What is Tizanidine?

Category: Prescription Drugs

Most popular types: Zanaflex Sirdalud Sirdalud Retard Show all

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Tizanidine hydrochloride is a skeletal muscle relaxant used for treatment of muscle spasticity. It may also be used for tension headaches, low back pain, and trigeminal neuralgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Stiffness/Spasticity 821 293
Muscle spasms 624 232
Fibromyalgia 308 105
Muscle pain 86 30
Pain 82 44
Muscle spasms in neck and shoulders 56 12

Show all 157 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 62
Moderate 155
Mild 165
None 245

Commonly reported side effects and conditions associated with Tizanidine

Side effect Patients
Sleepiness 72
Drowsiness 51
Dry mouth 46
Fatigue 25
Excessive daytime sleepiness (somnolence) 19
Dry eyes 17

Show all 120 reported side effects

Dosages

Based on patients currently taking Tizanidine

Dosage Patients
4 mg daily 53
8 mg daily 26
2 mg daily 24
4mg as needed 20
12 mg daily 19
4 mg three times daily 17
4 mg twice daily 14
2 mg three times daily 13
8 mg three times daily 8
6 mg daily 7

See all 36 dosages

Why patients stopped taking Tizanidine

Multiple reasons could be selected

Reason Patients
Did not seem to work 145
Side effects too severe 84
Other 71
Doctor's advice 68
Course of treatment ended 19
Personal research 15
Expense 12
Change in health plan coverage 9
See all 349 patients who’ve stopped taking Tizanidine

Duration

Currently taking Tizanidine

Duration Patients
Less than 1 month 2
1 - 6 months 16
6 months - 1 year 28
1 - 2 years 39
2 - 5 years 74
5 - 10 years 70
10 years or more 33

Stopped taking Tizanidine

Duration Patients
Less than 1 month 53
1 - 6 months 96
6 months - 1 year 54
1 - 2 years 57
2 - 5 years 55
5 - 10 years 26
10 years or more 10
Adherence
Adherence Evaluations
Always 433
Usually 117
Sometimes 56
Never taken as prescribed 21
Burden
Burden Evaluations
Very hard to take 30
Somewhat hard to take 33
A little hard to take 92
Not at all hard to take 472
Cost per month
Cost per month Evaluations
$200+ 3
$100-199 0
$50-99 15
$25-49 41
< $25 348
Not specified 220

What people switch to and from

Patients started taking Tizanidine after stopping:

Treatment Patients
Cyclobenzaprine (Flexeril) 32
Baclofen (Mylan-Baclofen) 23
Carisoprodol (Soma) 8
Diazepam (Valium) 3
Hydrocodone-Acetaminophen (Vicodin) 3

Show all 23 treatments patients report switching from

Patients stopped taking Tizanidine and switched to:

Treatment Patients
Baclofen (Mylan-Baclofen) 17
Cyclobenzaprine (Flexeril) 5
Baclofen Intrathecal pump (Lioresal) 2
Clonazepam (Klonopin) 2
Diazepam (Valium) 2

Show all 16 treatments patients report switching to

Last updated:

86 patient evaluations for Tizanidine

480 members have decided to share their profiles only with other members of PatientsLikeMe.

thjuland
647 thumb
thjuland
Sex: M
Data Quality: 3 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: none
Speech: none
Swallowing: mild
Upper limb: mild
Walking: moderate
I am: n
I have:
MS

See thjuland's full Tizanidine history

Nov 30, 2016 (Started Mar 06, 2014)

  • Effectiveness
    Major (for Stiffness/Spasticity)
  • Side effects
    Mild (Sleepiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 24 mg Daily
Advice & Tips: I increased the dosage to 6 mg four times a day, because of increased left leg/foot spasticity in the evening.
Cost: < $25 monthly

Mar 25, 2016 (Started Mar 06, 2014)

  • Effectiveness
    Major (for Stiffness/Spasticity)
  • Side effects
    Mild (Sleepiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 16 mg Daily
Advice & Tips: Still effective for relief of spasticity and I usually bypass the sleepiness by spacing doses at 4 hour intervals.
Cost: < $25 monthly

Sep 21, 2015 (Started Mar 06, 2014)

  • Effectiveness
    Major (for Stiffness/Spasticity)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 16 mg Daily
Advice & Tips: it's very effective for relief of spasticity, unfortunately it puts me into a deep sleep.
Cost: < $25 monthly

Oct 8, 2014 (Started Mar 06, 2014)

  • Effectiveness
    Major (for Stiffness/Spasticity)
  • Side effects
    Mild (Sleepiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 12 mg Daily
Advice & Tips: none, i sleep as needed.
Cost: < $25 monthly

  • 0 helpful marks
Srs2388
85822 thumb
Srs2388
Data Quality: 1 star
  • Gender: M
  • Age: 29y
  • Duration: ? yrs
Quality of life:
  • Mental: Severe
  • Physical: Severe
2 seizures
6 weeks ago
I am: vb
I have:
Epilepsy

See Srs2388's full Tizanidine history

Apr 13, 2016 (Started Apr 15, 2016)

  • Effectiveness
    Slight (for Stiffness/Spasticity)
  • Side effects
    Severe (Dry mouth, Drowsiness)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 4 mg Four times daily
Advice & Tips: If you have to be alert, avoid it. Keep a drink close.

  • 0 helpful marks
Keeper of the Flame
10493 thumb
Keeper of the Flame
Gender: F
Data Quality: 3 stars
Pain: Most
Fatigue: Most
Sleep: Most
Stiffness: All
function: Little
external_stress: Some
Stickman: most
Description:F59y
CFS:?y
FM:8y Dx
I am: g
I have:
Fibromyalgia

See Keeper of the Flame's full Tizanidine history

Mar 13, 2016 (Started Mar 01, 2016)

  • Effectiveness
    Moderate (for Muscle spasms)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 8 mg Twice daily
Advice & Tips: I really liked taking Flexeril but my insurance will no longer cover it as they say it causes falls. I will give the Zanaflex a try to see how it works for the next 6 months and then we will see and I will talk to my doctor if I don't think it is a good choice or I need an increase in the dosage as I don't feel anything from the dosage that I am currently taking.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 86 patient evaluations for Tizanidine