What is Desvenlafaxine?

Category: Prescription Drugs

Most popular types: Pristiq Exsira

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Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI). It is an extended release formulation believed to treat depression by affecting the levels of serotonin and norepinephrine, two neurotransmitters associated with depression.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 237 166
Major Depressive Disorder 169 116
Anxious mood 89 62
Fibromyalgia 42 33
Bipolar Disorder 21 11
Pain 11 9

Show all 51 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 54
Moderate 65
Mild 85
None 133

Commonly reported side effects and conditions associated with Desvenlafaxine

Side effect Patients
Nausea 12
Weight gain 12
Tiredness increased 11
Sex drive (libido) decreased 10
Increased energy 9
Sedation 8

Show all 126 reported side effects

Dosages

Based on patients currently taking Desvenlafaxine

Dosage Patients
50 mg daily 27
100 mg daily 26
25 mg daily 1
75 mg daily 1
150 mg daily 1
200 mg daily 1
150 mg twice daily 1
300 mg daily 1
1,500 mg daily 1

Why patients stopped taking Desvenlafaxine

Multiple reasons could be selected

Reason Patients
Did not seem to work 83
Side effects too severe 61
Doctor's advice 41
Expense 38
Other 29
Change in health plan coverage 9
Personal research 7
Course of treatment ended 6
See all 195 patients who’ve stopped taking Desvenlafaxine

Duration

Currently taking Desvenlafaxine

Duration Patients
Less than 1 month 1
1 - 6 months 6
6 months - 1 year 3
1 - 2 years 11
2 - 5 years 21
5 - 10 years 17
10 years or more 3

Stopped taking Desvenlafaxine

Duration Patients
Less than 1 month 30
1 - 6 months 62
6 months - 1 year 42
1 - 2 years 34
2 - 5 years 22
5 - 10 years 6
Adherence
Adherence Evaluations
Always 291
Usually 32
Sometimes 3
Never taken as prescribed 11
Burden
Burden Evaluations
Very hard to take 14
Somewhat hard to take 24
A little hard to take 35
Not at all hard to take 264
Cost per month
Cost per month Evaluations
$200+ 7
$100-199 16
$50-99 35
$25-49 57
< $25 102
Not specified 120

What people switch to and from

Patients started taking Desvenlafaxine after stopping:

Treatment Patients
Venlafaxine (Effexor XR) 13
Duloxetine (Cymbalta) 8
Escitalopram (Lexapro) 8
Fluoxetine (Prozac) 8
Sertraline (Zoloft) 5

Show all 19 treatments patients report switching from

Patients stopped taking Desvenlafaxine and switched to:

Treatment Patients
Duloxetine (Cymbalta) 6
Venlafaxine (Effexor XR) 6
Sertraline (Zoloft) 3
Citalopram (Celexa) 2
Escitalopram (Lexapro) 2

Show all 16 treatments patients report switching to

Last updated:

26 patient evaluations for Desvenlafaxine

228 members have decided to share their profiles only with other members of PatientsLikeMe.

dmwhite113@gmail.com
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dmwhite113@gmail.com
Gender: F
Data Quality: 1 star
Pain: Little
Fatigue: Little
Sleep: Little
Stiffness: Little
function: None
external_stress: None
Stickman: little
Description:F60y
FM:8y Dx
I am: n
I have:
Fibromyalgia

See dmwhite113@gmail.com's full Desvenlafaxine history

Jul 25, 2015 (Started Mar 15, 2014)

  • Effectiveness
    Can’t tell (for Major Depressive Disorder)
  • Side effects
    Moderate (Generalized Anxiety Disorder, Agoraphobia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I DID NOT REALLY REALIZE THE ANXIETY AND AGORAPHOBIA WAS BECAUSE OF THE PRISTIQ UNTIL RECENTLY.

  • 0 helpful marks
zoomer
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zoomer
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 1
Anxiety: 1
Compulsion: 0
External Stress: Moderate
61 F
Function: High
Distress: Low
I am: g
I have:
Bipolar I

See zoomer's full Desvenlafaxine history

Mar 15, 2015 (Started Mar 10, 2010)

  • Effectiveness
    Major (for Depressed mood)
  • Effectiveness
    Major (for Bipolar I Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

Apr 6, 2011 (Started Mar 10, 2010)

  • Effectiveness
    Major (for Bipolar I Disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: The efficacy for Bipolar1 is major because I am experiencing a significant decrease in the depressive episodes.(not having) Therefore, what a major wonder this anti depressant is doing so far. especially, because life circumstances kind of warrant depression..HA! and because I have had no side effects. I switched straight across from 120mg Cymbalta to the 100mg of Pristiq overnight. Last summer when starting Pristiq I attributed many side effects to the med. Maybe looking back, I was at a different place physiologically. I know we change and meds stop working or old ones do work that didn't work before. Hope you all find success..
Cost: < $25 monthly

  • 0 helpful marks
arachnoiditis555
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arachnoiditis555
Data Quality: 1 star
  • Gender: M
  • Age: 41
Condition: Arachnoiditis 3 additional condition(s)
Quality of life:
  • Mental: Moderate
  • Physical: Moderate
I am: n
I have:
Arachnoiditis

See arachnoiditis555's full Desvenlafaxine history

Jun 20, 2014 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Side effects
    Moderate (Sex drive (libido) decreased)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Advice & Tips: For me, this med worked pretty well for my depression, but it destroyed my libido. I have been off it for about a month, and my libido still isn't the same as it was before I started taking Pristiq. Not even close. I've tried other anti-depressants, and most did have a slight negative impact on my sex drive, however Pristiq has been devastating in that area. I'm wondering if the "old me" will ever return in respect to libido.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 26 patient evaluations for Desvenlafaxine