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Home > Community Treatment Reports > 4-Aminopyridine (4-AP) Treatment Report
What is 4-Aminopyridine (4-AP)?

4-Aminopyridine (4-AP) is a potassium channel blocker. It acts by blocking potassium channels in damaged nerve fibers enabling the axon to transmit nerve impulses again. It has been under study for spinal cord injuries and for Multiple Sclerosis.

Side Effects

Side effects as an overall problem

Severe
2 4%
Moderate
4 8%
Mild
8 17%
None
34 71%

Most commonly reported side effects

Dizziness/feeling like passing out
4 27%
speedy feeling
4 27%
Tingling
3 20%
Insomnia
2 13%
Nausea
2 13%
Anxiety
2 13%
  • Mild
  • Moderate
  • Severe

Dosages

Top 10 dosages based on patients currently taking 4-Aminopyridine (4-AP). See all 25 dosages ►

  1other as needed 20 mg as needed 5mg as needed daily 1 mg daily 2 daily 2 other daily 3 mg daily 3.5 mg daily 5 mg daily 7.5 mg daily 10 g daily 10 mcg daily 10 mg daily 12 mg daily 12.5 mg daily 15 mg daily 20 mg daily 25 mg daily 30 mg daily 222 mg weekly 37.5 mg daily 40 mg daily 60 mg daily 100 mg daily
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 5 Number of Patients: 5 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 35 Number of Patients: 35 1 Number of Patients: 1 1 Number of Patients: 1 11 Number of Patients: 11 46 Number of Patients: 46 4 Number of Patients: 4 27 Number of Patients: 27 1 Number of Patients: 1 1 Number of Patients: 1 6 Number of Patients: 6 3 Number of Patients: 3 1 Number of Patients: 1  

Stop Reasons

Why Patients Stopped Taking 4-Aminopyridine (4-AP) (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work
15 39% Did not seem to work: 39%
Side effects too severe
8 21% Side effects too severe: 21%
Other
8 21% Other: 21%
Doctor's advice
7 18% Doctor's advice: 18%
Expense
6 16% Expense: 16%
Course of treatment ended
2 5% Course of treatment ended: 5%
Personal research
2 5% Personal research: 5%
Not indicated
1 3% Not indicated: 3%

See all 38 patients who’ve stopped taking 4-Aminopyridine (4-AP)

Duration See details about how long patients take this treatment ▼

Currently Taking 4-Aminopyridine (4-AP)

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking 4-Aminopyridine (4-AP)

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Always
38 79%
Usually
7 15%
Sometimes
1 2%
Never
2 4%

Burden

Difficulty being on treatment

Very
1 2%
Somewhat
2 4%
A little
5 10%
Not at all
40 83%

Cost

Paid out of pocket

$200+
0 0%
$100-199
3 6%
$50-99
19 40%
$25-49
12 25%
< $25
6 13%

Report created on February 09, 2010.