What is naltrexone?

Naltrexone oral is an special narcotic drug that blocks the effects of other narcotic medicines and alcohol.

Naltrexone oral is used to treat narcotic drug or alcohol addiction..

Naltrexone oral may also be used for other purposes not listed in this medication guide.

Precautions

Do not take this medicine if you are allergic to naltrexone, or if you have:

  • an addiction to narcotics;
  • a history of alcohol or narcotic drug use within the past 7-10 days; or
  • drug or alcohol withdrawal symptoms.

Before taking naltrexone, tell your doctor if you are allergic to any drugs, or if you have:

  • kidney disease;
  • liver disease; or
  • a bleeding disorder such as hemophilia (if you are using naltrexone oral injection).

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether naltrexone oral passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Naltrexone oral can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Do not use narcotic drugs or alcohol while taking naltrexone oral. Never try to overcome the effects of the medication by taking large doses of narcotic drugs or alcohol. Doing so could result in dangerous effects, including coma and death. Ask your doctor before using any prescription or over-the-counter medicine to treat a cold, cough, diarrhea, or pain while taking naltrexone oral. These medicines may contain narcotics or alcohol.

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Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, stomach pain, dizziness, or seizure (convulsions).

Take the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not take extra medicine to make up the missed dose.

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Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using naltrexone oral and call your doctor at once if you have any of these serious side effects:

  • blurred vision or eye problems;
  • fast heartbeat;
  • mood changes, hallucinations (seeing or hearing things), confusion, thoughts of hurting yourself;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • ear pain, ringing in your ears;
  • skin rash or itching; or
  • wheezing, difficulty breathing.

Less serious side effects may include:

  • feeling anxious, nervous, restless, or irritable;
  • feeling light-headed, fainting;
  • increased thirst;
  • muscle or joint aches;
  • weakness or tiredness;
  • sleep problems (insomnia); or
  • decreased sex drive, impotence, or difficulty having an orgasm.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

The pain-relieving effects of any narcotic pain medications you use will be blocked if you use them during your treatment with naltrexone oral. Harmful side effects could also occur.

Before using naltrexone, tell your doctor if you use any of the following drugs:

  • buprenorphine (Buprenex, Subutex);
  • butorphanol (Stadol);
  • codeine (Tylenol with codeine);
  • hydrocodone (Lortab, Vicodin);
  • dezocine (Dalgan);
  • hydromorphone (Dilaudid);
  • levorphanol (Levo-Dromoran);
  • meperidine (Demerol);
  • methadone (Dolophine, Methadose);
  • morphine (Kadian, MS Contin, Roxanol);
  • nalbuphine (Nubain);
  • nalmefene (Revex);
  • naloxone (Narcan);
  • oxycodone (OxyContin, Roxicodone, Percocet);
  • oxymorphone (Numorphan); or
  • propoxyphene (Darvon, Darvocet).

This list it not complete and there may be other drugs that can interact with naltrexone oral. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Other Names

ReVia, Vivitrol, and naltrexone

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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