What is Zoledronic acid?

Category: Prescription Drugs

Most popular types: Reclast Zometa

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Zoledronic acid is a bisphosphonate used in the treatment of hypercalcemia of malignancy (albumin-corrected serum calcium ≥12 mg/dL), multiple myeloma, bone metastases of solid tumors, Paget's disease of bone, postmenopausal osteoporosis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Osteoporosis 42 22
Multiple Myeloma 17 10
Osteopenia 10 6
Bone Metastases 2 1
Arthritis pain in spine 1 0
Bone loss 1 0

Show all 12 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 4
Moderate 4
Mild 4
None 22

Commonly reported side effects and conditions associated with Zoledronic acid

Side effect Patients
Fever/chills 3
Flu like symptoms 3
Bone Pain 2
Dehydration 2
Abdominal cramps 1
Deep aches 1

Show all 20 reported side effects

Dosages

Based on patients currently taking Zoledronic acid

Dosage Patients
5 mg/100 mL yearly 4
4 mg/5 mL every 3 months 2
0.04 mg yearly 1
0.8 mg monthly 1
3.3 mg every 3 months 1
4 mg every 3 months 1
50 mcg yearly 1
90 mg every 3 months 1
0.05 mg every 6 months 1
4 mg/5 mL every 6 months 1

Why patients stopped taking Zoledronic acid

Multiple reasons could be selected

Reason Patients
Doctor's advice 9
Course of treatment ended 5
Side effects too severe 5
Other 2
Change in health plan coverage 1
Did not seem to work 1
Expense 1
See all 17 patients who’ve stopped taking Zoledronic acid

Duration

Currently taking Zoledronic acid

Duration Patients
1 - 6 months 2
6 months - 1 year 2
1 - 2 years 1
2 - 5 years 4
5 - 10 years 5
10 years or more 1

Stopped taking Zoledronic acid

Duration Patients
Less than 1 month 3
1 - 6 months 1
6 months - 1 year 1
1 - 2 years 8
2 - 5 years 3
5 - 10 years 1
Adherence
Adherence Evaluations
Always 31
Usually 1
Sometimes 0
Never taken as prescribed 2
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 6
A little hard to take 5
Not at all hard to take 23
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 2
$50-99 2
$25-49 4
< $25 7
Not specified 19

What people switch to and from

Patients started taking Zoledronic acid after stopping:

Treatment Patients
Pamidronate (Aredia) 2
Alendronate (Fosamax) 1

Patients stopped taking Zoledronic acid and switched to:

Treatment Patients
Pamidronate (Aredia) 2
Denosumab (Prolia) 1
Raloxifene (Evista) 1
Last updated:

5 patient evaluations for Zoledronic acid

23 members have decided to share their profiles only with other members of PatientsLikeMe.

rose5
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rose5
Sex: F
Data Quality: 2 stars
On
Mouth/throat: moderate
Arms: moderate
Chest: severe
Legs: severe
I am: vb
I have:
Parkinson's

See rose5's full Zoledronic acid history

Aug 11, 2015 (Started Apr 23, 2009)

  • Effectiveness
    Major (for Osteoporosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg/100 mL Yearly
Advice & Tips: THERE HAS BEEN SIGNIFICANT IMPROVEMENT IN MY OSTEOPOROSIS WHICH IS GREAT

Jun 29, 2014 (Started Apr 23, 2009)

  • Effectiveness
    Major (for Osteoporosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg/100 mL Yearly

Jul 14, 2012 (Started Apr 23, 2009)

  • Effectiveness
    Major (for Osteoporosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg/100 mL Yearly
Advice & Tips: I WAS TOLD IT MADE A SIGNIFICANT IMPROVEMENT IN MY OSTEOPOROSIS.

  • 1 helpful mark
rainydaygirl
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rainydaygirl
Gender: F
Data Quality: 2 stars
Pain: Some
Fatigue: All
Sleep: All
Stiffness: Most
function: None
external_stress: Little
Stickman: most
Description:F73y
FM:27y Dx
CFS:8y Dx
I am: vb
I have:
Fibromyalgia

See rainydaygirl's full Zoledronic acid history

Feb 15, 2015 (Started Nov 01, 2009)

  • Effectiveness
    Major (for Osteoporosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 5 mg/100 mL Yearly
Advice & Tips: Doctor said to stop this treatment after using for 3 or 4 years, as new research shows potential for problems developing over time.  Switched to Evista with testing in 2 years from start of Evista. 

  • 0 helpful marks
samantha12
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samantha12
Gender: M
Data Quality: 2 stars
Mental Symptoms : moderate
Physical Symptoms : mild
745
VL 0
I am: n
I have:
HIV

See samantha12's full Zoledronic acid history

Nov 18, 2013 (Started Oct 25, 2011)

  • Effectiveness
    Moderate (for Osteoporosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take

  • 1 helpful mark
Last updated:
Showing 3 of 5 patient evaluations for Zoledronic acid