What is Milnacipran?

Category: Prescription Drugs

Most popular types: Savella Ixel

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Milnacipran is a serotonin/norepinephrine reuptake inhibitor (SNRI) antidepressant. It is used in the treatment of depression and has demonstrated significant improvements in multiple aspects of fibromyalgia, including pain, patient global assessment and physical function.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 1,117 633
Pain 173 97
Depressed mood 97 54
Whole body joint ache 23 10
Fatigue 14 7

Show all 56 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 198
Moderate 159
Mild 167
None 160

Commonly reported side effects and conditions associated with Milnacipran

Side effect Patients
Nausea 90
Excessive sweating 36
Headaches 30
Hot flashes 29
Constipation 27
Dizziness 19

Show all 232 reported side effects

Dosages

Based on patients currently taking Milnacipran

Dosage Patients
100 mg twice daily 14
100 mg daily 13
50 mg twice daily 9
50 mg daily 5
12.5 mg daily 3
200 mg daily 3
25 mg twice daily 2
daily 2
12.5 mg twice daily 1
25 mg daily 1

See all 13 dosages

Why patients stopped taking Milnacipran

Multiple reasons could be selected

Reason Patients
Side effects too severe 264
Did not seem to work 175
Doctor's advice 75
Expense 49
Other 34
Change in health plan coverage 17
Personal research 14
Course of treatment ended 5
See all 444 patients who've stopped taking Milnacipran

Duration

Currently taking Milnacipran

Duration Patients
Less than 1 month 1
1 - 6 months 2
6 months - 1 year 4
1 - 2 years 9
2 - 5 years 10
5 - 10 years 30

Stopped taking Milnacipran

Duration Patients
Less than 1 month 112
1 - 6 months 189
6 months - 1 year 52
1 - 2 years 44
2 - 5 years 37
5 - 10 years 8
10 years or more 2
Adherence
Adherence Evaluations
Always 590
Usually 58
Sometimes 10
Never taken as prescribed 26
Burden
Burden Evaluations
Very hard to take 53
Somewhat hard to take 57
A little hard to take 109
Not at all hard to take 465
Cost per month
Cost per month Evaluations
$200+ 15
$100-199 40
$50-99 86
$25-49 159
< $25 165
Not specified 219

What people switch to and from

Patients started taking Milnacipran after stopping:

Treatment Patients
Duloxetine (Cymbalta) 27
Pregabalin (Lyrica) 18
Gabapentin (Neurontin) 5
Nortriptyline (Pamelor) 2
Citalopram (Celexa) 1

Show all 13 treatments patients report switching from

Patients stopped taking Milnacipran and switched to:

Treatment Patients
Duloxetine (Cymbalta) 7
Gabapentin (Neurontin) 4
Pregabalin (Lyrica) 4
Naltrexone (Low Dose Naltrexone (LDN)) 2
Topiramate (Topamax) 2

Show all 17 treatments patients report switching to

Last updated:

74 patient evaluations for Milnacipran

Sep 15, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Moderate (weight gain, elevated blood pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Cost: $25-49 monthly

Jul 28, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Moderate (weight gain, elevated blood pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Cost: $25-49 monthly

Sep 15, 2014 (Started Jul 01, 2011)

  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks

Jun 15, 2015 (Started Jul 01, 2010)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Mild (weight gain)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 100 mg Daily
Advice & Tips: I felt that Savella was very effective in managing FM symptoms, however, with Obamacare, it was too expensive to keep taking it. I gradually weened off the medication, and am now using supplements from Melaleuca and JuicePlus and am doing just as well.
Cost: $200+ monthly

  • 1 helpful mark

Dec 21, 2014 (Started Oct 01, 2009)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    Moderate (insomnia, nausea)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: $50-99 monthly

Sep 22, 2013 (Started Oct 01, 2009)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    Mild (insomnia, nausea)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: $50-99 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 74 patient evaluations for Milnacipran