What is Mesalamine?

Category: Prescription Drugs

Most popular types: Pentasa Asacol Lialda Show all

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Mesalamine, a derivative of 5-aminosalicylic acid, is an anti-inflammatory agent. It can be used to treat ulcerative colitis and Crohn’s disease. It can be taken orally or applied rectally to help treat the inflammation associated with these conditions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Crohn's disease 254 100
Ulcerative colitis 190 99
Diarrhea 6 6
Microscopic colitis 6 4
Chronic diarrhea 3 2

Show all 22 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
11
Moderate
25
Mild
32
None
146

Commonly reported side effects and conditions associated with Mesalamine

Side effect Patients
Diarrhea 7
Headaches 6
Nausea 6
Hair loss 5
Fatigue 4
Abdominal bloating 2

Show all 73 reported side effects

Dosages

Based on patients currently taking Mesalamine

Dosage Patients
2.4 g daily 4
400 mg daily 3
1,000 mg four times daily 3
1.5 g daily 2
1,500 mg daily 2
2,400 mg daily 2
2 x 1,200 mg daily 2
800 mg three times daily 2
1,000 mg three times daily 2
1,600 mg twice daily 2

See all 33 dosages

Why patients stopped taking Mesalamine

Multiple reasons could be selected

Reason Patients
Did not seem to work 97
Doctor's advice 59
Side effects too severe 35
Other 28
Expense 16
Course of treatment ended 15
Change in health plan coverage 8
Personal research 8
See all 174 patients who've stopped taking Mesalamine

Duration

Currently taking Mesalamine

Duration Patients
1 - 6 months 2
6 months - 1 year 1
1 - 2 years 8
2 - 5 years 20
5 - 10 years 6
10 years or more 11

Stopped taking Mesalamine

Duration Patients
Less than 1 month 36
1 - 6 months 46
6 months - 1 year 21
1 - 2 years 26
2 - 5 years 20
5 - 10 years 18
10 years or more 17
Adherence
Adherence Evaluations
Always 157
Usually 41
Sometimes 7
Never taken as prescribed 9
Burden
Burden Evaluations
Very hard to take 14
Somewhat hard to take 32
A little hard to take 51
Not at all hard to take 117
Cost per month
Cost per month Evaluations
$200+ 12
$100-199 9
$50-99 9
$25-49 25
< $25 54
Not specified 105

What people switch to and from

Patients started taking Mesalamine after stopping:

Treatment Patients
Sulfasalazine (Salazopyrin) 12
Mesalamine (Pentasa) 6
Balsalazide (Colazal) 3
Infliximab (Remicade) 2
Mercaptopurine (Purinethol) 2

Show all 8 treatments patients report switching from

Patients stopped taking Mesalamine and switched to:

Treatment Patients
Infliximab (Remicade) 8
Mesalamine (Pentasa) 6
Sulfasalazine (Salazopyrin) 6
Adalimumab (Humira) 4
Balsalazide (Colazal) 3

Show all 10 treatments patients report switching to

Last updated:

11 patient evaluations for Mesalamine

Jul 11, 2015 (Started Jan 15, 2014)

  • Effectiveness
    Moderate (for Crohn's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2.4 g Daily
Cost: $50-99 monthly

  • 0 helpful marks

May 31, 2014 (Started Oct 05, 2011)

  • Effectiveness
    Major (for Crohn's disease)
  • Effectiveness
    Major (for gastrointestinal (GI) bleeding)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Very hard to take
Dosage: 4800 mg Daily
Advice & Tips: For some reason the Oregon Health Plan (new Obama-care insurance) does not cover Asacol HD 800mg TBEC. My recent flare-up may have been exacerbated because I ran out of the medication and couldn't get it refilled. For the last 2 weeks I have been paying out-of-pocket for it and it is EXPENSIVE. I will have to either find another medication option on Monday or work on the appeal process (which looks like a pain in the ass). Until then I will be paying out the whazoo for it because it is the only medication I know of that really can keep me in remission without noticeable side effects.
Cost: $200+ monthly

  • 0 helpful marks

Nov 24, 2012 (Started May 10, 2012)

  • Effectiveness
    Can’t tell (for ulcerative colitis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 11 patient evaluations for Mesalamine