What is Clomipramine?

Category: Prescription Drugs

Most popular types: Anafranil

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See also: Anafranil

A tricyclic antidepressant used to treat people with obsessive-compulsive disorder (OCD). It is also used in the treatment of depression, panic attacks and pain.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Obsessive-compulsive disorder 44 21
Depressed mood 24 15
Obsessive thinking 14 7
Major depressive disorder 10 5
Generalized anxiety disorder 2 1

Show all 27 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 10
Moderate 19
Mild 12
None 12

Commonly reported side effects and conditions associated with Clomipramine

Side effect Patients
Dry mouth 11
Weight gain 6
Decreased sex drive (libido) 3
Constipation 2
Decreased appetite 2
Excessive daytime sleepiness (somnolence) 2

Show all 47 reported side effects

Dosages

Based on patients currently taking Clomipramine

Dosage Patients
25 mg daily 5
150 mg daily 2
50 mg daily 1
75 mg daily 1
100 mg daily 1
75 mg twice daily 1

Why patients stopped taking Clomipramine

Multiple reasons could be selected

Reason Patients
Did not seem to work 23
Side effects too severe 23
Doctor's advice 15
Other 9
Personal research 3
Change in health plan coverage 1
Course of treatment ended 1
Expense 1
See all 51 patients who've stopped taking Clomipramine

Duration

Currently taking Clomipramine

Duration Patients
1 - 6 months 1
6 months - 1 year 1
2 - 5 years 1
5 - 10 years 4
10 years or more 4

Stopped taking Clomipramine

Duration Patients
Less than 1 month 10
1 - 6 months 7
6 months - 1 year 8
1 - 2 years 7
2 - 5 years 16
5 - 10 years 1
10 years or more 2
Adherence
Adherence Evaluations
Always 42
Usually 6
Sometimes 2
Never taken as prescribed 3
Burden
Burden Evaluations
Very hard to take 5
Somewhat hard to take 6
A little hard to take 9
Not at all hard to take 33
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 0
$50-99 2
$25-49 2
< $25 16
Not specified 32

What people switch to and from

Patients started taking Clomipramine after stopping:

Treatment Patients
Duloxetine (Cymbalta) 2
Fluoxetine (Prozac) 2
Alprazolam (Xanax) 1
Atomoxetine (Strattera) 1
Bromazepam (Lexotanil) 1

Show all 16 treatments patients report switching from

Patients stopped taking Clomipramine and switched to:

Treatment Patients
Bupropion (Wellbutrin XL) 2
Fluoxetine (Prozac) 2
Sertraline (Zoloft) 2
Duloxetine (Cymbalta) 1
Fluvoxamine (Luvox) 1

Show all 12 treatments patients report switching to

Last updated:

3 patient evaluations for Clomipramine

Apr 15, 2012 (Started Dec 21, 2010)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Mild (hunger, tiredness, dry mouth, apathy, excessive daytime sleepiness (somnolence), constipation)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: As needed
Cost: < $25 monthly
Side effects: apathy, hunger, dry mouth, tiredness, constipation, excessive daytime sleepiness (somnolence)

Dec 21, 2010 (Started Dec 21, 2010)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (hunger, tiredness, dry mouth, apathy, excessive daytime sleepiness (somnolence))
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: Daily
Advice & Tips: The impact was definitely noticeable for me. major side effect was constipation, which eventually caused me to search for other solutions
Cost: < $25 monthly
Side effects: apathy, hunger, dry mouth, tiredness, constipation, excessive daytime sleepiness (somnolence)

Oct 14, 2010 (Started Dec 21, 2010)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (hunger, tiredness, dry mouth, apathy, excessive daytime sleepiness (somnolence))
  • Adherence
    Always
  • Burden
    A little hard to take
Advice & Tips: I have dysthymia, and alot of other drugs didn't work for me - but this was. after about 3 weeks I started to feel the full effect. small side effects - dry mouth felling, and a bit of more tiredness
Cost: < $25 monthly
Side effects: apathy, hunger, dry mouth, tiredness, constipation, excessive daytime sleepiness (somnolence)

  • 0 helpful marks

Dec 22, 2008 (Started Jul 20, 2007)

  • Effectiveness
    Slight (for obsessive thinking)
  • Side effects
    Moderate (dry mouth)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 250 mg Daily
Side effects: dry mouth

  • 0 helpful marks

May 31, 1999 (Started May 15, 1999)

  • Effectiveness
    None (for chronic pain)
  • Effectiveness
    None (for pain)
  • Side effects
    Moderate (dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Clomipramine