What is Modafinil?

Category: Prescription Drugs

Most popular types: Provigil Alertec Modiodal Show all

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Modafinil is stimulant used to improve wakefulness in patients narcolepsy and shift work sleep disorder or as an adjunctive therapy for obstructive sleep apnea. It may also be used for attention-deficit/hyperactivity disorder and to treat fatigue in MS and other disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fatigue 1,532 719
Multiple sclerosis 918 437
Excessive daytime sleepiness (somnolence) 523 365
Narcolepsy 106 57
Brain fog 81 53

Show all 85 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 73
Moderate 157
Mild 262
None 643

Commonly reported side effects and conditions associated with Modafinil

Side effect Patients
Jittery feeling 59
Headaches 56
Dry mouth 51
Anxious mood 36
Tachycardia (fast heart rate) 31
Irritability 22

Show all 149 reported side effects

Dosages

Based on patients currently taking Modafinil

Dosage Patients
200 mg daily 93
100 mg daily 59
400 mg daily 28
200 mg twice daily 16
100mg as needed 8
200mg as needed 8
100 mg twice daily 7
400 mg twice daily 6
150 mg daily 4
300 mg daily 3

See all 28 dosages

Why patients stopped taking Modafinil

Multiple reasons could be selected

Reason Patients
Did not seem to work 289
Other 206
Side effects too severe 200
Expense 182
Doctor's advice 118
Change in health plan coverage 92
Personal research 36
Course of treatment ended 19
See all 885 patients who've stopped taking Modafinil

Duration

Currently taking Modafinil

Duration Patients
Less than 1 month 1
1 - 6 months 10
6 months - 1 year 9
1 - 2 years 15
2 - 5 years 53
5 - 10 years 87
10 years or more 77

Stopped taking Modafinil

Duration Patients
Less than 1 month 132
1 - 6 months 183
6 months - 1 year 128
1 - 2 years 145
2 - 5 years 197
5 - 10 years 77
10 years or more 26
Adherence
Adherence Evaluations
Always 773
Usually 227
Sometimes 98
Never taken as prescribed 37
Burden
Burden Evaluations
Very hard to take 36
Somewhat hard to take 65
A little hard to take 142
Not at all hard to take 892
Cost per month
Cost per month Evaluations
$200+ 89
$100-199 53
$50-99 140
$25-49 166
< $25 336
Not specified 351

What people switch to and from

Patients started taking Modafinil after stopping:

Treatment Patients
Methylphenidate (Ritalin) 27
Armodafinil (Nuvigil) 19
Amphetamine-Dextroamphetamine (Adderall) 16
Amantadine (Symmetrel) 11
Dextroamphetamine (Dexedrine) 2

Show all 15 treatments patients report switching from

Patients stopped taking Modafinil and switched to:

Treatment Patients
Armodafinil (Nuvigil) 32
Amphetamine-Dextroamphetamine (Adderall) 29
Methylphenidate (Ritalin) 9
Dextroamphetamine (Dexedrine) 4
Amantadine (Symmetrel) 2

Show all 9 treatments patients report switching to

Last updated:

133 patient evaluations for Modafinil

May 19, 2018 (Started Aug 31, 2010)

  • Effectiveness
    None (for excessive daytime sleepiness (somnolence))
  • Effectiveness
    None (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: NOW THAT I HAVE PD AND SENSORY NEUROPATHY I AM ALWAY S TIRED AND IN PAIN.
Cost: $25-49 monthly

Dec 28, 2016 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: $25-49 monthly

Aug 11, 2015 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I GET TIRED EVERYDAY STILL, BUT I DON'T ALWAYS NAP LIKE I USED TO.
Cost: $25-49 monthly

Aug 11, 2014 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: It is still working well, as my napping and dozing has decreased quite a bit. Thumbs Up to Provigil!!
Cost: $25-49 monthly

Jul 14, 2012 (Started Aug 31, 2010)

  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: DEFINITELY HELPS SO I'M NOT ALWAYS DOZING OFF.
Cost: $25-49 monthly

Dec 1, 2011 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: The insurance company stopped paying for Provogil. It took a month to get it approved.
Cost: $25-49 monthly

