as needed 2 100mg as needed 2 200mg daily 300mg as needed 400mg as needed 50mg as needed as needed daily mg as needed 1 daily 1 mcg daily 1 other daily 2 mg daily 3 mg daily 5 mg daily 100 mg weekly 20 mg daily 25 mg daily 40 mg daily 50 daily 50 mg daily 70 mg daily 100 daily 100 mg daily 100 mg one time 150 mg daily 200 daily 200 mg daily 250 mg daily 300 mg daily 400 mg daily 500 mg daily 600 mg daily 800 mg daily 800 tbs. daily 1200 mg daily
  2 Number of Patients: 2 2 Number of Patients: 2 1 Number of Patients: 1 5 Number of Patients: 5 66 Number of Patients: 66 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 3 Number of Patients: 3 52 Number of Patients: 52 11 Number of Patients: 11 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 9 Number of Patients: 9 5 Number of Patients: 5 22 Number of Patients: 22 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 16 Number of Patients: 16 1 Number of Patients: 1 1 Number of Patients: 1 325 Number of Patients: 325 1 Number of Patients: 1 5 Number of Patients: 5 2 Number of Patients: 2 611 Number of Patients: 611 2 Number of Patients: 2 34 Number of Patients: 34 225 Number of Patients: 225 2 Number of Patients: 2 7 Number of Patients: 7 5 Number of Patients: 5 1 Number of Patients: 1 1 Number of Patients: 1  

Stop Reasons

Why Patients Stopped Taking Modafinil (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work
119   Did not seem to work: 31%
Other
98   Other: 25%
Expense
86   Expense: 22%
Side effects too severe
81   Side effects too severe: 21%
Doctor's advice
60   Doctor's advice: 16%
Change in health plan coverage
25   Change in health plan coverage: 6%
Personal research
17   Personal research: 4%
Course of treatment ended
9   Course of treatment ended: 2%
Not indicated
3   Not indicated: 1%

See all 381 patients who’ve stopped taking Modafinil

Currently Taking Modafinil

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Modafinil

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Always
240 63%
Usually
90 24%
Sometimes
44 12%
Never
7 2%

Burden

Difficulty being on treatment

Very
15 4%
Somewhat
31 8%
A little
59 15%
Not at all
276 72%

Cost

Paid out of pocket

$200+
23 6%
$100-199
15 4%
$50-99
67 18%
$25-49
74 19%
< $25
100 26%

See more information, including instructions, precautions, side effects, and interactions.

Report created on September 09, 2010.