What is Glatiramer acetate?

Category: Prescription Drugs

Most popular types: Copaxone Glatopa

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Glatiramer acetate combines four amino acids including L-alanine, L-glutamic acid, L-lysine and L-tyrosine. It is used for Relapsing-Remitting Multiple Sclerosis (RRMS) to reduce the frequency and severity of relapses. It is administered as a subcutaneous injection.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 5,525 2,926
General health 69 48
Stiffness/spasticity 47 18
Fatigue 27 18
Pain 10 2

Show all 46 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
285
Moderate
488
Mild
1,353
None
840

Commonly reported side effects and conditions associated with Glatiramer acetate

Side effect Patients
Injection site reaction 392
Injection site pain 328
Injection site itching 279
Lumps and bumps 265
Redness 221
Bruising 153

Show all 394 reported side effects

Dosages

Based on patients currently taking Glatiramer acetate

Dosage Patients
20 mg daily 205
40 mg m,w,f 72
40 mg 3 times a week 70
daily 13
40 mg every other day 12
20 mg every other day 10
20 mg 3 times a week 7
40 mg three times daily 6
120 mg weekly 4
20 mg weekly 3

See all 29 dosages

Why patients stopped taking Glatiramer acetate

Multiple reasons could be selected

Reason Patients
Did not seem to work 971
Side effects too severe 765
Doctor's advice 733
Other 529
Expense 158
Personal research 136
Change in health plan coverage 81
Course of treatment ended 43
See all 2390 patients who've stopped taking Glatiramer acetate

Duration

Currently taking Glatiramer acetate

Duration Patients
1 - 6 months 17
6 months - 1 year 24
1 - 2 years 40
2 - 5 years 77
5 - 10 years 147
10 years or more 125

Stopped taking Glatiramer acetate

Duration Patients
Less than 1 month 191
1 - 6 months 409
6 months - 1 year 413
1 - 2 years 421
2 - 5 years 585
5 - 10 years 298
10 years or more 88
Adherence
Adherence Evaluations
Always 2169
Usually 576
Sometimes 99
Never taken as prescribed 122
Burden
Burden Evaluations
Very hard to take 260
Somewhat hard to take 662
A little hard to take 993
Not at all hard to take 1051
Cost per month
Cost per month Evaluations
$200+ 241
$100-199 102
$50-99 201
$25-49 486
< $25 1137
Not specified 799

What people switch to and from

Patients started taking Glatiramer acetate after stopping:

Treatment Patients
Interferon beta-1a IM Injection (Avonex) 63
Interferon beta-1a SubQ injection (Rebif) 51
Dimethyl fumarate (Tecfidera) 38
Interferon beta-1b SubQ Injection (Betaseron) 26
Natalizumab (Tysabri) 15

Show all 13 treatments patients report switching from

Patients stopped taking Glatiramer acetate and switched to:

Treatment Patients
Dimethyl fumarate (Tecfidera) 95
Natalizumab (Tysabri) 61
Fingolimod (Gilenya) 39
Teriflunomide (Aubagio) 39
Interferon beta-1a SubQ injection (Rebif) 34

Show all 25 treatments patients report switching to

Last updated:

252 patient evaluations for Glatiramer acetate

Dec 15, 2017 (Started Jun 09, 2016)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    Mild (injection site lumps and bumps)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 40 mg 3 times a week
Advice & Tips: I feel like I have more energy since starting the Copaxone injections. Since going on Medicare with a Part D supplement, my out- of-pocket has gone from $0 to an average of $500/month.
Cost: $200+ monthly

Dec 12, 2016 (Started Jun 09, 2016)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    Mild (injection site lumps and bumps)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 40 mg 3 times a week
Advice & Tips: I'm not sure yet how effective Copaxone is in reducing exacerbations, I've only taken it for 6 months.  But an unexpected positive is that I have noticed my energy level has improved - even early on in the summer (when I usually slow down a lot due to the heat), I felt an increased energy.  
Cost: < $25 monthly

  • 0 helpful marks

Sep 16, 2017 (Started Sep 15, 2015)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    Mild (injection site bruising)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 40 mg M,W,F
Cost: < $25 monthly

Aug 25, 2013 (Started Sep 15, 2015)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Mild (injection site bruising)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: There are less injection site reactions when one very carefully rotates injection sites. I track locations every night in a journal provided by Shared Solutions. I do my injections every night just before going to bed.
Cost: < $25 monthly

