What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,312 1,302
Depressed mood 1,618 805
Persistent depressive disorder (dysthymia) 405 331
Mild depression 155 69
Anxious mood 121 67
Bipolar disorder 112 94

Show all 192 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 275
Moderate 379
Mild 620
None 1,144

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 108
Anxious mood 70
Weight gain 58
Insomnia 53
Headaches 48
Constipation 42

Show all 442 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 179
150 mg daily 142
300 mg/24 hours daily 64
100 mg daily 61
450 mg daily 50
75 mg daily 44
150 mg twice daily 38
100 mg twice daily 29
150 mg/24 hours daily 27
200 mg daily 24

See all 58 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 662
Side effects too severe 557
Doctor's advice 433
Other 279
Course of treatment ended 93
Expense 85
Personal research 73
Change in health plan coverage 44
See all 1620 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 4
1 - 6 months 36
6 months - 1 year 80
1 - 2 years 114
2 - 5 years 206
5 - 10 years 187
10 years or more 163

Stopped taking Bupropion

Duration Patients
Less than 1 month 358
1 - 6 months 358
6 months - 1 year 235
1 - 2 years 230
2 - 5 years 286
5 - 10 years 128
10 years or more 64
Adherence
Adherence Evaluations
Always 1898
Usually 356
Sometimes 51
Never taken as prescribed 113
Burden
Burden Evaluations
Very hard to take 83
Somewhat hard to take 146
A little hard to take 341
Not at all hard to take 1848
Cost per month
Cost per month Evaluations
$200+ 15
$100-199 25
$50-99 86
$25-49 175
< $25 1163
Not specified 954

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 96
Fluoxetine (Prozac) 91
Venlafaxine (Effexor XR) 74
Citalopram (Celexa) 54
Duloxetine (Cymbalta) 49

Show all 56 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 52
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 33
Fluoxetine (Prozac) 31

Show all 49 treatments patients report switching to

Last updated:

188 patient evaluations for Bupropion

Apr 11, 2018 (Started May 15, 2017)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Cost: $200+ monthly

  • 0 helpful marks

Jan 12, 2018 (Started Jun 30, 2017)

  • Effectiveness
    Moderate (for chronic fatigue)
  • Side effects
    Severe (vomiting, nausea)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 100 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks

Dec 15, 2017 (Started Jun 01, 2006)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Severe (insomnia, hot flashes, feeling tense or on edge, feeling feverish, facial flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Advice & Tips: If you are taking the generic extended release make sure it is not dose dumping - releasing too much medicine at once causing side effects. My MS doctor, PCP, and I thought I was in menopause with all the hot flashes and fevers of 99.6! Even kept going in to see if I had a UTI bc of the fevers! What a waste of my time and money!!!
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 188 patient evaluations for Bupropion