What is Divalproex sodium?

Category: Prescription Drugs

Most popular types: Depakote Depakote ER Divalproex ER Show all

false

Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 579 271
Bipolar disorder 384 221
Migraine headaches 108 55
Bipolar II disorder 56 37
Bipolar I disorder 48 34
Bipolar manic episodes 45 34

Show all 117 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 182
Moderate 195
Mild 187
None 177

Commonly reported side effects and conditions associated with Divalproex sodium

Side effect Patients
Weight gain 144
Hair loss 45
Fatigue 40
Drowsiness 26
Tremor in hands 21
Nausea 18

Show all 222 reported side effects

Dosages

Based on patients currently taking Divalproex sodium

Dosage Patients
500 mg daily 18
1,000 mg daily 16
250 mg daily 15
500 mg twice daily 11
250 mg twice daily 9
750 mg daily 9
1,500 mg daily 8
2,000 mg daily 6
1,250 mg daily 5
500 mg three times daily 4

See all 28 dosages

Why patients stopped taking Divalproex sodium

Multiple reasons could be selected

Reason Patients
Side effects too severe 348
Did not seem to work 249
Doctor's advice 173
Other 106
Personal research 35
Expense 32
Course of treatment ended 26
Change in health plan coverage 11
See all 642 patients who've stopped taking Divalproex sodium

Duration

Currently taking Divalproex sodium

Duration Patients
Less than 1 month 1
1 - 6 months 4
6 months - 1 year 10
1 - 2 years 21
2 - 5 years 25
5 - 10 years 35
10 years or more 32

Stopped taking Divalproex sodium

Duration Patients
Less than 1 month 124
1 - 6 months 143
6 months - 1 year 74
1 - 2 years 78
2 - 5 years 125
5 - 10 years 52
10 years or more 56
Adherence
Adherence Evaluations
Always 582
Usually 115
Sometimes 22
Never taken as prescribed 22
Burden
Burden Evaluations
Very hard to take 56
Somewhat hard to take 117
A little hard to take 117
Not at all hard to take 451
Cost per month
Cost per month Evaluations
$200+ 19
$100-199 19
$50-99 33
$25-49 60
< $25 290
Not specified 320

What people switch to and from

Patients started taking Divalproex sodium after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 40
Lamotrigine (Lamictal) 20
Topiramate (Topamax) 16
Aripiprazole (Abilify) 10
Carbamazepine (Tegretol) 6

Show all 46 treatments patients report switching from

Patients stopped taking Divalproex sodium and switched to:

Treatment Patients
Lamotrigine (Lamictal) 32
Carbamazepine (Tegretol) 11
Levetiracetam (Keppra) 10
Lithium Carbonate (Lithium Carbonate ER) 10
Oxcarbazepine (Trileptal) 9

Show all 36 treatments patients report switching to

Last updated:

65 patient evaluations for Divalproex sodium

Sep 19, 2017 (Started Jun 30, 2012)

  • Effectiveness
    Slight (for bipolar disorder)
  • Side effects
    Moderate (head pressure)
  • Adherence
    Sometimes
  • Burden
    Somewhat hard to take
Dosage: 500 mg Daily
Cost: < $25 monthly

Apr 9, 2016 (Started Jun 30, 2012)

  • Effectiveness
    Slight (for bipolar disorder)
  • Side effects
    Mild (head pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 250 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 250 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 250 mg All the time (24/7)

  • 0 helpful marks

Sep 23, 2016 (Started Feb 28, 2015)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 65 patient evaluations for Divalproex sodium