Major Depressive Disorder

We’re all in this for good.

By sharing your stories and data, you will:
  • help each other live better and uncover the best ways to manage your health today
  • help researchers shorten the path to new treatments tomorrow

How much good can your data do? A whole lot, as co-founder Jamie Heywood explains in this video.

What is Major Depressive Disorder?

Major depressive disorder, also known as clinical depression, is marked by depressed mood, inactivity, lack of interest, insomnia, feelings of worthlessness, diminished ability to think, and may include thoughts of suicide.

What is it like to have Major Depressive Disorder?

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, insomnia, fatigue, and pain) regardless of condition.
Last updated:

What do patients take to treat Major Depressive Disorder and its symptoms?

You’ve tried
Treatment name(s)
Type
How many have tried
How many evaluations
Treatment name(s)

(Cymbalta, Cymgen, Yelate) 1 more
Type
Prescription Drug
How many have tried
565
How many evaluations
309
Treatment name(s)

(Aplenzin, Budeprion SR, Budeprion XL) 12 more
Type
Prescription Drug
How many have tried
534
How many evaluations
286
Treatment name(s)
Type
Psychotherapy
How many have tried
473
How many evaluations
133
Treatment name(s)

(Altruline, Apo-Sertraline, Daxid) 11 more
Type
Prescription Drug
How many have tried
441
How many evaluations
218
Treatment name(s)

(APO-Citalopram, Alcytan, Celexa) 15 more
Type
Prescription Drug
How many have tried
430
How many evaluations
237
Treatment name(s)

(Actan, Flunil, Fluxene) 15 more
Type
Prescription Drug
How many have tried
402
How many evaluations
214
Treatment name(s)

(Effexor, Effexor XR, Novo-Venlafaxine XR) 9 more
Type
Prescription Drug
How many have tried
402
How many evaluations
191
Treatment name(s)

(Cipralex, Es Pramcit, Esipram) 6 more
Type
Prescription Drug
How many have tried
285
How many evaluations
159
Treatment name(s)

(APO Clonazepam, Clonex, Clonotril) 7 more
Type
Prescription Drug
How many have tried
245
How many evaluations
134
Treatment name(s)

(Cobalt-Quetiapine, Dopaquel, Ketipinor) 4 more
Type
Prescription Drug
How many have tried
167
How many evaluations
90
See all 760 treatments
Data from patients with Major Depressive Disorder, who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

Compare treatments for Major Depressive Disorder

You’ve tried
Treatment name(s)
How many have tried
Perceived effectiveness
Side effects
How many evaluations
Treatment name(s)

(Cymbalta, Cymgen, Yelate) 1 more
How many have tried
565
Perceived effectiveness
Side effects
Nausea Weight gain 134 more
How many evaluations
309
Treatment name(s)

(Aplenzin, Budeprion SR, Budeprion XL) 12 more
How many have tried
534
Perceived effectiveness
Side effects
Nausea Anxious mood 113 more
How many evaluations
286
Treatment name(s)
How many have tried
473
Perceived effectiveness
Side effects
Anxious mood Anger 17 more
How many evaluations
133
Treatment name(s)

(Altruline, Apo-Sertraline, Daxid) 11 more
How many have tried
441
Perceived effectiveness
Side effects
Weight gain Fatigue 117 more
How many evaluations
218
Treatment name(s)

(APO-Citalopram, Alcytan, Celexa) 15 more
How many have tried
430
Perceived effectiveness
Side effects
Sex drive (libido) decreased Difficulty with orgasm 89 more
How many evaluations
237
Treatment name(s)

(Actan, Flunil, Fluxene) 15 more
How many have tried
402
Perceived effectiveness
Side effects
Nausea Vivid dreams 100 more
How many evaluations
214
Treatment name(s)

(Effexor, Effexor XR, Novo-Venlafaxine XR) 9 more
How many have tried
402
Perceived effectiveness
Side effects
Dry mouth Weight gain 111 more
How many evaluations
191
Treatment name(s)

(Cipralex, Es Pramcit, Esipram) 6 more
How many have tried
285
Perceived effectiveness
Side effects
Weight gain Sex drive (libido) decreased 75 more
How many evaluations
159
Treatment name(s)

(APO Clonazepam, Clonex, Clonotril) 7 more
How many have tried
245
Perceived effectiveness
Side effects
Drowsiness Sleepiness 40 more
How many evaluations
134
Treatment name(s)

(Cobalt-Quetiapine, Dopaquel, Ketipinor) 4 more
How many have tried
167
Perceived effectiveness
Side effects
Weight gain Excessive daytime sleepiness (somnolence) 49 more
How many evaluations
90
See all 760 treatments
Data from patients with Major Depressive Disorder, who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Who has Major Depressive Disorder on PatientsLikeMe?


Age
Age Proportion # of patients
<20 233
20s 2,392
30s 3,428
40s 3,914
50s 3,253
60s 1,242
70+ 175

Gender

Distribution of females vs. males

78% Females
22% Males
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 3,852
20-29 years 1,527
30-39 years 1,026
40-49 years 555
50-59 years 186
60-69 years 18
70+ years 2

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 11,027
Not Diagnosed 1,957

These charts show data from Major Depressive Disorder patients who have completed their condition history
Last updated: