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What is Milnacipran?

Milnacipran is a serotonin/norepinephrine reuptake inhibitor (SNRI) antidepressant. It is used in the treatment of depression and has demonstrated significant improvements in multiple aspects of fibromyalgia, including pain, patient global assessment and physical function.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Fibromyalgia 832 336 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Pain 99 39 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Depressed mood 58 21 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Joints ache (whole body) 24 8 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Fatigue 14 5 Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
ALL LISTED ABOVE 6 0

See all 859 patients currently taking Milnacipran

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Reported Side Effects

Side effects as an overall problem

Severe
 119
Moderate
 90
Mild
 94
None
 71

Commonly reported side effects, conditions, and hospitalizations associated with Milnacipran

Nausea 64
Hot flashes 31
Sweating excessive 30
Headaches 24
Constipation 24
Dizziness 19
See all 183 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Milnacipran. See all 31 dosages ►

  daily 2 mg daily 12.5 mg daily 25 mg daily 50 mg daily 75 mg daily 100 mg daily 150 mg daily 200 mg daily 300 mg daily
  71 Number of Patients: 71 5 Number of Patients: 5 51 Number of Patients: 51 83 Number of Patients: 83 142 Number of Patients: 142 10 Number of Patients: 10 435 Number of Patients: 435 37 Number of Patients: 37 127 Number of Patients: 127 4 Number of Patients: 4  

Reported Stop Reasons

Why Patients Stopped Taking Milnacipran (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 193   Side effects too severe: 61%
Did not seem to work 118   Did not seem to work: 37%
Doctor's advice 56   Doctor's advice: 18%
Expense 32   Expense: 10%
Other 21   Other: 7%
Personal research 9   Personal research: 3%
Change in health plan coverage 6   Change in health plan coverage: 2%
Course of treatment ended 5   Course of treatment ended: 2%
Not indicated 5   Not indicated: 2%

See all 307 patients who’ve stopped taking Milnacipran

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Milnacipran

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Milnacipran

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Milnacipran

Always
 327 87%
Usually
 31 8%
Sometimes
 5 1%
Never
 11 3%

Burden

Difficulty being on treatment

Burden of Milnacipran

Very
 31 8%
Somewhat
 36 10%
A little
 70 19%
Not at all
 237 63%

Cost

Paid out of pocket

Cost of Milnacipran

$200+
 4 2%
$100-199
 27 10%
$50-99
 57 22%
$25-49
 87 33%
< $25
 85 32%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 28, 2012.