  • 0 helpful marks

Aug 18, 2017 (Started Aug 08, 2002)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Moderate (injection site itching, lumps and bumps, redness, injection site reaction, itching)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 40 mg 3 times a week
Advice & Tips: My initial injection from two days ago is still a welt and itchy (on my abdomen). Gave my new shot in the arm using the Autoject and preceded by a hot compress. That seems to have made a nice difference with itching and welt. Will have to see how things look the day after. The autoject was actually better than I thought. I used a depth of "4" and it seemed to really work.
Cost: < $25 monthly
Side effects: injection site itching, injection site reaction, redness, itching, lumps and bumps

Aug 16, 2017 (Started Aug 08, 2002)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Mild (injection site itching, lumps and bumps, redness, injection site reaction, itching)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 40 mg 3 times a week
Advice & Tips: I have started the Copaxone 40mgs 3X a week injection and this will be a lifesaver for me. I also used some Benadryl cream after the injection and this helped with the site injection welt I typically get. Remarkable results using that cream. Wish I would have known earlier! I have to go on a DMD after my last relapse. Don't want any more issues.
Cost: < $25 monthly
Side effects: injection site itching, injection site reaction, redness, itching, lumps and bumps

Aug 15, 2017 (Started Aug 08, 2002)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Severe (injection site itching, lumps and bumps, redness, injection site reaction, itching)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Advice & Tips: I have discontinued Copaxone 40 mgs after a bad allergic reaction (anaphylactic reaction whcih was more than the immediate post injection reaction). Face flushing, chest and back pain, throat closing, extreme chest and back pain and heart rate jumping around from 55 to 155 in a matter of a minute - feeling of doom, thought I was dying for sure but did everything to stay calm and took 50 mgs of Benadryl and Combivent. It was pretty horrible to be honest. I have started Aubagio and am on my second dose today. Some diarrhea and night sweats.
Cost: < $25 monthly
Side effects: injection site itching, injection site reaction, redness, itching, lumps and bumps

Oct 5, 2014 (Started Aug 08, 2002)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Severe (injection site itching, lumps and bumps, redness, injection site reaction, itching)
  • Adherence
    Usually
  • Burden
    Very hard to take
Dosage: 20 mg Daily
Advice & Tips: This round of Copaxone has not been good for me. I have now developed large, itchy welts that are still present over 5 days later with no sign of going away. I am concerned about cellulitis and my risk for that. This drug is not worth the hassle for me.
Cost: < $25 monthly
Side effects: injection site itching, injection site reaction, redness, itching, lumps and bumps

Oct 3, 2014 (Started Aug 08, 2002)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Moderate (lumps and bumps, redness, injection site reaction, itching)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 20 mg Daily
Advice & Tips: I have started Copaxone again and am now getting large, itchy welts (like a large mosquito bite that have lasted almost 48 hours). Feels more like an allergic reaction of some type????
Cost: < $25 monthly
Side effects: injection site itching, injection site reaction, redness, itching, lumps and bumps

May 17, 2011 (Started Aug 08, 2002)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Mild (lumps and bumps, redness, injection site reaction, itching)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 20 mg Daily
Advice & Tips: I am stopping it as a test since I am relatively stable at this point and the doctor wants to really evaluate my MS versus Fibromylagia.
Cost: < $25 monthly
Side effects: injection site itching, injection site reaction, redness, itching, lumps and bumps

Sep 19, 2010 (Started Aug 08, 2002)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 20 mg Daily
Advice & Tips: The shot is going to sting a little bit. To cut down on the sting, make sure that the drop on the end of the needle is shaken away and make sure the alcohol on the site is dried.
Cost: < $25 monthly
Side effects: injection site itching, injection site reaction, redness, itching, lumps and bumps

May 11, 2010 (Started Aug 08, 2002)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (lumps and bumps, redness, injection site reaction, itching)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: Very easy to take.
Cost: < $25 monthly
Side effects: injection site itching, injection site reaction, redness, itching, lumps and bumps

Mar 4, 2009 (Started Aug 08, 2002)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (lumps and bumps, redness, injection site reaction)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: I would choose a Copaxone daily injection even over an oral therapy that acted with the side-effects of an Interferon. I don't mind the needle at all.
Cost: < $25 monthly
Side effects: injection site itching, injection site reaction, redness, itching, lumps and bumps

  • 0 helpful marks
Last updated:
Showing 3 of 252 patient evaluations for Glatiramer acetate