What is Desvenlafaxine?

Category: Prescription Drugs

Most popular types: Pristiq Exsira

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Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI). It is an extended release formulation believed to treat depression by affecting the levels of serotonin and norepinephrine, two neurotransmitters associated with depression.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 253 182
Major depressive disorder 222 152
Anxious mood 107 79
Fibromyalgia 41 35
Bipolar disorder 24 12
Pain 12 10

Show all 51 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 55
Moderate 69
Mild 93
None 165

Commonly reported side effects and conditions associated with Desvenlafaxine

Side effect Patients
Decreased sex drive (libido) 16
Weight gain 13
Nausea 12
Dizziness 8
Dry mouth 8
Sedation 8

Show all 101 reported side effects

Dosages

Based on patients currently taking Desvenlafaxine

Dosage Patients
50 mg daily 32
100 mg daily 31
150 mg daily 5
25 mg daily 4
200 mg daily 3
625 mg daily 1
10,000 mg daily 1
10,000 mg twice daily 1

Why patients stopped taking Desvenlafaxine

Multiple reasons could be selected

Reason Patients
Did not seem to work 91
Side effects too severe 61
Doctor's advice 45
Expense 42
Other 32
Change in health plan coverage 11
Personal research 7
Course of treatment ended 6
See all 209 patients who've stopped taking Desvenlafaxine

Duration

Currently taking Desvenlafaxine

Duration Patients
1 - 6 months 3
6 months - 1 year 5
1 - 2 years 17
2 - 5 years 21
5 - 10 years 26
10 years or more 6

Stopped taking Desvenlafaxine

Duration Patients
Less than 1 month 33
1 - 6 months 65
6 months - 1 year 42
1 - 2 years 37
2 - 5 years 26
5 - 10 years 7
Adherence
Adherence Evaluations
Always 328
Usually 38
Sometimes 3
Never taken as prescribed 13
Burden
Burden Evaluations
Very hard to take 14
Somewhat hard to take 27
A little hard to take 44
Not at all hard to take 297
Cost per month
Cost per month Evaluations
$200+ 7
$100-199 15
$50-99 38
$25-49 69
< $25 113
Not specified 140

What people switch to and from

Patients started taking Desvenlafaxine after stopping:

Treatment Patients
Venlafaxine (Effexor XR) 26
Duloxetine (Cymbalta) 15
Fluoxetine (Prozac) 13
Bupropion (Wellbutrin XL) 12
Escitalopram (Lexapro) 12

Show all 27 treatments patients report switching from

Patients stopped taking Desvenlafaxine and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 9
Duloxetine (Cymbalta) 6
Fluoxetine (Prozac) 5
Escitalopram (Lexapro) 3
Sertraline (Zoloft) 3

Show all 21 treatments patients report switching to

Last updated:

27 patient evaluations for Desvenlafaxine

Jun 8, 2018 (Started Dec 19, 2017)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Advice & Tips: Now taking 200mg pill. It is the target dosage. It seems to be working fine.
Cost: $25-49 monthly

Jan 23, 2018 (Started Dec 19, 2017)

  • Effectiveness
    Can't tell (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Advice & Tips: Takes a while to work. hoping for the best.
Cost: $25-49 monthly

Dec 27, 2017 (Started Dec 19, 2017)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 25 mg Daily
Advice & Tips: It takes awhile to start to work. My Dr. set me up on 25mg but I feel I should be on a stronger dosage. Will take that up with her at my next appointment.
Cost: $25-49 monthly

  • 0 helpful marks

Mar 22, 2017 (Started Jun 19, 2008)

  • Effectiveness
    Major (for nerve pain (neuralgia))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Advice & Tips: 50 mg is for everyone but can go to 100 but usually no difference at all.. I was on effexor and then cynbalta both which didn't work out for me and then this one did.. all 3 are serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. ... It increases serotonin and norepinephrine activity in the brain, which regulates mood.
Cost: < $25 monthly

  • 0 helpful marks

Jul 25, 2015 (Started Mar 15, 2014)

  • Effectiveness
    Can't tell (for major depressive disorder)
  • Side effects
    Moderate (agoraphobia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Advice & Tips: I DID NOT REALLY REALIZE THE ANXIETY AND AGORAPHOBIA WAS BECAUSE OF THE PRISTIQ UNTIL RECENTLY.

  • 0 helpful marks
Last updated:
Showing 3 of 27 patient evaluations for Desvenlafaxine