What is pancrelipase?
Pancrelipase is a combination of three enzymes (proteins): lipase, protease, and amylase. These enzymes are normally produced by the pancreas and are important in the digestion of fats, proteins, and sugars.
Pancrelipase is used to replace these enzymes when the body does not have enough of its own. Certain medical conditions can cause this lack of enzymes, including cystic fibrosis, chronic inflammation of the pancreas, or blockage of the pancreatic ducts.
Pancrelipase may also be used following surgical removal of the pancreas.
Pancrelipase may also be used for purposes other than those listed in this medication guide.
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Precautions
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Instructions
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Side Effects
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Interactions
Precautions
You should not take pancrelipase if you are allergic to pork proteins.
Before taking pancrelipase, tell your doctor if you are allergic to any drugs, or if you have:
- a sudden onset of pancreatitis; or
- worsening of chronic pancreatic disease.
If you have any of these conditions, you may need a dose adjustment or special tests to safely use this medication.
This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether pancrelipase passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using pancrelipase.
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Instructions
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include diarrhea or stomach upset.
Skip the missed dose and wait until your next scheduled dose to take the medicine. Do not take extra medicine to make up the missed dose.
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Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
- nausea or vomiting;
- stomach pain or upset;
- diarrhea or constipation;
- greasy stools;
- rectal irritation; or
- bloating or gas.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
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Interactions
This list is not complete and there may be other drugs that can interact with pancrelipase. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Other Names
Arco-Lase, Cotazym, Cotazym-S, Creon 10, Creon 20, Creon 5, Dygase, Encron-10, Ilozyme, Ku-Zyme, Ku-Zyme HP, Kutrase, Lapase, Lipram-CR, Lipram-CR5, Lipram-UL 12, Lipram-UL 18, Palcaps 10, Panase, Pancrease MT 10, Pancrease MT 16, Pancrease MT 20, Pancrease MT 4, Pancrecarb MS-16, Pancrecarb MS-4, Pancrecarb MS-8, Pancron D/R, Panocaps, Panocaps MT 16, Protilase, Protilase MT-16, Ultrase, Ultrase MT 12, Ultrase MT 18, Ultrase MT 20, Vio-Moore, Viokase, Viokase 16, Viokase 8, Zymase, pancrelipase, Lipram, Lipram-CR10, Lipram-CR20, Lipram-PN10, Lipram-PN16, Lipram-PN20, Lipram-UL 20, Pancrease, Pancreatil-UL 12, Pangestyme CN 10, Pangestyme CN 20, Pangestyme EC, Pangestyme MT 16, Pangestyme UL 18, Pangestyme UL 20, Panokase, Panokase 16, and Plaretase
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Disclaimer
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04
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