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Brand Names: Fampridine, Fampridine-SR
See also: Chlorella

What is 4-Aminopyridine (4-AP)? A drug currently in phase 2 clinical trials for MS, 4-Aminopyridine blocks potassium channels and prolongs action potentials thereby increasing transmitter release at the neuromuscular junction and elsewhere. Read more...Click to read more below


Reasons Taken

66 patients in the community are taking or have taken 4-Aminopyridine (4-AP).

Reason # Patients Percentage of patients
Other 22 37%
Fatigue 10 17%
Stiffness/spasticity 7 12%
Mobility 5 8%
Slow my MS progress 4 6%
disease-related symptoms 3 5%
Numbness in my hands, arms, legs, and waist 1 1%
Brain fog 1 1%
I walk slower tire more easily 1 1%
Neuropathy pain 1 1%
Sensation 1 1%
Weakness in legs 1 1%
Uhthoff's phenomenon 1 1%

Dosages

Based on the patients currently taking 4-Aminopyridine (4-AP).

Top 10 (Show all)

All (Show Top 10)

  0 mg day 0 day 0 mg none 2 day 5 mg day 7.5 mg day 10 mg day 15 mg day 20 mg day 30 mg day 35 mg day 37.5 mg day 40 mg day 40 tbs. day 50 mg day 60 mg day
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 3 Number of Patients: 3 1 Number of Patients: 1 6 Number of Patients: 6 4 Number of Patients: 4 16 Number of Patients: 16 11 Number of Patients: 11 1 Number of Patients: 1 1 Number of Patients: 1 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1  

Duration

How long current patients have been taking 4-Aminopyridine (4-AP) or how long patients were taking 4-Aminopyridine (4-AP) before stopping.

Currently taking 4-Aminopyridine (4-AP)

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
12
10
1
12
9
5

Stopped taking 4-Aminopyridine (4-AP)

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
1
1
1
1
0
1
Why Patients Stopped Taking 4-Aminopyridine (4-AP) (multiple reasons could be selected)
Reason # Patients Percentage of patients
Other 3 50% Other: 50%
Did not seem to work 2 33% Did not seem to work: 33%
Personal research 1 17% Personal research: 17%

Patient Reported Evaluations

Results from 6 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Major 50% 2
Moderate 50% 2

Other

Side-effects (as an overall problem)

Severe 0% 0
Moderate 17% 1
Mild 17% 1
None 67% 4

Top reported side-effects include: Anxiety, Nausea, Dizziness/feeling like passing out

Summary results are based on 6 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (2 of 6)

  • Lillian
    Sensation: none
    Overall: none
    Cognition: none
    Vision: none
    Speech: none
    Swallowing: none
    Upper limb: mild
    Walking: moderate
    See profile
  • Lillian
  • by Lillian
    Aug 20, 2006
  • EfficacyMajor
  • Side-effectsNone
  • Other
Advice/Tips
How much it will improve the quality of their life.

  • Flowers
    Flare-up: severe
    Sensation: moderate
    Overall: moderate
    Cognition: moderate
    Vision: moderate
    Speech: moderate
    Swallowing: moderate
    Upper limb: moderate
    Walking: moderate
    See profile
  • Flowers
  • by Flowers
    Aug 21, 2008
  • EfficacyMajor
  • Side-effectsModerate
  • Numbness in my hands, arms, legs, and waist
Advice/Tips
This drug has worked for me like a MIRACLE I was able to use it to recover from a major relapse instead of using IVSM

See all evaluation results for 4-Aminopyridine (4-AP)



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