What is Alpha Lipoic Acid?

An example of Alpha Lipoic Acid

Alpha Lipoic Acid, also known as Lipoic and Thioctic acid, is an antioxidant that has been used in the treatment of Vitamin C or E deficiency.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
89 17 Efficacy_slight Efficacy_none Efficacy_cant_tell
89 13 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
43 16 Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
15 4 Efficacy_cant_tell
14 3 Efficacy_none
12 2 Efficacy_moderate Efficacy_slight

See all 299 patients currently taking Alpha Lipoic Acid

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Reported Side Effects

Side effects as an overall problem

Severe
1
Moderate
3
Mild
6
None
69

Commonly reported side effects, conditions, and hospitalizations associated with Alpha Lipoic Acid

2
2
2
1
1
1
See all 8 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Alpha Lipoic Acid. See all 46 dosages

  daily 100 mg daily daily daily 200 mg daily daily 300 mg daily 400 mg daily daily 600 mg daily
  69 Number of Patients: 69 37 Number of Patients: 37 14 Number of Patients: 14 18 Number of Patients: 18 22 Number of Patients: 22 15 Number of Patients: 15 23 Number of Patients: 23 9 Number of Patients: 9 12 Number of Patients: 12 26 Number of Patients: 26  

Reported Stop Reasons

Why Patients Stopped Taking Alpha Lipoic Acid (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 53   Did not seem to work: 46%
Other 32   Other: 28%
Expense 17   Expense: 15%
Personal research 8   Personal research: 7%
Not indicated 5   Not indicated: 4%
Side effects too severe 4   Side effects too severe: 4%
Course of treatment ended 2   Course of treatment ended: 2%
Doctor's advice 2   Doctor's advice: 2%

See all 110 patients who’ve stopped taking Alpha Lipoic Acid

Currently Taking Alpha Lipoic Acid

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Alpha Lipoic Acid

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Alpha Lipoic Acid

Always
46 58%
Usually
19 24%
Sometimes
9 11%
Never
5 6%

Burden

Difficulty being on treatment

Burden of Alpha Lipoic Acid

Very
1 1%
Somewhat
6 8%
A little
22 28%
Not at all
50 63%

Cost

Paid out of pocket

Cost of Alpha Lipoic Acid

$200+
2 4%
$100-199
1 2%
$50-99
1 2%
$25-49
8 16%
< $25
37 76%

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17 patient evaluations for Alpha Lipoic Acid

  • satyr66
    Sex: M
    Data Quality: 2 stars
    MS: 19 yrs
    Type: Secondary Progressive
    Sensation: None
    Overall: Mild
    Cognition: moderate
    Vision: none
    Speech: none
    Swallowing: none
    Upper limb: moderate
    Walking: moderate
  • 24265-thumb
  • See satyr66's full Alpha Lipoic Acid history
Purposes: Vitamin E deficiency, Vitamin C deficiency, and vitamin E Deficiency (Started Feb 01, 2012)
Date Dosage Vitamin E deficiency Perceived effectiveness Vitamin C deficiency Perceived effectiveness vitamin E Deficiency Perceived effectiveness Side Effects Adherence Burden
Nov 24, 2012   Led_efficacy_1Led_defaultLed_defaultLed_default Led_efficacy_1Led_defaultLed_defaultLed_default MildMildMildMild AlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at all
Feb 20, 2012   ? ? NoneNoneNoneNone AlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at all
Feb 06, 2012 200 mg Daily ? ? NoneNoneNoneNone AlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
Purposes: MS (Multiple Sclerosis) and General health (Started Jan 01, 2012)
Date Dosage MS (Multiple Sclerosis) Perceived effectiveness General health Perceived effectiveness Side Effects Adherence Burden
Nov 04, 2012 300 mg Daily Led_efficacy_2Led_efficacy_2Led_defaultLed_defaultSlight Led_efficacy_2Led_efficacy_2Led_defaultLed_defaultSlight NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Jan 08, 2012 300 mg Daily ?Can't tell Led_efficacy_2Led_efficacy_2Led_defaultLed_defaultSlight NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Date
Nov 04, 2012
Advice & Tips
I take this mostly every day. It is difficult for me to say this drug does anything specific. I know it is an antioxidant that naturally occurs in the body and is used in respiration. I find that I am less tired when I take this drug. For more information visit this website for the exact form I take: http://www.lef.org/Vitamins-Supplements/Item01208/Super-R-Lipoic-Acid.html 16777216
Cost
< $25 monthly
Date
Jan 08, 2012
Advice & Tips
I am currently trying this naturally occurring, but synthetically produced drug. I haven't taken this long enough to see any definite positive effects toward MS symptoms. I don't have symptoms of MS often enough to make a definite correlation anyway. It seems to have made it more easy to stay up late, without feeling tired or becoming sluggish. This supplement (not a vitamin) is crucial to chemical respiration, recommended for MS by holistic doctors in MS society magazines, it has been shown to be at low levels in people suffering from conic illness. I don't believe it has any negative symptoms, but take at your own risk not evaluated by the FDA.
Cost
< $25 monthly
  • Icon_thumb_off 0 helpful marks
Purpose: Heavy Metal Toxicity (Started Sep 08, 2010)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Oct 13, 2012 100 mg Daily Led_efficacy_1Led_defaultLed_defaultLed_defaultNone NoneNoneNoneNoneNone UsuallyUsuallyUsuallyUsuallyUsually A littleA littleA littleA littleA little
  • Icon_thumb_off 0 helpful marks
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What is alpha-lipoic acid?

