Most Popular Brands: Fampridine
4-Aminopyridine (4-AP) is a potassium channel blocker. It acts by blocking potassium channels in damaged nerve fibers enabling the axon to transmit nerve impulses again. It has been under study for spinal cord injuries and for Multiple Sclerosis.
| Reasons taken |
# of patients
Efficacy
|
Major | Moderate | Slight | None | Can’t tell | # of patients evaluated by |
|---|---|---|---|---|---|---|---|
| Mobility | 63 |
|
|
|
|
|
25 |
| Fatigue | 30 |
|
|
|
|
9 | |
| Other | 23 |
|
|
|
11 | ||
| Stiffness/Spasticity | 13 |
|
|
2 | |||
| MS Multiple Sclerosis | 7 | 0 | |||||
| Sensation | 6 |
|
1 |
See all 153 patients currently taking 4-Aminopyridine (4-AP)
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Top 10 dosages based on patients currently taking 4-Aminopyridine (4-AP). See all 25 dosages ►
| 1other as needed | 20 mg as needed | 5mg as needed | daily | 1 mg daily | 2 daily | 2 other daily | 3 mg daily | 3.5 mg daily | 5 mg daily | 7.5 mg daily | 10 g daily | 10 mcg daily | 10 mg daily | 12 mg daily | 12.5 mg daily | 15 mg daily | 20 mg daily | 25 mg daily | 30 mg daily | 222 mg weekly | 37.5 mg daily | 40 mg daily | 60 mg daily | 100 mg daily | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
1
|
1
|
1
|
2
|
1
|
1
|
1
|
1
|
1
|
5
|
2
|
1
|
1
|
35
|
1
|
1
|
11
|
46
|
4
|
27
|
1
|
1
|
6
|
3
|
1
|
||
| Reason | # Patients | Percentage of patients | |
|---|---|---|---|
|
Did not seem to work
|
15 | 39% |
|
|
Side effects too severe
|
8 | 21% |
|
|
Other
|
8 | 21% |
|
|
Doctor's advice
|
7 | 18% |
|
|
Expense
|
6 | 16% |
|
|
Course of treatment ended
|
2 | 5% |
|
|
Personal research
|
2 | 5% |
|
|
Not indicated
|
1 | 3% |
|
See all 38 patients who’ve stopped taking 4-Aminopyridine (4-AP)
Report created on February 09, 2010.