What is Moclobemide?

Category: Prescription Drugs

Most popular types: Aurorix


Moclobemide is an antidepressant (monoamine oxidase inhibitor) used for the symptomatic relief of depressive illness.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 9 10
Depressed mood 2 4
Emotional lability 1 0
Mood swings 1 0
Persistent depressive disorder (dysthymia) 1 1

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations

Commonly reported side effects and conditions associated with Moclobemide

Side effect Patients
Anxiety and frustration 2
Dizziness 1
Excessive daytime sleepiness (somnolence) 1
Extreme sedation 1
Fatigue 1
Headaches 1

Show all 18 reported side effects


Based on patients currently taking Moclobemide

Dosage Patients
300 mg twice daily 1

Why patients stopped taking Moclobemide

Multiple reasons could be selected

Reason Patients
Side effects too severe 7
Did not seem to work 6
Doctor's advice 3
Other 1
See all 10 patients who've stopped taking Moclobemide


Currently taking Moclobemide

Duration Patients
2 - 5 years 1

Stopped taking Moclobemide

Duration Patients
Less than 1 month 2
1 - 6 months 3
6 months - 1 year 5
10 years or more 1
Adherence Evaluations
Always 12
Usually 4
Sometimes 0
Never taken as prescribed 0
Burden Evaluations
Very hard to take 2
Somewhat hard to take 1
A little hard to take 7
Not at all hard to take 6
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 0
$50-99 0
$25-49 2
< $25 4
Not specified 9

What people switch to and from

Patients started taking Moclobemide after stopping:

Treatment Patients
Bupropion (Wellbutrin XL) 1
Clonazepam (Klonopin) 1
Quetiapine (Seroquel) 1
Sertraline (Zoloft) 1
Venlafaxine (Effexor XR) 1

Patients stopped taking Moclobemide and switched to:

Treatment Patients
Bupropion (Wellbutrin XL) 1
Escitalopram (Lexapro) 1
Tranylcypromine (Parnate) 1
Last updated:

2 patient evaluations for Moclobemide

Apr 25, 2016 (Started Nov 26, 2015)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
  • Adherence
  • Burden
    Not at all hard to take
Dosage: 300 mg Twice daily
Advice & Tips: The main benefit was breaking through a depression barrier and regaining some normal energy. however it has been stalled and at this point my energy is dropping again yet not my ability to feel pleasure. This is a reversible MAOI, many drug fact sheets say you can not eat foods with tryamine ( aged, fermented foods ) but that applies to non reversible MAOI's. Also with caution I can use antihistamine and decongestants.  I learned the generic off the top of information seems to be based on better safe than sorry rather than science and personal situations. I have access to a clinical pharmacist at my physician's office and here I get the latest up to date and practical advise on medications.

  • 0 helpful marks

Apr 20, 2012 (Started Mar 29, 2012)

  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    None (for depression with anxiety)
  • Side effects
    Severe (anxiety and frustration, panic about future, panic attacks)
  • Adherence
  • Burden
    A little hard to take
Dosage: 300 mg Daily
Advice & Tips: I had to stop taking this, because the med caused me to have increased anxiety, panic attacks and nightly wakings with unbearable anxiety. My consumption of benzodiazepimes increased immensely during the treatment.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 2 of 2 patient evaluations for Moclobemide