What is Levodopa-Benserazide?

Category: Prescription Drugs

Most popular types: Madopar Madopar dispersible Prolopa Show all

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Levodopa is the precursor molecule to dopamine, an important neurotransmitter implicated in the underlying cause of Parkinson's disease. Benserazide is an additive which allows the levodopa to continue circulating in the body for longer.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 92 107
Stiffness/spasticity 12 8
Multiple system atrophy 4 10
Tremor in hands 3 3
Improve mobility 2 0
Slow movement (bradykinesia) 2 1

Show all 16 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
8
Moderate
30
Mild
25
None
57

Commonly reported side effects and conditions associated with Levodopa-Benserazide

Side effect Patients
Constipation 4
Jerky movements (dyskinesia) 4
Nausea 4
Tiredness 4
Depressed mood 2
Dizziness 2

Show all 36 reported side effects

Dosages

Based on patients currently taking Levodopa-Benserazide

Dosage Patients
12.5-50 mg three times daily 2
100 mg daily 2
125 mg daily 2
100 mg three times daily 2
1 mg twice daily 1
1 capsule(s) three times daily 1
3 mg daily 1
1 mg four times daily 1
4 cap(s) daily 1
4 capsule(s) daily 1

See all 30 dosages

Why patients stopped taking Levodopa-Benserazide

Multiple reasons could be selected

Reason Patients
Doctor's advice 8
Other 8
Did not seem to work 4
Personal research 2
Side effects too severe 2
Change in health plan coverage 1
See all 21 patients who've stopped taking Levodopa-Benserazide

Duration

Currently taking Levodopa-Benserazide

Duration Patients
1 - 6 months 2
6 months - 1 year 1
1 - 2 years 4
2 - 5 years 8
5 - 10 years 12
10 years or more 4

Stopped taking Levodopa-Benserazide

Duration Patients
1 - 6 months 3
6 months - 1 year 5
1 - 2 years 7
2 - 5 years 6
5 - 10 years 2
Adherence
Adherence Evaluations
Always 99
Usually 18
Sometimes 1
Never taken as prescribed 2
Burden
Burden Evaluations
Very hard to take 1
Somewhat hard to take 16
A little hard to take 27
Not at all hard to take 76
Cost per month
Cost per month Evaluations
$200+ 4
$100-199 4
$50-99 4
$25-49 8
< $25 40
Not specified 60

What people switch to and from

Patients started taking Levodopa-Benserazide after stopping:

Treatment Patients
Levodopa-Benserazide (Madopar) 2
Carbidopa-Levodopa (Sinemet) 1
Carbidopa-Levodopa CR (Sinemet CR) 1
Ropinirole (Requip) 1
Rotigotine (Neupro Patch) 1

Patients stopped taking Levodopa-Benserazide and switched to:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 3
Levodopa-Benserazide (Madopar) 2
Amantadine (Symmetrel) 1
Last updated:

6 patient evaluations for Levodopa-Benserazide

Apr 15, 2015 (Started Apr 01, 2008)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 800 mg Daily
Advice & Tips: I had DBS surgery in February 2014. Professor David Williams effectively programmed my Neural Stimulator in April 2015. I now take 350 mg of Carbidopa/Levadopa per day.
Cost: < $25 monthly

  • 0 helpful marks

Jul 26, 2012 (Started Jan 25, 2005)

  • Effectiveness
    Moderate (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 375 mg Daily
Advice & Tips: Need to know risks on levodopa long term use.
Cost: < $25 monthly

Aug 25, 2011 (Started Jan 25, 2005)

  • Effectiveness
    Moderate (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: PD is a progressive illness. Really it is.
Cost: $25-49 monthly

  • 0 helpful marks

Jun 6, 2010 (Started Sep 27, 2006)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Cost: $25-49 monthly

Nov 9, 2009 (Started Sep 27, 2006)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 625 mg Daily
Cost: < $25 monthly

Sep 14, 2008 (Started Sep 27, 2006)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: results have varied a lot; the dose has been upped several times over 3 years
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 6 patient evaluations for Levodopa-Benserazide