Levetiracetam Treatment Report

Category: Prescription Drugs

Most Popular Types: Keppra, Keppra XR

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Generic Name: Levetiracetam

What is Levetiracetam?

An example of Levetiracetam

Levetiracetam is is an anticonvulsant used in combination with other medications to treat partial onset, myoclonic, and/or primary generalized tonic-clonic seizures.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
1,068 406 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
86 23 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
68 33 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
38 17 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
18 3 Efficacy_moderate Efficacy_slight Efficacy_cant_tell
13 1 Efficacy_slight

See all 1,194 patients currently taking Levetiracetam

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Reported Side Effects

Side effects as an overall problem

Severe
88
Moderate
153
Mild
143
None
100

Commonly reported side effects, conditions, and hospitalizations associated with Levetiracetam

37
26
26
22
21
21
See all 267 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Levetiracetam. See all 74 dosages

  250 mg daily 500 mg daily 750 mg daily 1,000 mg daily 1,500 mg daily 2,000 mg daily 2,250 mg daily 2,500 mg daily 3,000 mg daily 4,000 mg daily
  29 Number of Patients: 29 130 Number of Patients: 130 32 Number of Patients: 32 264 Number of Patients: 264 171 Number of Patients: 171 195 Number of Patients: 195 17 Number of Patients: 17 44 Number of Patients: 44 210 Number of Patients: 210 48 Number of Patients: 48  

Reported Stop Reasons

Why Patients Stopped Taking Levetiracetam (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 148   Side effects too severe: 49%
Did not seem to work 112   Did not seem to work: 37%
Doctor's advice 89   Doctor's advice: 30%
Other 29   Other: 10%
Expense 20   Expense: 7%
Course of treatment ended 14   Course of treatment ended: 5%
Personal research 13   Personal research: 4%
Not indicated 7   Not indicated: 2%
Change in health plan coverage 5   Change in health plan coverage: 2%

See all 291 patients who’ve stopped taking Levetiracetam

Currently Taking Levetiracetam

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Levetiracetam

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Levetiracetam

Always
426 88%
Usually
41 8%
Sometimes
5 1%
Never
12 2%

Burden

Difficulty being on treatment

Burden of Levetiracetam

Very
30 6%
Somewhat
46 10%
A little
77 16%
Not at all
331 68%

Cost

Paid out of pocket

Cost of Levetiracetam

$200+
22 7%
$100-199
15 5%
$50-99
39 13%
$25-49
38 13%
< $25
188 62%

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86 patient evaluations for Levetiracetam

Purpose: Epilepsy (Started Jun 01, 2012)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Apr 04, 2013 1500 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major MildMildMildMildMild AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
Purpose: Epilepsy (Started Dec 13, 2012)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Mar 25, 2013 1000 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate ModerateModerateModerateModerateModerate AlwaysAlwaysAlwaysAlwaysAlways A littleA littleA littleA littleA little
  • Icon_thumb_off 0 helpful marks
Purpose: Epilepsy (Started Feb 09, 2011)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Mar 14, 2013 1500 mg Daily Led_efficacy_1Led_defaultLed_defaultLed_defaultNone SevereSevereSevereSevereSevere AlwaysAlwaysAlwaysAlwaysAlways VeryVeryVeryVeryVery
  • Icon_thumb_off 0 helpful marks
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What is levetiracetam?

Levetiracetam is an anti-epileptic drug.

Levetiracetam is used to treat partial onset seizures in adults and children who are at least 4 years old.

Levetiracetam is also used to treat tonic-clonic seizures in adults and children who are at least 6 years old, and myoclonic seizures in adults and children who are at least 12 years old.

Levetiracetam may also be used for other purposes not listed in this medication guide.


Precautions

You should not use this medication if you are allergic to levetiracetam.

Before using this medication, tell your doctor if you are allergic to any drugs, or if you have kidney disease. You may need a dose adjustment or special tests during treatment.

You may have thoughts about suicide while taking this medication. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

FDA pregnancy category C. It is not known whether levetiracetam is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

Levetiracetam can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medication to a child without the advice of a doctor.

Avoid drinking alcohol. It can increase some of the side effects of levetiracetam and may also increase the risk of seizures.

Levetiracetam can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

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Instructions

Seek emergency medical treatment if you think you have used too much of this medicine.

Overdose symptoms may include drowsiness, agitation, aggression, shallow breathing, weakness, or fainting.

If you have missed your dose by only a few hours, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

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Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have any of these serious side effects:

  • hallucinations;
  • fever, chills, body aches, flu symptoms;
  • weakness, lack of coordination;
  • increasing or worsening seizures; or
  • nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • dizziness, spinning sensation;
  • drowsiness;
  • feeling irritable;
  • headache;
  • runny nose, sore throat; or
  • neck pain.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

There may be other drugs that can interact with levetiracetam. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Other Names

Keppra, levetiracetam, and Keppra XR

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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