What is hereditary spastic paraplegia?

Hereditary Spastic Paraplegia is not a single disease but a group of genetic disorders in which the main feature is progressive spasticity in the lower limbs due to pyramidal tract dysfunction. Onset can be at any age, from the first year of life to old age, depending on the specific genetic form.

How do members experience hereditary spastic paraplegia?

Top 5 symptoms reported by people with hereditary spastic paraplegia*

*Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.

Top treatments taken by people for hereditary spastic paraplegia*

*Data from patients with hereditary spastic paraplegia, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.

Compare treatments taken by people with hereditary spastic paraplegia*

Treatment
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment

(Mylan-Baclofen)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
hereditary spastic paraplegia (2)
Treatment

(Zanaflex)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
hereditary spastic paraplegia (1)

*Data from patients with hereditary spastic paraplegia, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.

Who has hereditary spastic paraplegia on PatientsLikeMe?

Age

Age Proportion # of patients
<20 3
20s 12
30s 32
40s 45
50s 56
60s 72
70+ 40

Distribution of sex

Sex

Sex Proportion # of patients
Male 105
Female 159