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Home > Community Treatment Reports > Amitriptyline Treatment Report
What is Amitriptyline?

Amitriptyline is a tricyclic antidepressant approved for the treatment of depression. Off label amitripyline is used for certain chronic and neuropathic (nerve) pain and for prevention of migraine headaches.

Reasons taken & Efficacy

Reasons and Efficacy
Reasons taken # of patients Major Moderate Slight None Can’t tell # of patients evaluated by
Pain 132 35
Insomnia 118 29
Other 104 26
Excess saliva 74 9
Depression 67 21
Fibromyalgia 49 15

See all 679 patients currently taking Amitriptyline


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Side Effects

Side effects as an overall problem

Severe
24 15%
Moderate
36 22%
Mild
48 30%
None
53 33%

Most commonly reported side effects

dry mouth
50 31%
Weight gain
34 21%
Makes me groggy during the day
33 20%
Hangover effect, next day
26 16%
Excessive daytime sleepiness (somnolence)
24 15%
quick changes of mood
13 8%
  • Mild
  • Moderate
  • Severe

Dosages

Top 10 dosages based on patients currently taking Amitriptyline. See all 41 dosages

  100 mg all the time (24/7) 100mg as needed 10mg as needed 10mg/mL as needed 25 mg as needed 25mg as needed 50mg as needed 5 mg as needed daily 0.5 mg daily 1 tbs. daily 2 mg daily 3 mg daily 5 mg daily 8 mg daily 10 mg daily 10 other daily 15 mg daily 20 mg daily 24 mg daily 25 mg daily 30 mg daily 35 mg daily 37 mg daily 37.5 mg daily 40 mg daily 50 mcg daily 50 mg daily 70 mg daily 75 mg daily 75 mg one time 80 mg daily 100 mg daily 150 mg daily 200 mg daily 225 mg daily 300 mg daily 400 mg daily 500 mg daily 600 mg daily 750 mg daily
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 6 Number of Patients: 6 2 Number of Patients: 2 1 Number of Patients: 1 8 Number of Patients: 8 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 4 Number of Patients: 4 1 Number of Patients: 1 114 Number of Patients: 114 1 Number of Patients: 1 2 Number of Patients: 2 42 Number of Patients: 42 1 Number of Patients: 1 136 Number of Patients: 136 25 Number of Patients: 25 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1 10 Number of Patients: 10 1 Number of Patients: 1 150 Number of Patients: 150 3 Number of Patients: 3 45 Number of Patients: 45 1 Number of Patients: 1 1 Number of Patients: 1 77 Number of Patients: 77 11 Number of Patients: 11 8 Number of Patients: 8 1 Number of Patients: 1 2 Number of Patients: 2 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1  

Stop Reasons

Why Patients Stopped Taking Amitriptyline (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe
78 35% Side effects too severe: 35%
Did not seem to work
74 33% Did not seem to work: 33%
Doctor's advice
50 23% Doctor's advice: 23%
Other
41 18% Other: 18%
Course of treatment ended
14 6% Course of treatment ended: 6%
Personal research
7 3% Personal research: 3%
Not indicated
6 3% Not indicated: 3%
Expense
2 1% Expense: 1%

See all 212 patients who’ve stopped taking Amitriptyline

Currently Taking Amitriptyline

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
11
26
45
88
72
151

Stopped Taking Amitriptyline

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
35
39
37
32
23
47

Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Always
130 81%
Usually
22 14%
Sometimes
6 4%
Never
3 2%

Burden

Difficulty being on treatment

Very
19 12%
Somewhat
13 8%
A little
19 12%
Not at all
110 68%

Cost

Paid out of pocket

$200+
0 0%
$100-199
2 1%
$50-99
2 1%
$25-49
1 1%
< $25
101 63%

See more information, including instructions, precautions, side effects, and interactions.

Report created on November 20, 2009.