What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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See also: Lidocaine-prilocaine-meloxicam-lamotrigine cream

Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar disorder 1,542 892
Epilepsy 1,104 529
Bipolar II disorder 776 468
Bipolar I disorder 457 285
Depressed mood 162 108
Major depressive disorder 158 125

Show all 204 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 270
Moderate 416
Mild 604
None 974

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Weight gain 77
Dizziness 70
Headaches 69
Rashes (redness, swelling) 52
Nausea 50
Fatigue 47

Show all 512 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 140
100 mg daily 89
25 mg daily 56
150 mg daily 49
300 mg daily 46
200 mg twice daily 37
400 mg daily 36
100 mg twice daily 34
50 mg daily 31
150 mg twice daily 22

See all 63 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 461
Did not seem to work 406
Doctor's advice 273
Other 200
Expense 68
Personal research 53
Course of treatment ended 43
Change in health plan coverage 35
See all 1039 patients who've stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 2
1 - 6 months 29
6 months - 1 year 60
1 - 2 years 97
2 - 5 years 189
5 - 10 years 193
10 years or more 105

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 239
1 - 6 months 239
6 months - 1 year 156
1 - 2 years 141
2 - 5 years 170
5 - 10 years 93
10 years or more 17
Adherence
Adherence Evaluations
Always 1853
Usually 284
Sometimes 50
Never taken as prescribed 77
Burden
Burden Evaluations
Very hard to take 96
Somewhat hard to take 205
A little hard to take 369
Not at all hard to take 1594
Cost per month
Cost per month Evaluations
$200+ 42
$100-199 49
$50-99 65
$25-49 121
< $25 1050
Not specified 937

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 100
Divalproex sodium (Depakote) 49
Quetiapine (Seroquel) 48
Aripiprazole (Abilify) 43
Bupropion (Wellbutrin XL) 24

Show all 54 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 37
Aripiprazole (Abilify) 27
Quetiapine (Seroquel) 21
Divalproex sodium (Depakote) 16
Lurasidone (Latuda) 14

Show all 60 treatments patients report switching to

Last updated:

140 patient evaluations for Lamotrigine

Dec 30, 2017 (Started Feb 15, 2015)

  • Effectiveness
    Major (for bipolar mixed episodes)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

May 20, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for seizures)
  • Effectiveness
    Can't tell (for epilepsy)
  • Side effects
    Severe (loss of balance)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Twice daily
Advice & Tips: I could barely walk when my dose got up to 2 tablets twice a day.
Cost: $25-49 monthly

Feb 5, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for seizures)
  • Effectiveness
    Slight (for epilepsy)
  • Side effects
    Severe (loss of balance)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 50 mg Twice daily
Cost: $25-49 monthly

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Major (for bipolar rapid cycling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Major (for depressed mood)
  • Effectiveness
    Major (for bipolar rapid cycling)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg All the time (24/7)

  • 0 helpful marks
Last updated:
Showing 3 of 140 patient evaluations for Lamotrigine