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Home > Community Treatment Reports > 4-Aminopyridine (4-AP) Treatment Report
What is 4-Aminopyridine (4-AP)?

4-Aminopyridine (4-AP) is a potassium channel blocker. It acts by blocking potassium channels in damaged nerve fibers enabling the axon to transmit nerve impulses again. It has been under study for spinal cord injuries and for Multiple Sclerosis.

Side Effects

Side effects as an overall problem

Severe
2 6%
Moderate
3 9%
Mild
5 14%
None
25 71%

Most commonly reported side effects

speedy feeling
3 9%
Anxiety
2 6%
tingling
2 6%
Dizziness/feeling like passing out
2 6%
chills
1 3%
Tingling in face
1 3%
  • Mild
  • Moderate
  • Severe

Dosages

Top 10 dosages based on patients currently taking 4-Aminopyridine (4-AP). See all 24 dosages ►

  1other as needed 20 mg as needed 5mg as needed daily 2 daily 2 other daily 3 mg daily 3.5 mg daily 5 mg daily 7.5 mg daily 10 g daily 10 mcg daily 10 mg daily 12 mg daily 12.5 mg daily 15 mg daily 20 mg daily 25 mg daily 30 mg daily 222 mg weekly 37.5 mg daily 40 mg daily 50 mg daily 60 mg daily
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 4 Number of Patients: 4 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 27 Number of Patients: 27 1 Number of Patients: 1 1 Number of Patients: 1 10 Number of Patients: 10 46 Number of Patients: 46 3 Number of Patients: 3 25 Number of Patients: 25 1 Number of Patients: 1 1 Number of Patients: 1 5 Number of Patients: 5 1 Number of Patients: 1 3 Number of Patients: 3  

Stop Reasons

Why Patients Stopped Taking 4-Aminopyridine (4-AP) (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work
11 35% Did not seem to work: 35%
Side effects too severe
7 23% Side effects too severe: 23%
Doctor's advice
6 19% Doctor's advice: 19%
Other
6 19% Other: 19%
Expense
4 13% Expense: 13%
Personal research
2 6% Personal research: 6%
Course of treatment ended
2 6% Course of treatment ended: 6%
Not indicated
1 3% Not indicated: 3%

See all 31 patients who’ve stopped taking 4-Aminopyridine (4-AP)

Duration See details about how long patients take this treatment ▼

Currently Taking 4-Aminopyridine (4-AP)

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
2
9
17
23
20
13

Stopped Taking 4-Aminopyridine (4-AP)

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
7
5
9
5
2
3

Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Always
27 77%
Usually
6 17%
Sometimes
1 3%
Never
1 3%

Burden

Difficulty being on treatment

Very
1 3%
Somewhat
2 6%
A little
5 14%
Not at all
27 77%

Cost

Paid out of pocket

$200+
0 0%
$100-199
3 9%
$50-99
14 40%
$25-49
7 20%
< $25
4 11%

Report created on November 22, 2009.