What is ALS?

ALS (amyotrophic lateral sclerosis) is a degenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and spinal cord. Symptoms include progressive weakness, atrophy, fasciculation, dysphagia, and eventual paralysis of respiratory function.

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What is it like to have ALS?

Common Symptoms Patients' Latest Severity My Current Severity  
Severity
Severe
Moderate
Mild
None
Constipation None Mild Moderate Severe
Emotional lability None Mild Moderate Severe
Excess saliva None Mild Moderate Severe
Excessive yawning None Mild Moderate Severe
Fasciculations None Mild Moderate Severe
Stiffness/Spasticity None Mild Moderate Severe

What do patients take to treat ALS and its symptoms?

Commonly prescribed and frequently used treatments

  Efficacy Overall rating of side effects # of Evaluations
Riluzole
(Rilutek)
256
Lithium Carbonate
(Teralithe, Maniprex, Lithionate, Eskalith CR)
87
CoQ10 (CoEnzyme Q10)
(Nutri-Dyn CoQ10, Whole Foods CoQ10 Chewable Tablets, Pure encapsulations CoQ10, Q Avail Nano powder)
49
Vitamin E
(Gamma E, Vitamin E topical, E 400iu Natural Source, Vitalady Tender Dry E)
32
27
22
22
Baclofen
(Kemstro, DOM-Baclofen, Gabalon, Spinax)
20
Non-invasive Ventilator
(Elisee 150, SmartAir Plus, BiPAP w/humidifier, Trilogy 100)
17
Vitamin C (ascorbic acid)
(Usana PolyC-6, Esther-C, Kirkland Vitamin C, Natural Factors Vitamin C)
17
Creatine Monohydrate
(Jarrows Formulas Creatine Monohydrate, Pure Creatine)
16
Naltrexone
(ReVia, Low Dose Naltrexone (LDN))
15
Acupuncture
(Forever Needle implants, East Asian therapy, 4 needle technique, Acupuncture low-concentration alkali injection therapy)
15
Alpha Lipoic Acid
(Ciagen, Solgar Alpha Lipoic Acid, Planetary Herbals Alpha Lipooic Acid, Tiobec)
14
8

These charts show data from ALS patients' latest treatment evaluations

Who has ALS at PatientsLikeMe?

<20 20-29 30-39 40-49 50-59 60-69 70+
Current Age
Distribution of females vs. males
Gender
42% Females
58% Males
Age at first symptom
Age at first symptom # of patients Proportion
0-19 yrs 26
20-29 yrs 158
30-39 yrs 488
40-49 yrs 872
50-59 yrs 986
60-69 yrs 594
70+ yrs 129
Diagnosis status
Diagnosis status # of patients Proportion
Diagnosed 3453
Not Officially Diagnosed 135

These charts show data from ALS patients who have completed their condition history