What is Sertraline?

Category: Prescription Drugs

Most popular types: Zoloft Apo-Sertraline Lustral Show all

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Sertraline, a selective serotonin reuptake inhibitor (SSRI) antidepressant, is used in the treatment of major depression, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and social anxiety disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 1,743 854
major depressive disorder 1,494 805
post-traumatic stress disorder 672 397
Anxious mood 483 210
panic disorder 305 186
persistent depressive disorder (dysthymia) 207 150

Show all 210 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 236
Moderate 427
Mild 493
None 771

Commonly reported side effects and conditions associated with Sertraline

Side effect Patients
Weight gain 120
Dry mouth 79
Sex drive (libido) decreased 78
Fatigue 67
Loss of sex drive (libido) 67
Nausea 44

Show all 378 reported side effects

Dosages

Based on patients currently taking Sertraline

Dosage Patients
100 mg daily 197
50 mg daily 159
200 mg daily 94
150 mg daily 90
25 mg daily 58
100 mg twice daily 25
75 mg daily 12
50 mg twice daily 12
200 mg twice daily 6
20 mg daily 4

See all 39 dosages

Why patients stopped taking Sertraline

Multiple reasons could be selected

Reason Patients
Did not seem to work 701
Side effects too severe 462
Doctor's advice 401
Other 270
Course of treatment ended 87
Personal research 80
Expense 59
Change in health plan coverage 45
See all 1475 patients who've stopped taking Sertraline

Duration

Currently taking Sertraline

Duration Patients
Less than 1 month 4
1 - 6 months 66
6 months - 1 year 96
1 - 2 years 95
2 - 5 years 167
5 - 10 years 137
10 years or more 132

Stopped taking Sertraline

Duration Patients
Less than 1 month 242
1 - 6 months 313
6 months - 1 year 239
1 - 2 years 221
2 - 5 years 254
5 - 10 years 134
10 years or more 83
Adherence
Adherence Evaluations
Always 1507
Usually 280
Sometimes 68
Never taken as prescribed 72
Burden
Burden Evaluations
Very hard to take 79
Somewhat hard to take 131
A little hard to take 291
Not at all hard to take 1426
Cost per month
Cost per month Evaluations
$200+ 8
$100-199 20
$50-99 19
$25-49 75
< $25 976
Not specified 829

What people switch to and from

Patients started taking Sertraline after stopping:

Treatment Patients
Fluoxetine (Prozac) 82
Citalopram (Celexa) 66
Bupropion (Wellbutrin XL) 45
Venlafaxine (Effexor XR) 35
Duloxetine (Cymbalta) 31

Show all 52 treatments patients report switching from

Patients stopped taking Sertraline and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 60
Duloxetine (Cymbalta) 51
Bupropion (Wellbutrin XL) 50
Fluoxetine (Prozac) 42
Escitalopram (Lexapro) 38

Show all 42 treatments patients report switching to

Last updated:

146 patient evaluations for Sertraline

MSMomx4
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MSMomx4
Sex: F
Data Quality: 2 stars
Sensation: Mild
Overall: Mild
Cognition: moderate
Vision: mild
Speech: mild
Swallowing: mild
Upper limb: mild
Walking: moderate
I am: g
I have:
MS

See MSMomx4's full Sertraline history

Feb 15, 2017 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: No changes
Cost: < $25 monthly

Nov 30, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: No changes since 3/20/15
Cost: < $25 monthly

Aug 2, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

May 9, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Apr 24, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 1, 2016 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Moderate (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Oct 21, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Mar 20, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: My digestive problems have been resolved. I have no other conditions that would lead a doctor to think I had anything seriously wrong with me. I now take 150 mgs of Zoloft. I take it every day with no problem.
Cost: < $25 monthly

Feb 4, 2015 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: The only problem I've had is bad diarhea, from starting to take it again after not having been on it for about a month. This was due to a change in providers.
Cost: < $25 monthly

Oct 28, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Sep 10, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: I am now taking 200 mg a day (4 50mg tabs a day). I have no problems with taking it at all.
Cost: < $25 monthly

Jun 2, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Mild (Sleep problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

May 8, 2014 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Jan 17, 2011 (Started Jul 07, 1996)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: it has had no impact on my lifestyle at all. It is a pill taken once a day.
Cost: < $25 monthly

  • 0 helpful marks
leejon66
67203 thumb
leejon66
Gender: M
Data Quality: 2 stars
Depression: 0
Mania: 0
Emotional: 1
Anxiety: 3
Compulsion: 2
External Stress: Low
68 M
Function: High
Distress: Low
I am: b
I have:
PTSD

See leejon66's full Sertraline history

Feb 12, 2017 (Started Jul 01, 1982)

  • Effectiveness
    None (for post-traumatic stress disorder)
  • Effectiveness
    None (for panic disorder)
  • Effectiveness
    None (for major depressive disorder)
  • Effectiveness
    None (for Depressed mood)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Somewhat hard to take
Dosage: Yearly
Cost: < $25 monthly

  • 0 helpful marks
mrsnurse
53908 thumb
mrsnurse
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: None
Cognition: moderate
Vision: none
Speech: none
Swallowing: none
Upper limb: moderate
Walking: none
I am: g
I have:
MS

See mrsnurse's full Sertraline history

Feb 12, 2017 (Started Aug 14, 1993)

  • Effectiveness
    Moderate (for Emotional lability)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: I always take this treatment because MS can actually cause depresion, and since the MS has caused me to lose so much in my life, I know without a doubt I must take this!!

  • 0 helpful marks
Last updated:
Showing 3 of 146 patient evaluations for Sertraline