What is Valproate Sodium?

Category: Prescription Drugs

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Sodium valproate or valproate sodium is the sodium salt of valproic acid and is an anticonvulsant used in the treatment of epilepsy and bipolar disorder, as well as other psychiatric conditions requiring the administration of a mood stabilizer.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 95 56
Bipolar disorder 61 71
Bipolar manic episodes 23 26
Bipolar II disorder 10 5
Fibromyalgia 5 2
Anxious mood 4 1

Show all 55 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 28
Moderate 52
Mild 33
None 58

Commonly reported side effects and conditions associated with Valproate Sodium

Side effect Patients
Weight gain 28
Drowsiness 9
Hair loss 8
Fatigue 7
Nausea 6
Sleepiness 6

Show all 82 reported side effects

Dosages

Based on patients currently taking Valproate Sodium

Dosage Patients
500 mg daily 2
800 mg daily 2
600 mg twice daily 2
2,000 mg daily 2
1 tablet(s) daily 1
2 tablet(s) daily 1
3 mcg daily 1
15 mg daily 1
500 mg weekly 1
150 mg daily 1

See all 20 dosages

Why patients stopped taking Valproate Sodium

Multiple reasons could be selected

Reason Patients
Side effects too severe 30
Doctor's advice 21
Did not seem to work 20
Other 13
Course of treatment ended 5
Personal research 3
Expense 2
Change in health plan coverage 1
See all 64 patients who've stopped taking Valproate Sodium

Duration

Currently taking Valproate Sodium

Duration Patients
6 months - 1 year 1
1 - 2 years 1
2 - 5 years 6
5 - 10 years 11
10 years or more 6

Stopped taking Valproate Sodium

Duration Patients
Less than 1 month 13
1 - 6 months 16
6 months - 1 year 7
1 - 2 years 8
2 - 5 years 11
5 - 10 years 7
10 years or more 3
Adherence
Adherence Evaluations
Always 129
Usually 31
Sometimes 7
Never taken as prescribed 4
Burden
Burden Evaluations
Very hard to take 13
Somewhat hard to take 21
A little hard to take 40
Not at all hard to take 97
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 3
$50-99 3
$25-49 5
< $25 51
Not specified 109

What people switch to and from

Patients started taking Valproate Sodium after stopping:

Treatment Patients
Lamotrigine (Lamictal) 4
Lithium Carbonate (Lithium Carbonate ER) 4
Carbamazepine (Tegretol) 2
Quetiapine (Seroquel) 2
Alprazolam (Xanax) 1

Show all 12 treatments patients report switching from

Patients stopped taking Valproate Sodium and switched to:

Treatment Patients
Carbamazepine (Tegretol) 3
Lamotrigine (Lamictal) 2
Levetiracetam (Keppra) 1
Lithium Carbonate (Lithium Carbonate ER) 1
Paroxetine (Paxil) 1

Show all 10 treatments patients report switching to

Last updated:

7 patient evaluations for Valproate Sodium

Feb 20, 2010 (Started Oct 01, 2009)

  • Effectiveness
    Major (for depression with anxiety)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 900 mg Daily
Advice & Tips: It has helped me to stabilize my mood swings a lot. I can concentrate much better. I take it in combo with tianeptine (antidepressant), but I have to tell, that Orfiril alone is also quite capable when it comes to depression prevention. I perceive no negative side effects.
Cost: < $25 monthly

  • 0 helpful marks

Jan 1, 2010 (Started Jun 01, 2008)

  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 1000 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Aug 12, 2010 (Started Jul 18, 2003)

  • Effectiveness
    Major (for mood)
  • Side effects
    Severe (weight gain)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 2000 mg Daily
Advice & Tips: hair goes curly,weight gain is excessive helps moods
Side effects: weight gain

Jul 20, 2010 (Started Jul 18, 2003)

  • Effectiveness
    Major (for mood)
  • Side effects
    Moderate (weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1500 mg Daily
Advice & Tips: this drug is exellent for stabilising mood but does cause weight gain.
Side effects: weight gain

  • 0 helpful marks
Last updated:
Showing 3 of 7 patient evaluations for Valproate Sodium