What is Selegiline?

Category: Prescription Drugs

Most popular types: Zelapar Emsam Eldepryl Show all

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See also: Xilopar

Selegiline is an antidepressant and anti-Parkinson's agent. Orally it is used as an adjunct to levodopa/carbidopa therapy for Parkinson's disease; transdermally it is used for major depressive disorder. It has also been used for ADHD; negative symptoms of schizophrenia and extrapyramidal symptoms.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 362 142
Depressed mood 39 38
Major depressive disorder 18 19
Stiffness/spasticity 12 2
Fatigue 7 1

Show all 37 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 33
Moderate 25
Mild 36
None 107

Commonly reported side effects and conditions associated with Selegiline

Side effect Patients
Insomnia 8
Difficulty falling asleep 4
Drowsiness 4
Nausea 4
Diarrhea 3
Dietary restrictions 3

Show all 78 reported side effects

Dosages

Based on patients currently taking Selegiline

Dosage Patients
5 mg twice daily 21
10 mg daily 13
5 mg daily 11
2.5 mg daily 4
1.25 mg daily 2
0.375 mg daily 1
6 mg daily 1
12 mg/24 hr daily 1
10 mg twice daily 1
5 mg four times daily 1

See all 14 dosages

Why patients stopped taking Selegiline

Multiple reasons could be selected

Reason Patients
Did not seem to work 75
Doctor's advice 63
Side effects too severe 47
Other 28
Personal research 13
Expense 9
Course of treatment ended 7
Change in health plan coverage 4
See all 182 patients who've stopped taking Selegiline

Duration

Currently taking Selegiline

Duration Patients
1 - 6 months 2
6 months - 1 year 4
1 - 2 years 10
2 - 5 years 12
5 - 10 years 23
10 years or more 9

Stopped taking Selegiline

Duration Patients
Less than 1 month 30
1 - 6 months 40
6 months - 1 year 25
1 - 2 years 37
2 - 5 years 34
5 - 10 years 13
10 years or more 7
Adherence
Adherence Evaluations
Always 158
Usually 26
Sometimes 2
Never taken as prescribed 15
Burden
Burden Evaluations
Very hard to take 10
Somewhat hard to take 15
A little hard to take 30
Not at all hard to take 146
Cost per month
Cost per month Evaluations
$200+ 4
$100-199 2
$50-99 22
$25-49 28
< $25 67
Not specified 78

What people switch to and from

Patients started taking Selegiline after stopping:

Treatment Patients
Rasagiline (Azilect) 9
Bupropion (Wellbutrin XL) 3
Duloxetine (Cymbalta) 3
Carbidopa-Levodopa (Sinemet) 2
Pramipexole (Mirapex) 2

Show all 20 treatments patients report switching from

Patients stopped taking Selegiline and switched to:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 4
Rasagiline (Azilect) 2
Tranylcypromine (Parnate) 2
Amantadine (Symmetrel) 1
Amphetamine-Dextroamphetamine (Adderall) 1

Show all 15 treatments patients report switching to

Last updated:

28 patient evaluations for Selegiline

Jun 25, 2014 (Started Jan 04, 2007)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Mild (skin irritation)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 9 mg/24 hr Daily
Advice & Tips: Be careful with processed or preserved(like vinegar, red wine)
Cost: $50-99 monthly
Side effects: skin irritation

Dec 21, 2010 (Started Jan 04, 2007)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Mild (skin irritation)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg/24 hr All the time (24/7)
Cost: < $25 monthly
Side effects: skin irritation

Feb 18, 2009 (Started Jan 04, 2007)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg/24 hr All the time (24/7)
Cost: < $25 monthly
Side effects: skin irritation

Jan 17, 2009 (Started Jan 04, 2007)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg/24 hr All the time (24/7)
Cost: < $25 monthly
Side effects: skin irritation

Aug 19, 2008 (Started Jan 04, 2007)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg/24 hr All the time (24/7)
Advice & Tips: stick with it
Cost: < $25 monthly
Side effects: skin irritation

  • 1 helpful mark

Jan 15, 2014 (Started May 01, 2005)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Effectiveness
    Can't tell (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: Daily

  • 0 helpful marks

Jan 9, 2014 (Started Oct 07, 2008)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

Feb 13, 2012 (Started Oct 07, 2008)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 28 patient evaluations for Selegiline