What is Mesalamine?

Category: Prescription Drugs

Most popular types: Pentasa Asacol Lialda Show all

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Mesalamine, a derivative of 5-aminosalicylic acid, is an anti-inflammatory agent. It can be used to treat ulcerative colitis and Crohn’s disease. It can be taken orally or applied rectally to help treat the inflammation associated with these conditions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Crohn's disease 262 107
Ulcerative colitis 194 102
Microscopic colitis 7 5
Diarrhea 6 6
Chronic diarrhea 3 2

Show all 22 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 14
Moderate 26
Mild 33
None 152

Commonly reported side effects and conditions associated with Mesalamine

Side effect Patients
Diarrhea 7
Headaches 6
Nausea 6
Hair loss 5
Fatigue 4
Abdominal bloating 2

Show all 74 reported side effects

Dosages

Based on patients currently taking Mesalamine

Dosage Patients
2.4 g daily 4
400 mg daily 4
2,400 mg daily 4
4,800 mg daily 4
2,000 mg daily 3
800 mg three times daily 3
3,000 mg daily 3
1,000 mg four times daily 3
1.5 g daily 2
4.8 g daily 2

See all 39 dosages

Why patients stopped taking Mesalamine

Multiple reasons could be selected

Reason Patients
Did not seem to work 103
Doctor's advice 60
Side effects too severe 37
Other 30
Expense 18
Course of treatment ended 17
Change in health plan coverage 9
Personal research 9
See all 185 patients who've stopped taking Mesalamine

Duration

Currently taking Mesalamine

Duration Patients
1 - 6 months 3
6 months - 1 year 2
1 - 2 years 5
2 - 5 years 22
5 - 10 years 19
10 years or more 14

Stopped taking Mesalamine

Duration Patients
Less than 1 month 45
1 - 6 months 43
6 months - 1 year 20
1 - 2 years 27
2 - 5 years 21
5 - 10 years 19
10 years or more 20
Adherence
Adherence Evaluations
Always 165
Usually 43
Sometimes 7
Never taken as prescribed 10
Burden
Burden Evaluations
Very hard to take 17
Somewhat hard to take 34
A little hard to take 53
Not at all hard to take 121
Cost per month
Cost per month Evaluations
$200+ 14
$100-199 9
$50-99 9
$25-49 26
< $25 57
Not specified 110

What people switch to and from

Patients started taking Mesalamine after stopping:

Treatment Patients
Sulfasalazine (Salazopyrin) 14
Mesalamine (Pentasa) 7
Balsalazide (Colazal) 3
Infliximab (Remicade) 2
Mercaptopurine (Purinethol) 2

Show all 8 treatments patients report switching from

Patients stopped taking Mesalamine and switched to:

Treatment Patients
Infliximab (Remicade) 8
Mesalamine (Pentasa) 7
Sulfasalazine (Salazopyrin) 7
Adalimumab (Humira) 4
Balsalazide (Colazal) 4

Show all 13 treatments patients report switching to

Last updated:

11 patient evaluations for Mesalamine

Jul 1, 2012 (Started Jul 01, 2011)

  • Effectiveness
    Slight (for Crohn's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 1000 mg Daily
Advice & Tips: If it helps you, go for it but it never really helped me.
Cost: < $25 monthly

  • 0 helpful marks

Mar 2, 2012 (Started May 29, 2000)

  • Effectiveness
    Major (for ulcerative colitis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2000 mg Daily
Advice & Tips: Pills are rather large
Cost: < $25 monthly

  • 0 helpful marks

May 19, 2010 (Started May 20, 2006)

  • Effectiveness
    None (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Advice & Tips: Asacol simply doesn't work for me. Never has. It seemed to have no effect at all. That includes side effects.
Cost: < $25 monthly

May 1, 2009 (Started May 20, 2006)

  • Effectiveness
    None (for Other)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Very hard to take
Dosage: 4800 mg Daily
Advice & Tips: For some people this may work. Not for me.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 11 patient evaluations for Mesalamine