Alpha-lipoic acid is a naturally occurring fatty acid that can be found in many foods such as yeast, spinach, broccoli, potatoes, and organ meats such as liver or kidney.

Alpha-lipoic acid has been used as a nutritional supplement and antioxidant.

Not all uses for alpha-lipoic acid have been approved by the FDA. Alpha-lipoic acid should not be substituted for medications prescribed for you by your doctor.

Alpha-lipoic acid is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Alpha-lipoic acid may also be used for other purposes not listed in this product guide.


Precautions

Talk with a doctor, pharmacist, herbalist, or other healthcare provider before using alpha-lipoic acid if you have:

  • liver disease;
  • kidney disease;
  • diabetes;
  • low blood sugar (hypoglycemia); or
  • a thyroid disorder.

It is not known whether alpha-lipoic acid is harmful to an unborn baby. Do not use this product without talking to a healthcare provider if you are pregnant or plan to become pregnant during treatment.

Alpha-lipoic acid may pass into breast milk and may harm a nursing baby. Ask your healthcare provider before using alpha-lipoic acid if you are breast-feeding a baby.

Do not give any herbal/health supplement to a child without the advice of a doctor.

Follow your healthcare provider’s instructions about any restrictions on food, beverages, or activity while you are using alpha-lipoic acid.

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Instructions

Seek emergency medical attention if you think you have used too much of this product.

Consult your doctor, pharmacist, herbalist, or other healthcare provider for instructions if you miss a dose.

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Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your doctor, pharmacist, herbalist, or other healthcare provider if you have any of these signs of low blood sugar while taking alpha-lipoic acid:

  • hunger, weakness, nausea, irritability, tremors;
  • drowsiness, dizziness, headache, blurred vision;
  • confusion, trouble concentrating;
  • sweating, fast heart rate; or
  • feeling like you might pass out.

Less serious side effects may include:

  • upset stomach;
  • numbness or tingly feeling;
  • dizziness, tired feeling;
  • headache, muscle cramps; or
  • mild skin rash.

Tell your doctor, pharmacist, herbalist, or other healthcare provider about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

Do not take alpha-lipoic acid without the advice of a healthcare provider if you are using any of the following medications:

  • levothyroxine (Synthroid) and other thyroid medications; or
  • insulin or diabetes medications you take by mouth such as metformin (Glucophage), glyburide (DiaBeta, Glynase), and others.

This list is not complete and there may be other drugs that can interact with alpha-lipoic acid. Tell your healthcare provider about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your healthcare provider.

Other Names

Alpha-Lipoic Acid, alpha-lipoic acid, Alpha Lipoic, Alpha Lipoic Acid, Alpha-Lipoic-Acid-300, and thioctic acid

Available Strengths & Dosages


Route Form Strength
oral tablet 50 mg
oral tablet 100 mg

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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