Nov 15, 2011 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I get very tired and could sleep all day. I was on Provigil, but then the insurance company denied refills. It took a month to get the insurance company to approve it.
Cost: $25-49 monthly

Aug 1, 2011 (Started Aug 31, 2010)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I was on Provigil because e I was sleeping all the time. Then insurance company denied my prescription. It took one month to get me back on it.
Cost: $25-49 monthly

Aug 1, 2010 (Started Aug 31, 2010)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Without this medication, I sleep on & off all day, and I am constantly weak & tired. I don't feel like doing anything. My insurance company stopped paying for it for 1 month while I appealed their decision. I won the appeal and I thank God I was able to take it again.
Cost: $25-49 monthly

  • 1 helpful mark

Feb 21, 2018 (Started Apr 01, 2009)

  • Effectiveness
    Moderate (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: One pill keeps me awake and alert until mid-day. That's what I expected. It's easy to adhere to and does't cause me any side affects.

  • 0 helpful marks

Sep 30, 2017 (Started Sep 01, 2009)

  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    Mild (insomnia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: At tne end of 2016, I quit working at UTC full time. When the days get shorter in August, something happens to my mood. This year was different because I didn't have to work. The Psych Dr said to try adding 30 mg of Cymbalta later in the day to get rid of the "zaps". This happens because the brain needs more antidepressant. I also added 200 mg modafinil per day. It has been 1 week.
Cost: < $25 monthly

Mar 6, 2017 (Started Sep 01, 2009)

  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    Mild (insomnia)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: The jury is still out. If I was working full-time, perhaps I would need 300 mg/day. I think the key is to not take long naps that end up keeping you up until 2am.
Cost: < $25 monthly

Sep 23, 2016 (Started Sep 01, 2009)

  • Effectiveness
    Can't tell (for excessive daytime sleepiness (somnolence))
  • Side effects
    Mild (insomnia)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: I am starting at 100mg/day. Maybe the Rytary helps with wakefulness? Must wait until the dead of winter.
Cost: < $25 monthly

Feb 1, 2015 (Started Sep 01, 2009)

  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Side effects
    Mild (insomnia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: I take 300mg/day.
Cost: < $25 monthly

Nov 8, 2014 (Started Sep 01, 2009)

  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Side effects
    Mild (insomnia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Started on Nov 1. 2014 this season. 300mg modafinil. Yes, I n case I start to doubt if the drug is helpful--it is. Caffeine does not help me feel better. More sleep does not help me feel more lively.
Cost: < $25 monthly

Feb 22, 2014 (Started Sep 01, 2009)

  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Side effects
    Mild (insomnia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I have been take this seasonally. Note that the "plan" price at Express Scripts was about $1000 for 90 day supply (any dosage); my insurance price was about $100. Now, my insurance price for the same 90 day supply is $20 and I think it's because of generic/patent status.
Cost: < $25 monthly

Apr 18, 2013 (Started Sep 01, 2009)

  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    Moderate (insomnia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I still take this in the fall (when the days are just starting to get short) like the end of August. I then stop in March. I have used Nuvigil or Provigil. If I decrease dose, i am sleepy during day. If i maintain does, it is very easy to stay up until 1am.
Cost: $25-49 monthly

Aug 23, 2011 (Started Sep 01, 2009)

  • Effectiveness
    Moderate (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Helps with sleepiness during the day.
Cost: $25-49 monthly

May 13, 2010 (Started Sep 01, 2009)

  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I liked Provigil. It counteracted the sleepiness from Cymbalta prescribed by the psychatrist, but the dosage wasn't enough for sleepiness from Mirapex prescribed by the neurologist. Medco wouldn't up my dosage.
Cost: $25-49 monthly

May 2, 2010 (Started Sep 01, 2009)

  • Effectiveness
    Major (for excessive daytime sleepiness (somnolence))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: This works. My Rx ran out, then Medco wouldn't allow me300mg/day. then the dr. subscribes a new drug Nuvigil for250g/day. Note that Provigil will go generic soon, and the cost will decrease.
Cost: $25-49 monthly

  • 2 helpful marks
Last updated:
Showing 3 of 133 patient evaluations for Modafinil