What is Fludrocortisone?

Category: Prescription Drugs

Most popular types: Florinef

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Fludrocortisone is a synthetic corticosteroid. It is used primarily to replace the missing hormone aldosterone in various forms of adrenal insufficiency such as Addison's disease and congenital adrenal hyperplasia. It is the first line of treatment for orthostatic intolerance.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Postural orthostatic tachycardia syndrome 76 41
Addison's disease 32 16
Orthostatic hypotension 32 23
Orthostatic postural hypotension 28 15
Multiple system atrophy 25 12

Show all 51 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 13
Moderate 20
Mild 19
None 54

Commonly reported side effects and conditions associated with Fludrocortisone

Side effect Patients
Weight gain 10
Headaches 5
Dry mouth 2
Fatigue 2
Migraine headaches 2
Nausea 2

Show all 27 reported side effects

Dosages

Based on patients currently taking Fludrocortisone

Dosage Patients
0.1 mg daily 13
0.1 mg twice daily 5
0.2 mg daily 4
0.05 mg daily 3
0.15 mg daily 2
0.5 mg daily 2
0.01 mg twice daily 1
0.01 mg three times daily 1
0.1 mg every other day 1
0.05 mg twice daily 1

See all 14 dosages

Why patients stopped taking Fludrocortisone

Multiple reasons could be selected

Reason Patients
Side effects too severe 23
Did not seem to work 18
Doctor's advice 15
Other 7
Course of treatment ended 5
Personal research 4
See all 57 patients who've stopped taking Fludrocortisone

Duration

Currently taking Fludrocortisone

Duration Patients
6 months - 1 year 2
1 - 2 years 3
2 - 5 years 14
5 - 10 years 10
10 years or more 8

Stopped taking Fludrocortisone

Duration Patients
Less than 1 month 15
1 - 6 months 17
6 months - 1 year 8
1 - 2 years 9
2 - 5 years 6
5 - 10 years 4
Adherence
Adherence Evaluations
Always 87
Usually 15
Sometimes 0
Never taken as prescribed 4
Burden
Burden Evaluations
Very hard to take 3
Somewhat hard to take 6
A little hard to take 12
Not at all hard to take 85
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 1
$50-99 0
$25-49 4
< $25 45
Not specified 55

What people switch to and from

Patients started taking Fludrocortisone after stopping:

Treatment Patients
Midodrine (ProAmatine) 6
Prednisone (Deltasone) 2
Pyridostigmine (Mestinon) 1

Patients stopped taking Fludrocortisone and switched to:

Treatment Patients
Midodrine (ProAmatine) 3
Droxidopa (Northera) 1
Hydrocortisone (Cortef) 1
Irbesartan (Avapro) 1
Prednisone (Deltasone) 1

Show all 6 treatments patients report switching to

Last updated:

7 patient evaluations for Fludrocortisone

Jul 7, 2016 (Started Dec 15, 2009)

  • Effectiveness
    Moderate (for orthostatic postural hypotension)
  • Effectiveness
    Moderate (for multiple system atrophy)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 0.1 mg Daily
Advice & Tips: I am no longer taking this medication. I am now on Northera.

  • 0 helpful marks

May 18, 2015 (Started Jul 01, 2014)

  • Effectiveness
    Slight (for vasovagal syncope)
  • Side effects
    Mild (feeling of heart pounding)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.2 mg Daily

  • 0 helpful marks

Dec 23, 2014 (Started Nov 15, 2014)

  • Effectiveness
    Slight (for Addison's disease)
  • Side effects
    Severe (chronic headaches)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.1 mg Daily
Advice & Tips: I've been having horrible, debilitating headaches. I only realized it may be a side effect of this medication after taking it for several weeks. I'm going to call my doctor today. And I'm not going to take it. So, I would advise others to be aware of any changes in their symptoms.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 7 patient evaluations for Fludrocortisone