What is Milnacipran?

Category: Prescription Drugs

Most popular types: Savella Ixel

false

Milnacipran is a serotonin/norepinephrine reuptake inhibitor (SNRI) antidepressant. It is used in the treatment of depression and has demonstrated significant improvements in multiple aspects of fibromyalgia, including pain, patient global assessment and physical function.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 1,091 619
Pain 167 97
Depressed mood 94 54
Whole body joint ache 23 10
Fatigue 14 7
Major Depressive Disorder 8 5

Show all 67 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 194
Moderate 156
Mild 167
None 153

Commonly reported side effects and conditions associated with Milnacipran

Side effect Patients
Nausea 91
Excessive sweating 34
Headaches 30
Hot flashes 28
Constipation 27
Dizziness 23

Show all 231 reported side effects

Dosages

Based on patients currently taking Milnacipran

Dosage Patients
100 mg daily 15
50 mg twice daily 14
100 mg twice daily 13
200 mg daily 6
25 mg twice daily 5
12.5 mg twice daily 4
12.5 mg daily 3
50 mg daily 3
25 mg daily 2
150 mg daily 2

See all 17 dosages

Why patients stopped taking Milnacipran

Multiple reasons could be selected

Reason Patients
Side effects too severe 261
Did not seem to work 171
Doctor's advice 75
Expense 48
Other 32
Change in health plan coverage 16
Personal research 14
Course of treatment ended 5
See all 436 patients who’ve stopped taking Milnacipran

Duration

Currently taking Milnacipran

Duration Patients
1 - 6 months 9
6 months - 1 year 7
1 - 2 years 10
2 - 5 years 16
5 - 10 years 34

Stopped taking Milnacipran

Duration Patients
Less than 1 month 108
1 - 6 months 188
6 months - 1 year 51
1 - 2 years 43
2 - 5 years 36
5 - 10 years 8
10 years or more 2
Adherence
Adherence Evaluations
Always 577
Usually 57
Sometimes 10
Never taken as prescribed 26
Burden
Burden Evaluations
Very hard to take 51
Somewhat hard to take 56
A little hard to take 107
Not at all hard to take 456
Cost per month
Cost per month Evaluations
$200+ 14
$100-199 40
$50-99 85
$25-49 160
< $25 160
Not specified 211

What people switch to and from

Patients started taking Milnacipran after stopping:

Treatment Patients
Duloxetine (Cymbalta) 20
Pregabalin (Lyrica) 11
Gabapentin (Neurontin) 3
Nortriptyline (Pamelor) 2
Citalopram (Celexa) 1

Show all 11 treatments patients report switching from

Patients stopped taking Milnacipran and switched to:

Treatment Patients
Duloxetine (Cymbalta) 5
Pregabalin (Lyrica) 4
Gabapentin (Neurontin) 2
Topiramate (Topamax) 2
Tramadol (Ultram) 2

Show all 13 treatments patients report switching to

Last updated:

73 patient evaluations for Milnacipran

506 members have decided to share their profiles only with other members of PatientsLikeMe.

AnnieOakley
9024 thumb
AnnieOakley
Gender: F
Data Quality: 1 star
Pain: Little
Fatigue: All
Sleep: Little
Stiffness: Most
function: Some
external_stress: Most
Stickman: some
Description:F44y
FM:8y Dx
I am: n
I have:
Fibromyalgia

See AnnieOakley's full Milnacipran history

Sep 15, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Slight (for Fibromyalgia)
  • Effectiveness
    Slight (for Depressed mood)
  • Side effects
    Moderate (Weight gain, Elevated blood pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Cost: $25-49 monthly

Jul 28, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Slight (for Fibromyalgia)
  • Effectiveness
    Slight (for Depressed mood)
  • Side effects
    Moderate (Weight gain, Elevated blood pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Cost: $25-49 monthly

Sep 15, 2014 (Started Jul 01, 2011)

  • Effectiveness
    Slight (for Fibromyalgia)
  • Effectiveness
    Slight (for Depressed mood)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks
Powder211
8856 thumb
Powder211
Gender: F
Data Quality: 0 stars
Pain: Some
Fatigue: Most
Sleep: Some
Stiffness: Most
function: Some
external_stress: All
Stickman: some
Description:F49y
FM:10y Dx
CFS:9y Dx
I am: n
I have:
Fibromyalgia

See Powder211's full Milnacipran history

Jun 15, 2015 (Started Jul 01, 2010)

  • Effectiveness
    Major (for Fibromyalgia)
  • Side effects
    Mild (Weight gain)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 100 mg Daily
Advice & Tips: I felt that Savella was very effective in managing FM symptoms, however, with Obamacare, it was too expensive to keep taking it. I gradually weened off the medication, and am now using supplements from Melaleuca and JuicePlus and am doing just as well.
Cost: $200+ monthly

  • 1 helpful mark
KAB62
Portrait default thumb
KAB62
Gender: F
Data Quality: 1 star
Pain: Some
Fatigue: Most
Sleep: All
Stiffness: Most
function: Some
external_stress: Most
Stickman: most
Description:F54y
FM:15y Dx
I am: b
I have:
Fibromyalgia

See KAB62's full Milnacipran history

Dec 21, 2014 (Started Oct 01, 2009)

  • Effectiveness
    Moderate (for Fibromyalgia)
  • Side effects
    Moderate (Insomnia, Nausea)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: $50-99 monthly

Sep 22, 2013 (Started Oct 01, 2009)

  • Effectiveness
    Moderate (for Fibromyalgia)
  • Side effects
    Mild (Insomnia, Nausea)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Cost: $50-99 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 73 patient evaluations for Milnacipran