What is Milnacipran?

Category: Prescription Drugs

Most popular types: Savella Ixel

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Milnacipran is a serotonin/norepinephrine reuptake inhibitor (SNRI) antidepressant. It is used in the treatment of depression and has demonstrated significant improvements in multiple aspects of fibromyalgia, including pain, patient global assessment and physical function.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 1,127 636
Pain 174 99
Depressed mood 97 54
Whole body joint ache 23 10
Fatigue 14 7

Show all 56 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 198
Moderate 161
Mild 166
None 163

Commonly reported side effects and conditions associated with Milnacipran

Side effect Patients
Nausea 91
Excessive sweating 36
Headaches 29
Hot flashes 29
Constipation 26
Dizziness 19

Show all 184 reported side effects

Dosages

Based on patients currently taking Milnacipran

Dosage Patients
100 mg daily 18
50 mg twice daily 13
100 mg twice daily 11
200 mg daily 8
12.5 mg daily 2
25 mg daily 2
25 mg twice daily 2
50 mg daily 2
150 mg daily 2
75 mg daily 1

Why patients stopped taking Milnacipran

Multiple reasons could be selected

Reason Patients
Side effects too severe 268
Did not seem to work 181
Doctor's advice 77
Expense 51
Other 35
Change in health plan coverage 18
Personal research 14
Course of treatment ended 6
See all 456 patients who've stopped taking Milnacipran

Duration

Currently taking Milnacipran

Duration Patients
1 - 6 months 2
6 months - 1 year 2
1 - 2 years 4
2 - 5 years 12
5 - 10 years 41

Stopped taking Milnacipran

Duration Patients
Less than 1 month 124
1 - 6 months 182
6 months - 1 year 53
1 - 2 years 46
2 - 5 years 39
5 - 10 years 10
10 years or more 2
Adherence
Adherence Evaluations
Always 592
Usually 59
Sometimes 10
Never taken as prescribed 27
Burden
Burden Evaluations
Very hard to take 53
Somewhat hard to take 58
A little hard to take 110
Not at all hard to take 467
Cost per month
Cost per month Evaluations
$200+ 16
$100-199 43
$50-99 85
$25-49 158
< $25 165
Not specified 221

What people switch to and from

Patients started taking Milnacipran after stopping:

Treatment Patients
Duloxetine (Cymbalta) 27
Pregabalin (Lyrica) 19
Gabapentin (Neurontin) 6
Nortriptyline (Pamelor) 2
Citalopram (Celexa) 1

Show all 12 treatments patients report switching from

Patients stopped taking Milnacipran and switched to:

Treatment Patients
Duloxetine (Cymbalta) 11
Pregabalin (Lyrica) 5
Gabapentin (Neurontin) 3
Naltrexone (Low Dose Naltrexone (LDN)) 2
Topiramate (Topamax) 2

Show all 15 treatments patients report switching to

Last updated:

74 patient evaluations for Milnacipran

Dec 12, 2012 (Started Aug 10, 2011)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    Mild (tiredness, Makes a little tired)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: It helps me with the pain and im able to do more than with out it.

  • 0 helpful marks

Oct 6, 2012 (Started Jun 15, 2012)

  • Effectiveness
    None (for fibromyalgia)
  • Effectiveness
    None (for pain)
  • Side effects
    Severe (serotonin syndrome)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: The reaction between this medication and another medication along with something I ate caused Serotonin Toxicity Syndrome putting me in the hospital for 3 days.
Cost: $25-49 monthly

  • 0 helpful marks

Aug 22, 2012 (Started Jun 14, 2012)

  • Effectiveness
    Can't tell (for major depressive disorder)
  • Effectiveness
    Can't tell (for depressed mood)
  • Effectiveness
    Slight (for fibromyalgia)
  • Side effects
    Moderate (nausea, MS hug (tight chest or torso), back pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: savella and plaqunil made me puke. taking savella at different time then plaqunil has helped 70% of the time.
Cost: $50-99 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 74 patient evaluations for Milnacipran