What is Tizanidine?

Category: Prescription Drugs

Most popular types: Zanaflex Sirdalud Sirdalud Retard Show all

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Tizanidine hydrochloride is a skeletal muscle relaxant used for treatment of muscle spasticity. It may also be used for tension headaches, low back pain, and trigeminal neuralgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Stiffness/Spasticity 803 280
Muscle spasms 600 221
Fibromyalgia 296 99
Muscle pain 86 30
Pain 80 42
Muscle spasms in neck and shoulders 56 12

Show all 155 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 60
Moderate 147
Mild 157
None 238

Commonly reported side effects and conditions associated with Tizanidine

Side effect Patients
Sleepiness 72
Drowsiness 46
Dry mouth 46
Fatigue 24
Excessive daytime sleepiness (somnolence) 19
Dry eyes 17

Show all 114 reported side effects

Dosages

Based on patients currently taking Tizanidine

Dosage Patients
4 mg daily 45
8 mg daily 19
12 mg daily 18
4mg as needed 18
2 mg daily 16
4 mg three times daily 16
2 mg three times daily 14
4 mg twice daily 8
2 mg twice daily 7
6 mg daily 6

See all 35 dosages

Why patients stopped taking Tizanidine

Multiple reasons could be selected

Reason Patients
Did not seem to work 139
Side effects too severe 76
Other 72
Doctor's advice 69
Course of treatment ended 19
Personal research 15
Expense 12
Change in health plan coverage 9
See all 337 patients who’ve stopped taking Tizanidine

Duration

Currently taking Tizanidine

Duration Patients
Less than 1 month 2
1 - 6 months 18
6 months - 1 year 21
1 - 2 years 25
2 - 5 years 65
5 - 10 years 63
10 years or more 27

Stopped taking Tizanidine

Duration Patients
Less than 1 month 51
1 - 6 months 94
6 months - 1 year 53
1 - 2 years 56
2 - 5 years 51
5 - 10 years 25
10 years or more 9
Adherence
Adherence Evaluations
Always 415
Usually 115
Sometimes 54
Never taken as prescribed 18
Burden
Burden Evaluations
Very hard to take 29
Somewhat hard to take 33
A little hard to take 90
Not at all hard to take 450
Cost per month
Cost per month Evaluations
$200+ 3
$100-199 0
$50-99 15
$25-49 40
< $25 332
Not specified 212

What people switch to and from

Patients started taking Tizanidine after stopping:

Treatment Patients
Cyclobenzaprine (Flexeril) 27
Baclofen (Mylan-Baclofen) 22
Carisoprodol (Soma) 8
Diazepam (Valium) 3
Hydrocodone-Acetaminophen (Vicodin) 3

Show all 19 treatments patients report switching from

Patients stopped taking Tizanidine and switched to:

Treatment Patients
Baclofen (Mylan-Baclofen) 14
Cyclobenzaprine (Flexeril) 3
Baclofen Intrathecal pump (Lioresal) 2
Methocarbamol (Robaxin) 2
Amlodipine (Norvasc) 1

Show all 16 treatments patients report switching to

Last updated:

86 patient evaluations for Tizanidine

460 members have decided to share their profiles only with other members of PatientsLikeMe.

thjuland
647 thumb
thjuland
Sex: M
Data Quality: 3 stars
Sensation: Mild
Overall: Mild
Cognition: moderate
Vision: moderate
Speech: mild
Swallowing: mild
Upper limb: mild
Walking: moderate
I am: vg
I have:
MS

See thjuland's full Tizanidine history

Nov 30, 2016 (Started Mar 06, 2014)

  • Effectiveness
    Major (for Stiffness/Spasticity)
  • Side effects
    Mild (Sleepiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 24 mg Daily
Advice & Tips: I increased the dosage to 6 mg four times a day, because of increased left leg/foot spasticity in the evening.
Cost: < $25 monthly

Mar 25, 2016 (Started Mar 06, 2014)

  • Effectiveness
    Major (for Stiffness/Spasticity)
  • Side effects
    Mild (Sleepiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 16 mg Daily
Advice & Tips: Still effective for relief of spasticity and I usually bypass the sleepiness by spacing doses at 4 hour intervals.
Cost: < $25 monthly

Sep 21, 2015 (Started Mar 06, 2014)

  • Effectiveness
    Major (for Stiffness/Spasticity)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 16 mg Daily
Advice & Tips: it's very effective for relief of spasticity, unfortunately it puts me into a deep sleep.
Cost: < $25 monthly

Oct 8, 2014 (Started Mar 06, 2014)

  • Effectiveness
    Major (for Stiffness/Spasticity)
  • Side effects
    Mild (Sleepiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 12 mg Daily
Advice & Tips: none, i sleep as needed.
Cost: < $25 monthly

  • 0 helpful marks
Srs2388
85822 thumb
Srs2388
Data Quality: 1 star
  • Gender: M
  • Age: 28y
  • Duration: ? yrs
Quality of life:
  • Mental: Severe
  • Physical: Severe
1 seizure
10 weeks ago
I am: b
I have:
Epilepsy

See Srs2388's full Tizanidine history

Apr 13, 2016 (Started Apr 15, 2016)

  • Effectiveness
    Slight (for Stiffness/Spasticity)
  • Side effects
    Severe (Dry mouth, Drowsiness)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 4 mg Four times daily
Advice & Tips: If you have to be alert, avoid it. Keep a drink close.

  • 0 helpful marks
Keeper of the Flame
10493 thumb
Keeper of the Flame
Gender: F
Data Quality: 3 stars
Pain: Some
Fatigue: Some
Sleep: Most
Stiffness: Some
function: Some
external_stress: Little
Stickman: some
Description:F58y
CFS:?y
FM:8y Dx
I am: b
I have:
Fibromyalgia

See Keeper of the Flame's full Tizanidine history

Mar 13, 2016 (Started Mar 01, 2016)

  • Effectiveness
    Moderate (for Muscle spasms)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 8 mg Twice daily
Advice & Tips: I really liked taking Flexeril but my insurance will no longer cover it as they say it causes falls. I will give the Zanaflex a try to see how it works for the next 6 months and then we will see and I will talk to my doctor if I don't think it is a good choice or I need an increase in the dosage as I don't feel anything from the dosage that I am currently taking.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 86 patient evaluations for Tizanidine