What is Desvenlafaxine?

Category: Prescription Drugs

Most popular types: Pristiq Exsira

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Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI). It is an extended release formulation believed to treat depression by affecting the levels of serotonin and norepinephrine, two neurotransmitters associated with depression.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 243 169
Major depressive disorder 202 138
Anxious mood 98 65
Fibromyalgia 41 32
Bipolar disorder 22 11
Pain 11 9

Show all 52 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 55
Moderate 68
Mild 88
None 151

Commonly reported side effects and conditions associated with Desvenlafaxine

Side effect Patients
Nausea 14
Sex drive (libido) decreased 11
Tiredness increased 11
Weight gain 11
Increased energy 9
Dizziness 8

Show all 126 reported side effects

Dosages

Based on patients currently taking Desvenlafaxine

Dosage Patients
50 mg daily 44
100 mg daily 37
25 mg daily 8
125 mg daily 1
150 mg daily 1
200 mg daily 1
625 mg daily 1
1,500 mg daily 1
3,000 mg daily 1
10,000 mg daily 1

Why patients stopped taking Desvenlafaxine

Multiple reasons could be selected

Reason Patients
Did not seem to work 84
Side effects too severe 62
Doctor's advice 43
Expense 41
Other 33
Change in health plan coverage 11
Personal research 7
Course of treatment ended 6
See all 203 patients who've stopped taking Desvenlafaxine

Duration

Currently taking Desvenlafaxine

Duration Patients
Less than 1 month 4
1 - 6 months 17
6 months - 1 year 10
1 - 2 years 17
2 - 5 years 17
5 - 10 years 28
10 years or more 3

Stopped taking Desvenlafaxine

Duration Patients
Less than 1 month 31
1 - 6 months 64
6 months - 1 year 43
1 - 2 years 35
2 - 5 years 24
5 - 10 years 7
Adherence
Adherence Evaluations
Always 309
Usually 37
Sometimes 4
Never taken as prescribed 12
Burden
Burden Evaluations
Very hard to take 14
Somewhat hard to take 26
A little hard to take 39
Not at all hard to take 283
Cost per month
Cost per month Evaluations
$200+ 7
$100-199 16
$50-99 39
$25-49 63
< $25 104
Not specified 133

What people switch to and from

Patients started taking Desvenlafaxine after stopping:

Treatment Patients
Venlafaxine (Effexor XR) 22
Fluoxetine (Prozac) 14
Duloxetine (Cymbalta) 12
Escitalopram (Lexapro) 11
Bupropion (Wellbutrin XL) 8

Show all 22 treatments patients report switching from

Patients stopped taking Desvenlafaxine and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 9
Fluoxetine (Prozac) 7
Duloxetine (Cymbalta) 6
Escitalopram (Lexapro) 3
Sertraline (Zoloft) 3

Show all 19 treatments patients report switching to

Last updated:

27 patient evaluations for Desvenlafaxine

Mar 22, 2017 (Started Jun 19, 2008)

  • Effectiveness
    Major (for Nerve pain (neuralgia))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Advice & Tips: 50 mg is for everyone but can go to 100 but usually no difference at all.. I was on effexor and then cynbalta both which didn't work out for me and then this one did.. all 3 are serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. ... It increases serotonin and norepinephrine activity in the brain, which regulates mood.
Cost: < $25 monthly

  • 0 helpful marks

Jul 25, 2015 (Started Mar 15, 2014)

  • Effectiveness
    Can’t tell (for major depressive disorder)
  • Side effects
    Moderate (agoraphobia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I DID NOT REALLY REALIZE THE ANXIETY AND AGORAPHOBIA WAS BECAUSE OF THE PRISTIQ UNTIL RECENTLY.

  • 0 helpful marks

Mar 15, 2015 (Started Mar 10, 2010)

  • Effectiveness
    Major (for Depressed mood)
  • Effectiveness
    Major (for bipolar I disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

Apr 6, 2011 (Started Mar 10, 2010)

  • Effectiveness
    Major (for bipolar I disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: The efficacy for Bipolar1 is major because I am experiencing a significant decrease in the depressive episodes.(not having) Therefore, what a major wonder this anti depressant is doing so far. especially, because life circumstances kind of warrant depression..HA! and because I have had no side effects. I switched straight across from 120mg Cymbalta to the 100mg of Pristiq overnight. Last summer when starting Pristiq I attributed many side effects to the med. Maybe looking back, I was at a different place physiologically. I know we change and meds stop working or old ones do work that didn't work before. Hope you all find success..
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 27 patient evaluations for Desvenlafaxine