What is Levetiracetam?

Category: Prescription Drugs

Most popular types: Keppra Keppra XR

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Levetiracetam is is an anticonvulsant used in combination with other medications to treat partial onset, myoclonic, and/or primary generalized tonic-clonic seizures.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 1,262 862
Seizures 187 128
Seizures (grand mal or tonic-clonic) 103 72
Seizures (complex partial) 41 38
Seizures (partial focal) 19 3
Pain 14 1

Show all 91 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 165
Moderate 267
Mild 288
None 297

Commonly reported side effects and conditions associated with Levetiracetam

Side effect Patients
Fatigue 40
Drowsiness 36
Tiredness 33
Depressed mood 28
Dizziness 28
Excessive daytime sleepiness (somnolence) 28

Show all 332 reported side effects

Dosages

Based on patients currently taking Levetiracetam

Dosage Patients
500 mg twice daily 22
1,000 mg daily 9
1,000 mg twice daily 9
2,000 mg daily 9
1,500 mg daily 8
3,000 mg daily 8
500 mg daily 7
750 mg twice daily 7
1,000 mg twice daily 7
1,500 mg twice daily 7

See all 42 dosages

Why patients stopped taking Levetiracetam

Multiple reasons could be selected

Reason Patients
Side effects too severe 186
Did not seem to work 145
Doctor's advice 133
Other 43
Expense 22
Course of treatment ended 21
Personal research 14
Change in health plan coverage 6
See all 386 patients who've stopped taking Levetiracetam

Duration

Currently taking Levetiracetam

Duration Patients
1 - 6 months 3
6 months - 1 year 6
1 - 2 years 18
2 - 5 years 26
5 - 10 years 59
10 years or more 36

Stopped taking Levetiracetam

Duration Patients
Less than 1 month 84
1 - 6 months 99
6 months - 1 year 61
1 - 2 years 52
2 - 5 years 67
5 - 10 years 22
10 years or more 6
Adherence
Adherence Evaluations
Always 916
Usually 69
Sometimes 10
Never taken as prescribed 22
Burden
Burden Evaluations
Very hard to take 58
Somewhat hard to take 70
A little hard to take 151
Not at all hard to take 738
Cost per month
Cost per month Evaluations
$200+ 64
$100-199 26
$50-99 72
$25-49 78
< $25 437
Not specified 340

What people switch to and from

Patients started taking Levetiracetam after stopping:

Treatment Patients
Phenytoin (Dilantin) 20
Divalproex sodium (Depakote) 11
Lamotrigine (Lamictal) 9
Oxcarbazepine (Trileptal) 6
Carbamazepine (Tegretol) 5

Show all 16 treatments patients report switching from

Patients stopped taking Levetiracetam and switched to:

Treatment Patients
Lamotrigine (Lamictal) 11
Lacosamide (Vimpat) 7
Carbamazepine (Tegretol) 6
Topiramate (Topamax) 6
Zonisamide (Zonegran) 4

Show all 18 treatments patients report switching to

Last updated:

94 patient evaluations for Levetiracetam

Jan 28, 2011 (Started Jan 09, 2000)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2000 mg Daily
Advice & Tips: Keppra XR worked much better than Keppra. No rage, no side effects after the first two weeks, sad to say because of insurance I will have to switch back to generic Keppra.
Cost: $100-199 monthly
Side effects: rage

Jan 16, 2011 (Started Jan 09, 2000)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2000 mg Daily
Advice & Tips: Talk to your doctor about your Keppra. XR taken once a day really helped me overcome the side effects and burden of taking pills four times a day. It's really worked well with other AED's to keep me seizure free. Always work with your doctor and be sure your doctor works with you. Working together you have a better chance at seizure control.
Cost: $100-199 monthly
Side effects: rage

Dec 15, 2010 (Started Jan 09, 2000)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2000 mg Daily
Advice & Tips: Seizure free and side effect free for 6 weeks. I kept moving forward, using a journal, and trying new meds until I found a cocktail that was right for me.
Cost: < $25 monthly
Side effects: rage

Nov 5, 2010 (Started Jan 09, 2000)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    Moderate (rage)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2000 mg Daily
Advice & Tips: Keppra XR may be causing side effect of being emotionally over sensitive. I become saddened easily.
Cost: < $25 monthly
Side effects: rage

Aug 21, 2010 (Started Jan 09, 2000)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2000 mg Daily
Advice & Tips: Took this medication for years. Am wondering now, is it really making a difference?
Cost: < $25 monthly
Side effects: rage

Aug 10, 2010 (Started Jan 09, 2000)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2000 mg Daily
Advice & Tips: After my body adjusted to Keppra it was as if I finally found one of the meds my body and brain needs to manage seizures.
Cost: < $25 monthly
Side effects: rage

Apr 1, 2010 (Started Jan 09, 2000)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2000 mg Daily
Advice & Tips: Keppra XR is one of the best treatments for me. Easy to remember to use, the only possible side effect I notice is an inability to lose weight.
Cost: < $25 monthly
Side effects: rage

  • 2 helpful marks

Jan 13, 2010 (Started Dec 15, 2008)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1000 mg Daily
Advice & Tips: I have tried almost every anti-seizure control medicene over my lifetime and the one thing I have noticed is that the time release types work best for me. I am never happy with the side-effects of any of them but Keppra so far seems to have the fewest and most mild of any of them I have experienced.

  • 1 helpful mark

Mar 23, 2010 (Started Jan 13, 2009)

  • Effectiveness
    Moderate (for epilepsy)
  • Side effects
    Severe (panic attack with anger, fear)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Keppra XR caused me to be in panic, each time I took it the panic got worse until I was in shear terror. I call the doctor the next day and he switched me to Lamictral.
Side effects: panic attack with anger, fear

  • 1 helpful mark
Last updated:
Showing 3 of 94 patient evaluations for Levetiracetam