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What is Lamivudine-Zidovudine?

The combination of lamivudine (Epivir) and zidovudine (AZT, ZDP) is used to treat HIV in patients with or without acquired immunodeficiency syndrome (AIDS). Lamivudine and zidovudine are in a class of antiviral medications called synthetic nucleoside analogues.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
HIV (Human Immunodeficiency Virus) 58 17 Efficacy_major Efficacy_moderate Efficacy_cant_tell
Other 5 1 Efficacy_major
Support immune health 2 0
low CD4 1 1 Efficacy_moderate
Pregnancy 1 1 Efficacy_cant_tell
Depressed mood 1 0

See all 58 patients currently taking Lamivudine-Zidovudine

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Reported Side Effects

Side effects as an overall problem

Severe
 1
Moderate
 4
Mild
 8
None
 7

Commonly reported side effects, conditions, and hospitalizations associated with Lamivudine-Zidovudine

Diarrhea 8
Nausea 5
Fatigue 5
Lethargy 3
Tiredness 2
Mean corpuscular volume elevated 1
See all 11 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Lamivudine-Zidovudine. See all 11 dosages ►

  daily 200 tbs. monthly 12 hr daily 150 mg daily 200 mg daily 300 g daily 300 mg daily 150 mg-300 mg daily 2 x 150 mg-300 mg daily 4 x 150 mg-300 mg daily
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 6 Number of Patients: 6 5 Number of Patients: 5 33 Number of Patients: 33 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Taking Lamivudine-Zidovudine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Doctor's advice 13   Doctor's advice: 41%
Other 9   Other: 28%
Side effects too severe 7   Side effects too severe: 22%
Personal research 5   Personal research: 16%
Course of treatment ended 4   Course of treatment ended: 13%
Not indicated 3   Not indicated: 9%
Expense 1   Expense: 3%
Change in health plan coverage 1   Change in health plan coverage: 3%
Did not seem to work 1   Did not seem to work: 3%

See all 32 patients who’ve stopped taking Lamivudine-Zidovudine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Lamivudine-Zidovudine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0

Stopped Taking Lamivudine-Zidovudine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Lamivudine-Zidovudine

Always
 18 90%
Usually
 2 10%
Sometimes
 0 0%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Lamivudine-Zidovudine

Very
 2 10%
Somewhat
 2 10%
A little
 5 25%
Not at all
 11 55%

Cost

Paid out of pocket

Cost of Lamivudine-Zidovudine

$200+
 1 7%
$100-199
 1 7%
$50-99
 0 0%
$25-49
 2 14%
< $25
 8 57%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 28, 2012.