What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar Disorder 1,330 761
Epilepsy 1,068 499
Bipolar II Disorder 667 401
Bipolar I Disorder 410 253
Depressed mood 146 97
Borderline Personality Disorder 141 90

Show all 215 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 233
Moderate 384
Mild 536
None 843

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Dizziness 67
Headaches 64
Weight gain 62
Nausea 48
Insomnia 45
Problems concentrating 45

Show all 504 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 133
100 mg daily 93
150 mg daily 60
25 mg daily 51
300 mg daily 47
200 mg twice daily 42
50 mg daily 41
400 mg daily 39
100 mg twice daily 37
150 mg twice daily 27

See all 69 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 401
Did not seem to work 374
Doctor's advice 246
Other 182
Expense 61
Personal research 52
Course of treatment ended 37
Change in health plan coverage 32
See all 932 patients who’ve stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 12
1 - 6 months 52
6 months - 1 year 82
1 - 2 years 128
2 - 5 years 174
5 - 10 years 175
10 years or more 102

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 193
1 - 6 months 224
6 months - 1 year 150
1 - 2 years 127
2 - 5 years 155
5 - 10 years 83
10 years or more 16
Adherence
Adherence Evaluations
Always 1623
Usually 263
Sometimes 43
Never taken as prescribed 67
Burden
Burden Evaluations
Very hard to take 88
Somewhat hard to take 183
A little hard to take 333
Not at all hard to take 1392
Cost per month
Cost per month Evaluations
$200+ 41
$100-199 48
$50-99 62
$25-49 112
< $25 925
Not specified 808

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 74
Divalproex sodium (Depakote) 39
Quetiapine (Seroquel) 39
Aripiprazole (Abilify) 35
Bupropion (Wellbutrin XL) 16

Show all 52 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 32
Quetiapine (Seroquel) 19
Aripiprazole (Abilify) 17
Divalproex sodium (Depakote) 11
Oxcarbazepine (Trileptal) 8

Show all 50 treatments patients report switching to

Last updated:

137 patient evaluations for Lamotrigine

1,520 members have decided to share their profiles only with other members of PatientsLikeMe.

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Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: Moderate
61 F
Function: High
Distress: Low
I am: g
I have:
Bipolar I

See zoomer's full Lamotrigine history

Feb 6, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar I Disorder)
  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it. I have been taking 400mg since 2006.Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIG time. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Nov 29, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar I Disorder)
  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: I am on a high dose. (400mg a day) I think that is notable since some evaluations of this medication are negative but that seems to be people taking very small doses. Not even therapeutic level ?
Cost: < $25 monthly

Apr 6, 2011 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIGtime. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Oct 25, 2010 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it.
Cost: < $25 monthly

Oct 24, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal continues to work as an effective mood stabilizer, my last depressive episode due to med changes was not severe as episodes before Lamictal. No side effects at this high dose either.
Cost: < $25 monthly

Aug 13, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Given time all negative side effects I may have experienced have disappeared. This medication is an effective mood stabilizer in my regime of meds.

Jul 26, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Cost: < $25 monthly

  • 2 helpful marks
Christina22222
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Christina22222
Data Quality: 3 stars
  • Gender: F
  • Age: 45
Condition: TBI 3 additional condition(s)
Quality of life:
  • Mental: None
  • Physical: Mild
I am: vg
I have:
TBI

See Christina22222's full Lamotrigine history

Feb 5, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for Seizures)
  • Effectiveness
    Slight (for Epilepsy)
  • Side effects
    Severe (Loss of balance)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 50 mg Twice daily
Cost: $25-49 monthly

  • 0 helpful marks
charkimber
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charkimber
Gender: F
Data Quality: 3 stars
Depression: 3
Mania: 1
Emotional: 3
Anxiety: 2
Compulsion: 3
External Stress: Severe
57 F
Function: Low
Distress: Moderate
I am: g
I have:
Bipolar II

See charkimber's full Lamotrigine history

Jan 18, 2017 (Started Jul 01, 2009)

  • Effectiveness
    Major (for Bipolar II Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Don't go off without talking to doctor. I came out of the fog after starting this medication.

  • 0 helpful marks
Last updated:
Showing 3 of 137 patient evaluations for Lamotrigine