What is Zoledronic acid?

Category: Prescription Drugs

Most popular types: Zometa Reclast

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Zoledronic acid is a bisphosphonate used in the treatment of hypercalcemia of malignancy (albumin-corrected serum calcium ≥12 mg/dL), multiple myeloma, bone metastases of solid tumors, Paget's disease of bone, postmenopausal osteoporosis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Osteoporosis 47 30
Multiple myeloma 29 14
Osteopenia 12 8
Bone metastases 3 1
Bone pain 2 1
Arthritis pain in spine 1 0

Show all 14 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 5
Moderate 5
Mild 4
None 31

Commonly reported side effects and conditions associated with Zoledronic acid

Side effect Patients
Flu like symptoms 4
Fever/chills 3
Bone pain 2
Abdominal cramps 1
Allergic reaction 1
Broken leg (right) 1

Show all 20 reported side effects

Dosages

Based on patients currently taking Zoledronic acid

Dosage Patients
0.04 mg monthly 5
5 mg/100 mL yearly 4
4 mg/5 mL every 3 months 4
50 mcg yearly 4
4 mg/5ml monthly 3
4 mg every 3 months 2
0.04 mg yearly 1
0.04 mg every 3 months 1
1 intl units yearly 1
0.04 mg weekly 1

See all 17 dosages

Why patients stopped taking Zoledronic acid

Multiple reasons could be selected

Reason Patients
Doctor's advice 12
Side effects too severe 6
Course of treatment ended 5
Other 2
Change in health plan coverage 1
Did not seem to work 1
Expense 1
See all 20 patients who've stopped taking Zoledronic acid

Duration

Currently taking Zoledronic acid

Duration Patients
1 - 6 months 4
6 months - 1 year 5
1 - 2 years 7
2 - 5 years 8
5 - 10 years 10

Stopped taking Zoledronic acid

Duration Patients
Less than 1 month 3
1 - 6 months 2
6 months - 1 year 1
1 - 2 years 8
2 - 5 years 4
5 - 10 years 1
10 years or more 1
Adherence
Adherence Evaluations
Always 40
Usually 1
Sometimes 0
Never taken as prescribed 4
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 7
A little hard to take 7
Not at all hard to take 31
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 2
$50-99 2
$25-49 4
< $25 10
Not specified 27

What people switch to and from

Patients started taking Zoledronic acid after stopping:

Treatment Patients
Alendronate (Fosamax) 2
Pamidronate (Aredia) 2

Patients stopped taking Zoledronic acid and switched to:

Treatment Patients
Pamidronate (Aredia) 2
Denosumab (Prolia) 1
Raloxifene (Evista) 1
Last updated:

5 patient evaluations for Zoledronic acid

Dec 28, 2016 (Started Apr 23, 2009)

  • Effectiveness
    Major (for osteoporosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg/100 mL Yearly
Advice & Tips: IT REALLY WORKS!!

Aug 11, 2015 (Started Apr 23, 2009)

  • Effectiveness
    Major (for osteoporosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg/100 mL Yearly
Advice & Tips: THERE HAS BEEN SIGNIFICANT IMPROVEMENT IN MY OSTEOPOROSIS WHICH IS GREAT

Jun 29, 2014 (Started Apr 23, 2009)

  • Effectiveness
    Major (for osteoporosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg/100 mL Yearly

Jul 14, 2012 (Started Apr 23, 2009)

  • Effectiveness
    Major (for osteoporosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg/100 mL Yearly
Advice & Tips: I WAS TOLD IT MADE A SIGNIFICANT IMPROVEMENT IN MY OSTEOPOROSIS.

  • 1 helpful mark

Feb 15, 2015 (Started Nov 01, 2009)

  • Effectiveness
    Major (for osteoporosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 5 mg/100 mL Yearly
Advice & Tips: Doctor said to stop this treatment after using for 3 or 4 years, as new research shows potential for problems developing over time.  Switched to Evista with testing in 2 years from start of Evista. 

  • 0 helpful marks

Nov 18, 2013 (Started Oct 25, 2011)

  • Effectiveness
    Moderate (for osteoporosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take

  • 1 helpful mark
Last updated:
Showing 3 of 5 patient evaluations for Zoledronic acid