What is Bupropion SR?

Category: Prescription Drugs

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Generic name: Bupropion

Bupropion SR is a sustained release version of bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) used to treat major depressive disorder, including seasonal affective disorder (SAD) and as an adjunct in smoking cessation.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 95 91
Depressed mood 92 66
Persistent depressive disorder (dysthymia) 31 40
Fibromyalgia 19 10
Mild depression 11 6

Show all 55 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 9
Moderate 32
Mild 36
None 84

Commonly reported side effects and conditions associated with Bupropion SR

Side effect Patients
Dry mouth 9
Anxious mood 7
Insomnia 5
Constipation 4
Dizziness 4
Headaches 4

Show all 71 reported side effects

Dosages

Based on patients currently taking Bupropion SR

Dosage Patients
150 mg twice daily 11
150 mg daily 8
100 mg daily 7
300 mg daily 7
400 mg daily 4
100 mg twice daily 2
200 mg daily 2
450 mg daily 2
150 mg/24 hours daily 1
75 mg twice daily 1

See all 17 dosages

Why patients stopped taking Bupropion SR

Multiple reasons could be selected

Reason Patients
Doctor's advice 25
Did not seem to work 24
Side effects too severe 21
Other 15
Course of treatment ended 5
Personal research 5
Expense 4
Change in health plan coverage 1
See all 76 patients who've stopped taking Bupropion SR

Duration

Currently taking Bupropion SR

Duration Patients
Less than 1 month 3
1 - 6 months 2
6 months - 1 year 5
1 - 2 years 7
2 - 5 years 11
5 - 10 years 15
10 years or more 9

Stopped taking Bupropion SR

Duration Patients
Less than 1 month 11
1 - 6 months 16
6 months - 1 year 11
1 - 2 years 14
2 - 5 years 15
5 - 10 years 8
10 years or more 1
Adherence
Adherence Evaluations
Always 123
Usually 33
Sometimes 4
Never taken as prescribed 1
Burden
Burden Evaluations
Very hard to take 6
Somewhat hard to take 14
A little hard to take 22
Not at all hard to take 119
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 0
$50-99 5
$25-49 13
< $25 79
Not specified 63

What people switch to and from

Patients started taking Bupropion SR after stopping:

Treatment Patients
Bupropion (Wellbutrin XL) 4
Lamotrigine (Lamictal) 2
Sertraline (Zoloft) 2
Amitriptyline (Elavil) 1
Atomoxetine (Strattera) 1

Show all 13 treatments patients report switching from

Patients stopped taking Bupropion SR and switched to:

Treatment Patients
Bupropion (Wellbutrin XL) 4
Buspirone (BuSpar) 1
Dextroamphetamine (Dexedrine) 1
Duloxetine (Cymbalta) 1
Escitalopram (Lexapro) 1

Show all 7 treatments patients report switching to

Last updated:

11 patient evaluations for Bupropion SR

Jan 12, 2018 (Started Jun 30, 2017)

  • Effectiveness
    Moderate (for chronic fatigue)
  • Side effects
    Severe (vomiting, nausea)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 100 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks

Sep 19, 2017 (Started Apr 10, 2012)

  • Effectiveness
    Slight (for complex post-traumatic stress disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Mild (headaches)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 150 mg Daily
Cost: < $25 monthly

Sep 17, 2012 (Started Apr 10, 2012)

  • Effectiveness
    Slight (for complex post-traumatic stress disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (headaches)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 300 mg Daily
Advice & Tips: Have someone you trust remind you to take the medicines. I have my wife who reminds me, although I have the medicine in the cupboard by the glasses. When I experience headaches with the buproprion, I take some Aleve or Motrin.
Cost: < $25 monthly

  • 1 helpful mark

Feb 6, 2017 (Started Dec 04, 2009)

  • Effectiveness
    None (for tobacco use disorder)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Can't tell (for bipolar disorder)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines. I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking Wellbutrin. I don't allocate all credit to this med. I take Trintellix also.I have noticed a more consistent level of lower anxiety on Wellbutrin.
Cost: < $25 monthly

Nov 29, 2015 (Started Dec 04, 2009)

  • Effectiveness
    None (for tobacco use disorder)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: Just wanting to update. I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines.
Cost: < $25 monthly

Apr 6, 2011 (Started Dec 04, 2009)

  • Effectiveness
    Can't tell (for bipolar disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking wellbutrin. I don't allocate all credit to this med. I take Pristiq also. So, did it help me quit smoking? not yet.
Cost: < $25 monthly

Oct 25, 2010 (Started Dec 04, 2009)

  • Effectiveness
    Can't tell (for bipolar disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I have noticed a more consistent level of lower anxiety on Wellbutrin. It has also noticeably helped decrease the depression a degree during episodes. I have also decreased my tabacco intake since taking .
Cost: < $25 monthly

  • 1 helpful mark
Last updated:
Showing 3 of 11 patient evaluations for Bupropion SR