What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

false

See also: Lidocaine-prilocaine-meloxicam-lamotrigine cream

Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar Disorder 1,359 780
Epilepsy 1,070 503
Bipolar II Disorder 683 418
Bipolar I Disorder 412 258
Depressed mood 150 99
Borderline Personality Disorder 141 89

Show all 216 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 238
Moderate 390
Mild 546
None 866

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Dizziness 67
Headaches 65
Weight gain 63
Nausea 48
Insomnia 45
Problems concentrating 45

Show all 509 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 142
100 mg daily 91
150 mg daily 65
25 mg daily 61
50 mg daily 45
300 mg daily 44
200 mg twice daily 44
100 mg twice daily 40
400 mg daily 38
150 mg twice daily 27

See all 68 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 410
Did not seem to work 378
Doctor's advice 248
Other 183
Expense 63
Personal research 53
Course of treatment ended 39
Change in health plan coverage 32
See all 946 patients who’ve stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 9
1 - 6 months 61
6 months - 1 year 82
1 - 2 years 133
2 - 5 years 183
5 - 10 years 179
10 years or more 104

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 196
1 - 6 months 226
6 months - 1 year 152
1 - 2 years 129
2 - 5 years 158
5 - 10 years 85
10 years or more 16
Adherence
Adherence Evaluations
Always 1660
Usually 266
Sometimes 44
Never taken as prescribed 70
Burden
Burden Evaluations
Very hard to take 90
Somewhat hard to take 186
A little hard to take 339
Not at all hard to take 1425
Cost per month
Cost per month Evaluations
$200+ 42
$100-199 48
$50-99 64
$25-49 113
< $25 941
Not specified 832

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 77
Quetiapine (Seroquel) 43
Divalproex sodium (Depakote) 42
Aripiprazole (Abilify) 36
Bupropion (Wellbutrin XL) 18

Show all 52 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 35
Quetiapine (Seroquel) 19
Aripiprazole (Abilify) 18
Divalproex sodium (Depakote) 11
Levetiracetam (Keppra) 8

Show all 51 treatments patients report switching to

Last updated:

138 patient evaluations for Lamotrigine

1,549 members have decided to share their profiles only with other members of PatientsLikeMe.

Christina22222
Portrait default thumb
Christina22222
Data Quality: 3 stars
  • Gender: F
  • Age: 45
Condition: TBI 3 additional condition(s)
Quality of life:
  • Mental: None
  • Physical: Mild
I am: vg
I have:
TBI

See Christina22222's full Lamotrigine history

May 20, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for Seizures)
  • Effectiveness
    Can’t tell (for Epilepsy)
  • Side effects
    Severe (Loss of balance)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Twice daily
Advice & Tips: I could barely walk when my dose got up to 2 tablets twice a day.
Cost: $25-49 monthly

Feb 5, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for Seizures)
  • Effectiveness
    Slight (for Epilepsy)
  • Side effects
    Severe (Loss of balance)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 50 mg Twice daily
Cost: $25-49 monthly

  • 0 helpful marks
COOPERATI
22007 thumb
COOPERATI
Gender: M
Data Quality: 2 stars
Depression: 3
Mania: 2
Emotional: 4
Anxiety: 2
Compulsion: 2
External Stress: Overwhelming
43 M
Function: Low
Distress: High
I am: vb
I have:
Schizophrenia

See COOPERATI's full Lamotrigine history

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Major (for Bipolar rapid cycling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg All the time (24/7)

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Major (for Major Depressive Disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Effectiveness
    Major (for Bipolar rapid cycling)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg All the time (24/7)

  • 0 helpful marks
zoomer
60535 thumb
zoomer
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 1
Emotional: 1
Anxiety: 1
Compulsion: 0
External Stress: Moderate
61 F
Function: High
Distress: Low
I am: g
I have:
Bipolar I

See zoomer's full Lamotrigine history

Feb 6, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar I Disorder)
  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it. I have been taking 400mg since 2006.Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIG time. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Nov 29, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar I Disorder)
  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: I am on a high dose. (400mg a day) I think that is notable since some evaluations of this medication are negative but that seems to be people taking very small doses. Not even therapeutic level ?
Cost: < $25 monthly

Apr 6, 2011 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIGtime. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Oct 25, 2010 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it.
Cost: < $25 monthly

Oct 24, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal continues to work as an effective mood stabilizer, my last depressive episode due to med changes was not severe as episodes before Lamictal. No side effects at this high dose either.
Cost: < $25 monthly

Aug 13, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Given time all negative side effects I may have experienced have disappeared. This medication is an effective mood stabilizer in my regime of meds.

Jul 26, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Cost: < $25 monthly

  • 2 helpful marks
Last updated:
Showing 3 of 138 patient evaluations for Lamotrigine