What is pentosan polysulfate sodium?
Pentosan polysulfate sodium works like an anticoagulant (blood thinner) that prevents the formation of blood clots. However, it is used to treat bladder pain and discomfort caused by cystitis (bladder inflammation or irritation).
Pentosan polysulfate sodium may also be used for other purposes not listed in this medication guide.
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Precautions
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Instructions
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Side Effects
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Interactions
Precautions
You should not use this medication if you are allergic to pentosan polysulfate sodium.
Before taking pentosan polysulfate sodium, tell your doctor if you are allergic to any drugs, or if you have:
- a bleeding or blood clotting disorder;
- a history of aneurysm or stroke;
- a stomach ulcer, intestinal polyps or diverticulitis; or
- liver disease.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take pentosan polysulfate sodium.
FDA pregnancy category B. Pentosan polysulfate sodium is not expected to be harmful to an unborn baby. However, tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether pentosan polysulfate sodium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using pentosan polysulfate sodium.
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Instructions
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include easy bruising or unusual bleeding.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
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Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any easy bruising or unusual bleeding such as:
- nosebleed;
- blood in your urine or stools;
- rectal bleeding;
- coughing up blood;
- bleeding gums; or
- feeling like you might pass out.
Less serious side effects may include:
- hair loss;
- nausea, diarrhea, stomach pain;
- headache;
- mild dizziness;
- depressed mood; or
- mild itching or skin rash.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
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Interactions
Tell your doctor if you use any other medications that can increase your risk of bleeding, such as:
- heparin or warfarin (Coumadin);
- aspirin;
- alteplase (Activase);
- anistreplase (Eminase);
- clopidogrel (Plavix);
- dipyridamole (Persantine);
- streptokinase (Kabikinase, Streptase);
- ticlopidine (Ticlid);
- urokinase (Abbokinase); or
- an NSAID (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Cataflam, Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), or piroxicam (Feldene).
This list is not complete and there may be other drugs that can interact with pentosan polysulfate sodium. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Other Names
Elmiron and pentosan polysulfate sodium
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Disclaimer
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04
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