What is Modafinil?

Category: Prescription Drugs

Most popular types: Provigil Alertec Modiodal Show all

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Modafinil is stimulant used to improve wakefulness in patients narcolepsy and shift work sleep disorder or as an adjunctive therapy for obstructive sleep apnea. It may also be used for attention-deficit/hyperactivity disorder and to treat fatigue in MS and other disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fatigue 1,514 689
Multiple sclerosis 919 427
Excessive daytime sleepiness (somnolence) 499 341
Narcolepsy 100 54
Brain fog 80 49

Show all 92 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
72
Moderate
155
Mild
254
None
612

Commonly reported side effects and conditions associated with Modafinil

Side effect Patients
Jittery feeling 58
Headaches 56
Dry mouth 51
Anxious mood 36
Sleep problems 29
Heart rate increased 26

Show all 178 reported side effects

Dosages

Based on patients currently taking Modafinil

Dosage Patients
200 mg daily 93
100 mg daily 53
400 mg daily 30
200 mg twice daily 20
200mg as needed 13
100mg as needed 10
100 mg twice daily 5
400 mg twice daily 4
150 mg daily 3
50 mg daily 2

See all 28 dosages

Why patients stopped taking Modafinil

Multiple reasons could be selected

Reason Patients
Did not seem to work 280
Other 204
Side effects too severe 197
Expense 182
Doctor's advice 119
Change in health plan coverage 89
Personal research 35
Course of treatment ended 19
See all 870 patients who've stopped taking Modafinil

Duration

Currently taking Modafinil

Duration Patients
1 - 6 months 13
6 months - 1 year 11
1 - 2 years 23
2 - 5 years 40
5 - 10 years 102
10 years or more 66

Stopped taking Modafinil

Duration Patients
Less than 1 month 120
1 - 6 months 185
6 months - 1 year 128
1 - 2 years 145
2 - 5 years 193
5 - 10 years 76
10 years or more 26
Adherence
Adherence Evaluations
Always 742
Usually 219
Sometimes 96
Never taken as prescribed 36
Burden
Burden Evaluations
Very hard to take 36
Somewhat hard to take 64
A little hard to take 138
Not at all hard to take 855
Cost per month
Cost per month Evaluations
$200+ 88
$100-199 51
$50-99 135
$25-49 159
< $25 322
Not specified 338

What people switch to and from

Patients started taking Modafinil after stopping:

Treatment Patients
Methylphenidate (Ritalin) 25
Amphetamine-Dextroamphetamine (Adderall) 16
Armodafinil (Nuvigil) 14
Amantadine (Symmetrel) 9
Bupropion (Wellbutrin XL) 2

Show all 18 treatments patients report switching from

Patients stopped taking Modafinil and switched to:

Treatment Patients
Armodafinil (Nuvigil) 27
Amphetamine-Dextroamphetamine (Adderall) 25
Methylphenidate (Ritalin) 10
Dextroamphetamine (Dexedrine) 4
Amantadine (Symmetrel) 2

Show all 7 treatments patients report switching to

Last updated:

131 patient evaluations for Modafinil

Jan 26, 2016 (Started Oct 14, 2005)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Effectiveness
    Major (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Provigil remains my fantastic life changer, since it keeps me awake all day.
Cost: < $25 monthly

Apr 28, 2015 (Started Oct 14, 2005)

  • Effectiveness
    None (for multiple sclerosis)
  • Effectiveness
    Major (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Provigil continues to be a very effective treatment for fatigue, I would not be able to stay awake without it.
Cost: < $25 monthly

Jan 25, 2012 (Started Oct 14, 2005)

  • Effectiveness
    Major (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: The increased dosage helps to shorten how long I sleep, when I sometimes still fall asleep during the day. I also don't fall back to sleep, right after eating breakfast or lunch.
Cost: < $25 monthly

Jul 19, 2009 (Started Oct 14, 2005)

  • Effectiveness
    Major (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Cost: < $25 monthly

Nov 7, 2008 (Started Oct 14, 2005)

  • Effectiveness
    Major (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Provigil has enabled me to stay awake and function all day, without it I fall asleep when I am sitting down longer than 15 minutes. I am still able to nap or rest, even if I just took it and it does not make me nervous or jittery.
Cost: $200+ monthly

  • 1 helpful mark

Jan 15, 2016 (Started Jan 01, 2010)

  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks

Dec 2, 2015 (Started Apr 06, 2006)

  • Effectiveness
    Major (for multiple sclerosis)
  • Effectiveness
    Major (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Provigil gives me energy to do my daily chores i.e. fixing meals, laundry, showering. I have no side efffects! The generic modafinil is the same as Provigil and much less expensive!

  • 0 helpful marks
Last updated:
Showing 3 of 131 patient evaluations for Modafinil