What is Modafinil?

Category: Prescription Drugs

Most popular types: Provigil Alertec Modiodal Show all

false

Modafinil is stimulant used to improve wakefulness in patients narcolepsy and shift work sleep disorder or as an adjunctive therapy for obstructive sleep apnea. It may also be used for attention-deficit/hyperactivity disorder and to treat fatigue in MS and other disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fatigue 1,529 715
Multiple sclerosis 918 434
Excessive daytime sleepiness (somnolence) 520 361
Narcolepsy 106 58
Brain fog 81 53

Show all 93 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 73
Moderate 158
Mild 261
None 638

Commonly reported side effects and conditions associated with Modafinil

Side effect Patients
Jittery feeling 58
Headaches 57
Dry mouth 51
Anxious mood 36
Tachycardia (fast heart rate) 31
Irritability 22

Show all 161 reported side effects

Dosages

Based on patients currently taking Modafinil

Dosage Patients
200 mg daily 112
100 mg daily 67
400 mg daily 37
200 mg twice daily 17
200mg as needed 13
100 mg twice daily 8
100mg as needed 8
400 mg twice daily 5
150 mg daily 3
300 mg daily 3

See all 29 dosages

Why patients stopped taking Modafinil

Multiple reasons could be selected

Reason Patients
Did not seem to work 288
Other 205
Side effects too severe 199
Expense 182
Doctor's advice 118
Change in health plan coverage 92
Personal research 36
Course of treatment ended 19
See all 883 patients who've stopped taking Modafinil

Duration

Currently taking Modafinil

Duration Patients
Less than 1 month 1
1 - 6 months 12
6 months - 1 year 12
1 - 2 years 14
2 - 5 years 58
5 - 10 years 108
10 years or more 89

Stopped taking Modafinil

Duration Patients
Less than 1 month 131
1 - 6 months 183
6 months - 1 year 127
1 - 2 years 145
2 - 5 years 197
5 - 10 years 76
10 years or more 26
Adherence
Adherence Evaluations
Always 768
Usually 227
Sometimes 98
Never taken as prescribed 37
Burden
Burden Evaluations
Very hard to take 36
Somewhat hard to take 65
A little hard to take 142
Not at all hard to take 887
Cost per month
Cost per month Evaluations
$200+ 89
$100-199 53
$50-99 139
$25-49 166
< $25 334
Not specified 349

What people switch to and from

Patients started taking Modafinil after stopping:

Treatment Patients
Methylphenidate (Ritalin) 27
Armodafinil (Nuvigil) 19
Amphetamine-Dextroamphetamine (Adderall) 16
Amantadine (Symmetrel) 10
Pemoline 2

Show all 14 treatments patients report switching from

Patients stopped taking Modafinil and switched to:

Treatment Patients
Armodafinil (Nuvigil) 33
Amphetamine-Dextroamphetamine (Adderall) 27
Methylphenidate (Ritalin) 9
Dextroamphetamine (Dexedrine) 4
Amantadine (Symmetrel) 2

Show all 9 treatments patients report switching to

Last updated:

133 patient evaluations for Modafinil

Apr 20, 2009 (Started Apr 16, 2009)

  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    Moderate (stiffness in neck, irritability, headaches, dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Do not take too close to bedtime - or you will not sleep. Does give some help with daytime drowsiness.
Cost: < $25 monthly
Side effects: dry mouth, irritability, headaches, stiffness in neck

  • 2 helpful marks

Apr 24, 2009 (Started Nov 01, 2005)

  • Effectiveness
    Moderate (for fatigue)
  • Side effects
    Severe (sleep problems, stiffness in neck, jittery feeling, irritability, dry mouth, anxious mood)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 100 mg Daily
Advice & Tips: take if you need it and leave it alone if you don't
Cost: $50-99 monthly
Side effects: dry mouth, jittery feeling, sleep problems, anxious mood, irritability, stiffness in neck

  • 2 helpful marks

May 26, 2011 (Started Jul 18, 2009)

  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Effectiveness
    Moderate (for obstructive sleep apnea)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: Got my life back. When combined with SSRI's was by far the best treatment for depression I have ever seen. It should be considered for trials for depression.....
Cost: $25-49 monthly
Side effects: hot flashes

Jun 19, 2010 (Started Jul 18, 2009)

  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Effectiveness
    Major (for obstructive sleep apnea)
  • Side effects
    Mild (hot flashes)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: Life with out Modafinil is very ordinary. I was first diagnosed with depression two year before having a sleep study and OSA and somnolence was discovered. I wonder now if the depression was just a result of these two conditions. I am on 150mg of Setraline for the depression and since being on both that and 200mg of modafinil, I have my life back. I once could not walk past the bed and not want to get in. I often fell aslep if I lay down on the floor to play with my children. I was a zombie. Great drug. Worth every cent for my issues.
Cost: $25-49 monthly
Side effects: hot flashes

  • 2 helpful marks
Last updated:
Showing 3 of 133 patient evaluations for Modafinil