What is Desvenlafaxine?

Category: Prescription Drugs

Most Popular Types: Pristiq, Exsira

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Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI). It is an extended release formulation believed to treat depression by affecting the levels of serotonin and norepinephrine, two neurotransmitters associated with depression.

Reported purpose & perceived effectiveness

Purpose
Patients
Patients with evaluations
Perceived effectiveness

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects of Desvenlafaxine

Severe
45
Moderate
39
Mild
48
None
76

Commonly reported side effects, conditions, and hospitalizations associated with Desvenlafaxine

Patients
14
Patients
13
Patients
12
Patients
10
Patients
9
Patients
9

Show all 111 reported side effects

Dosages

Most common dosages (by patients currently taking Desvenlafaxine)
Dosage
50 mg daily
Patients
224
Dosage
100 mg daily
Patients
142
Dosage
150 mg daily
Patients
15
Dosage
200 mg daily
Patients
13
Dosage
1 mg daily
Patients
5
Dosage
300 mg daily
Patients
3
Dosage
1 other daily
Patients
2
Dosage
25 mg daily
Patients
2
Dosage
75 mg daily
Patients
2
Dosage
2 mg daily
Patients
1

Dosages based on patients currently taking Desvenlafaxine.

Why Patients Stopped Taking Desvenlafaxine (multiple reasons could be selected)
Reason
Did not seem to work
Patients
70
Reason
Side effects too severe
Patients
58
Reason
Expense
Patients
33
Reason
Doctor's advice
Patients
33
Reason
Other
Patients
29
Reason
Personal research
Patients
7
Reason
Change in health plan coverage
Patients
7
Reason
Course of treatment ended
Patients
5
Reason
Not indicated
Patients
3
See all 175 patients who’ve stopped taking Desvenlafaxine

Duration

Currently Taking Desvenlafaxine
Duration
Patients
Duration
0-1 month
Patients
1
Duration
1-3 months
Patients
3
Duration
3-6 months
Patients
2
Duration
6 months-1 year
Patients
4
Duration
1-2 years
Patients
7
Duration
2 years or more
Patients
46
Stopped Taking Desvenlafaxine
Duration
Patients
Duration
0-1 month
Patients
23
Duration
1-3 months
Patients
34
Duration
3-6 months
Patients
23
Duration
6 months-1 year
Patients
37
Duration
1-2 years
Patients
29
Duration
2 years or more
Patients
20

Adherence


Always
Patients
176
85%
Usually
Patients
23
11%
Sometimes
Patients
3
1%
Never taken as prescribed
Patients
6
3%

Burden


Very hard to take
Patients
14
7%
Somewhat hard to take
Patients
15
7%
A little hard to take
Patients
29
14%
Not at all hard to take
Patients
150
72%

Cost per month


Cost per month
$200+
Patients
5
2%
Cost per month
$100-199
Patients
10
5%
Cost per month
$50-99
Patients
25
12%
Cost per month
$25-49
Patients
38
18%
Cost per month
< $25
Patients
53
25%
Cost per month
Not specified
Patients
77
37%

What people switch to and from

Patients started taking Desvenlafaxine after stopping:
Treatment name(s)
Venlafaxine (Effexor XR, Effexor, Venlafaxine XR…)
Patients
6
Treatment name(s)
Duloxetine (Cymbalta, Cymgen, Yentreve…)
Patients
4
Treatment name(s)
Escitalopram (Lexapro, Cipralex, Lexamil…)
Patients
4
Treatment name(s)
Fluoxetine (Prozac, Lovan, Fluxene…)
Patients
4
Treatment name(s)
Bupropion (Wellbutrin XL, Wellbutrin, Wellbutrin SR…)
Patients
2

See all 13 treatments patients report switching from

Patients stopped taking Desvenlafaxine and switched to:
Treatment name(s)
Duloxetine (Cymbalta, Cymgen, Yentreve…)
Patients
4
Treatment name(s)
Venlafaxine (Effexor XR, Effexor, Venlafaxine XR…)
Patients
4
Treatment name(s)
Citalopram (Celexa, Cipramil, APO-Citalopram…)
Patients
3
Treatment name(s)
Sertraline (Zoloft, Apo-Sertraline, Lustral…)
Patients
3
Treatment name(s)
Fluoxetine (Prozac, Lovan, Fluxene…)
Patients
2

See all 14 treatments patients report switching to

Last updated:

26 patient evaluations for Desvenlafaxine

dmwhite113@gmail.com
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dmwhite113@gmail.com
Gender: F
Data Quality: 1 star
Pain: Little
Fatigue: Little
Sleep: Little
Stiffness: Little
function: None
external_stress: None
Stickman: little
Description:F59y
FM:7y Dx
I am: n
I have:
Fibromyalgia

See dmwhite113@gmail.com's full Desvenlafaxine history

Jul 25, 2015 (Started Mar 15, 2014)

  • Effectiveness
    Can’t tell (for Major Depressive Disorder)
  • Side Effects
    Moderate (Generalized Anxiety Disorder, Agoraphobia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I DID NOT REALLY REALIZE THE ANXIETY AND AGORAPHOBIA WAS BECAUSE OF THE PRISTIQ UNTIL RECENTLY.

  • 0 helpful marks
zoomer
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zoomer
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: Moderate
60 F
Function: High
Distress: Low
I am: g
I have:
Bipolar I

See zoomer's full Desvenlafaxine history

Mar 15, 2015 (Started Mar 10, 2010)

  • Effectiveness
    Major (for Depressed mood)
  • Effectiveness
    Major (for Bipolar I Disorder)
  • Side Effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

Apr 6, 2011 (Started Mar 10, 2010)

  • Effectiveness
    Major (for Bipolar I Disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side Effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: The efficacy for Bipolar1 is major because I am experiencing a significant decrease in the depressive episodes.(not having) Therefore, what a major wonder this anti depressant is doing so far. especially, because life circumstances kind of warrant depression..HA! and because I have had no side effects. I switched straight across from 120mg Cymbalta to the 100mg of Pristiq overnight. Last summer when starting Pristiq I attributed many side effects to the med. Maybe looking back, I was at a different place physiologically. I know we change and meds stop working or old ones do work that didn't work before. Hope you all find success..
Cost: < $25 monthly

  • 0 helpful marks
arachnoiditis555
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arachnoiditis555
Data Quality: 1 star
  • Gender: M
  • Age: 40
Condition: Arachnoiditis 3 additional condition(s)
Quality of Life:
  • Mental: Moderate
  • Physical: Moderate
I am: n
I have:
Arachnoiditis

See arachnoiditis555's full Desvenlafaxine history

Jun 20, 2014 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Side Effects
    Moderate (Sex drive (libido) decreased)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Advice & Tips: For me, this med worked pretty well for my depression, but it destroyed my libido. I have been off it for about a month, and my libido still isn't the same as it was before I started taking Pristiq. Not even close. I've tried other anti-depressants, and most did have a slight negative impact on my sex drive, however Pristiq has been devastating in that area. I'm wondering if the "old me" will ever return in respect to libido.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 26 patient evaluations for Desvenlafaxine