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Home > Community Treatment Reports > Dalfampridine Treatment Report
What is Dalfampridine?

Dalfampridine is a potassium channel blocker that acts by blocking potassium channels in damaged nerve fibers enabling the axon to transmit nerve impulses again. It is indicated as a treatment to improve walking in patients with multiple sclerosis (MS).

Reasons taken & Efficacy

Reasons and Efficacy
Reasons taken
# of patients Efficacy
Major
Moderate
Slight
None
Can’t tell 		# of patients evaluated by
Mobility 146 66
Walking problems 77 33
Multiple Sclerosis MS 67 23
helps nerve signal conduction 38 25
Fatigue 32 9
helps leg strength 24 6

See all 433 patients currently taking Dalfampridine

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Side Effects

Side effects as an overall problem

Severe
9
Moderate
24
Mild
39
None
79

Most commonly reported side effects

Insomnia
10
Dizziness
6
Headaches
5
Constipation
5
Dizziness/feeling like passing out
5
Nausea
4
  • Mild
  • Moderate
  • Severe

Dosages

Top 10 dosages based on patients currently taking Dalfampridine. See all 32 dosages ►

  10mg as needed 1other as needed 20 mg as needed 5mg as needed 60mg as needed daily 10 mg monthly 10 mg 1 mg daily 1 other daily 2 mcg daily 2 mg daily 2 other daily 3 mg daily 3.5 mg daily 5 mg daily 10 g daily 10 mg daily 12 mg daily 12.5 mg daily 15 mg daily 20 mcg daily 20 mg daily 25 mg daily 30 mg daily 222 mg weekly 37.5 mg daily 40 mg daily 60 mg daily 100 mg daily 200 mg daily 250 mg daily
  2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 6 Number of Patients: 6 2 Number of Patients: 2 1 Number of Patients: 1 9 Number of Patients: 9 5 Number of Patients: 5 1 Number of Patients: 1 1 Number of Patients: 1 8 Number of Patients: 8 1 Number of Patients: 1 95 Number of Patients: 95 1 Number of Patients: 1 1 Number of Patients: 1 11 Number of Patients: 11 1 Number of Patients: 1 243 Number of Patients: 243 3 Number of Patients: 3 24 Number of Patients: 24 1 Number of Patients: 1 1 Number of Patients: 1 10 Number of Patients: 10 4 Number of Patients: 4 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1  

Stop Reasons

Why Patients Stopped Taking Dalfampridine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work
35   Did not seem to work: 43%
Side effects too severe
22   Side effects too severe: 27%
Other
21   Other: 26%
Doctor's advice
13   Doctor's advice: 16%
Expense
9   Expense: 11%
Not indicated
5   Not indicated: 6%
Personal research
3   Personal research: 4%
Course of treatment ended
2   Course of treatment ended: 2%

See all 80 patients who’ve stopped taking Dalfampridine

Duration See details about how long patients take this treatment ▼

Currently Taking Dalfampridine

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Dalfampridine

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Always
124 82%
Usually
19 13%
Sometimes
3 2%
Never
5 3%

Burden

Difficulty being on treatment

Very
3 2%
Somewhat
10 7%
A little
22 15%
Not at all
116 77%

Cost

Paid out of pocket

$200+
3 2%
$100-199
10 7%
$50-99
36 24%
$25-49
58 38%
< $25
22 15%

Report created on September 09, 2010.