What is Sertraline?

Category: Prescription Drugs

Most popular types: Zoloft Apo-Sertraline Sertra Show all

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Sertraline, a selective serotonin reuptake inhibitor (SSRI) antidepressant, is used in the treatment of major depression, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and social anxiety disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 1,798 887
Major depressive disorder 1,570 849
Post-traumatic stress disorder 719 425
Anxious mood 489 214
Panic disorder 314 196
Persistent depressive disorder (dysthymia) 212 155

Show all 191 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 247
Moderate 441
Mild 519
None 805

Commonly reported side effects and conditions associated with Sertraline

Side effect Patients
Weight gain 125
Dry mouth 80
Sex drive (libido) decreased 73
Fatigue 70
Loss of sex drive (libido) 69
Nausea 48

Show all 387 reported side effects

Dosages

Based on patients currently taking Sertraline

Dosage Patients
100 mg daily 175
50 mg daily 140
200 mg daily 74
150 mg daily 67
25 mg daily 50
100 mg twice daily 27
75 mg daily 11
50 mg twice daily 10
25 mg twice daily 4
300 mg daily 4

See all 41 dosages

Why patients stopped taking Sertraline

Multiple reasons could be selected

Reason Patients
Did not seem to work 733
Side effects too severe 490
Doctor's advice 421
Other 279
Course of treatment ended 93
Personal research 82
Expense 60
Change in health plan coverage 45
See all 1537 patients who've stopped taking Sertraline

Duration

Currently taking Sertraline

Duration Patients
Less than 1 month 3
1 - 6 months 36
6 months - 1 year 59
1 - 2 years 107
2 - 5 years 142
5 - 10 years 136
10 years or more 129

Stopped taking Sertraline

Duration Patients
Less than 1 month 260
1 - 6 months 322
6 months - 1 year 247
1 - 2 years 229
2 - 5 years 268
5 - 10 years 135
10 years or more 87
Adherence
Adherence Evaluations
Always 1575
Usually 291
Sometimes 70
Never taken as prescribed 76
Burden
Burden Evaluations
Very hard to take 81
Somewhat hard to take 135
A little hard to take 298
Not at all hard to take 1498
Cost per month
Cost per month Evaluations
$200+ 8
$100-199 20
$50-99 19
$25-49 76
< $25 1014
Not specified 875

What people switch to and from

Patients started taking Sertraline after stopping:

Treatment Patients
Fluoxetine (Prozac) 89
Citalopram (Celexa) 70
Bupropion (Wellbutrin XL) 51
Venlafaxine (Effexor XR) 41
Duloxetine (Cymbalta) 33

Show all 52 treatments patients report switching from

Patients stopped taking Sertraline and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 66
Bupropion (Wellbutrin XL) 56
Duloxetine (Cymbalta) 54
Fluoxetine (Prozac) 47
Escitalopram (Lexapro) 45

Show all 42 treatments patients report switching to

Last updated:

145 patient evaluations for Sertraline

Oct 2, 2017 (Started Feb 16, 2014)

  • Effectiveness
    Moderate (for mild depression)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

Aug 1, 2015 (Started Feb 16, 2014)

  • Effectiveness
    Major (for mild depression)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: I found that taking Sertraline was much more effective than any other Anti Depressants i have taken. My reason for stopping was to try and ascertain whether or not it was causing another Medical disorder, NIGHT SWEATING. IF the Night Sweating persists without the Sertraline i will probably go back to Sertraline
Cost: < $25 monthly

Feb 4, 2015 (Started Feb 16, 2014)

  • Effectiveness
    Moderate (for mild depression)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily

  • 1 helpful mark

Feb 15, 2017 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: No changes
Cost: < $25 monthly

Nov 30, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: No changes since 3/20/15
Cost: < $25 monthly

Aug 2, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Moderate (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

May 9, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Apr 24, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 1, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Moderate (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Oct 21, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Mild (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 20, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: My digestive problems have been resolved. I have no other conditions that would lead a doctor to think I had anything seriously wrong with me. I now take 150 mgs of Zoloft. I take it every day with no problem.
Cost: < $25 monthly

Feb 4, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: The only problem I've had is bad diarhea, from starting to take it again after not having been on it for about a month. This was due to a change in providers.
Cost: < $25 monthly

Oct 28, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Sep 10, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: I am now taking 200 mg a day (4 50mg tabs a day). I have no problems with taking it at all.
Cost: < $25 monthly

Jun 2, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Mild (sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

May 8, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Jan 17, 2011 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: it has had no impact on my lifestyle at all. It is a pill taken once a day.
Cost: < $25 monthly

  • 0 helpful marks

Feb 12, 2017 (Started Jul 01, 1982)

  • Effectiveness
    None (for post-traumatic stress disorder)
  • Effectiveness
    None (for panic disorder)
  • Effectiveness
    None (for major depressive disorder)
  • Effectiveness
    None (for depressed mood)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Somewhat hard to take
Dosage: Yearly
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 145 patient evaluations for Sertraline