What is Clomipramine?

Category: Prescription Drugs

Most popular types: Anafranil

false

See also: Anafranil

A tricyclic antidepressant used to treat people with obsessive-compulsive disorder (OCD). It is also used in the treatment of depression, panic attacks and pain.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
OCD (Obsessive-Compulsive Disorder) 40 20
Depressed mood 22 14
Obsessive thoughts 13 7
Major Depressive Disorder 9 4
Chronic pain 3 2
Generalized Anxiety Disorder 2 1

Show all 31 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 8
Moderate 18
Mild 12
None 9

Commonly reported side effects and conditions associated with Clomipramine

Side effect Patients
Dry mouth 10
Weight gain 5
Constipation 2
Excessive daytime sleepiness (somnolence) 2
Overwhelming fatigue 2
Sex drive (libido) decreased 2

Show all 40 reported side effects

Dosages

Based on patients currently taking Clomipramine

Dosage Patients
25 mg daily 3
50 mg daily 3
150 mg daily 3
100 mg every other week 1
75 mg daily 1
100 mg daily 1
75 mg three times daily 1

Why patients stopped taking Clomipramine

Multiple reasons could be selected

Reason Patients
Did not seem to work 20
Side effects too severe 19
Doctor's advice 14
Other 8
Personal research 3
Change in health plan coverage 1
Course of treatment ended 1
Expense 1
See all 45 patients who’ve stopped taking Clomipramine

Duration

Currently taking Clomipramine

Duration Patients
Less than 1 month 1
1 - 6 months 2
6 months - 1 year 1
1 - 2 years 2
2 - 5 years 2
5 - 10 years 3
10 years or more 3

Stopped taking Clomipramine

Duration Patients
Less than 1 month 7
1 - 6 months 6
6 months - 1 year 7
1 - 2 years 7
2 - 5 years 15
5 - 10 years 1
10 years or more 2
Adherence
Adherence Evaluations
Always 38
Usually 6
Sometimes 0
Never taken as prescribed 3
Burden
Burden Evaluations
Very hard to take 3
Somewhat hard to take 6
A little hard to take 8
Not at all hard to take 30
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 0
$50-99 2
$25-49 2
< $25 15
Not specified 27

What people switch to and from

Patients started taking Clomipramine after stopping:

Treatment Patients
Duloxetine (Cymbalta) 2
Fluoxetine (Prozac) 2
Alprazolam (Xanax) 1
Bromazepam (Lexotanil) 1
Citalopram (Celexa) 1

Show all 14 treatments patients report switching from

Patients stopped taking Clomipramine and switched to:

Treatment Patients
Sertraline (Zoloft) 2
Bupropion (Wellbutrin XL) 1
Duloxetine (Cymbalta) 1
Fluoxetine (Prozac) 1
Fluvoxamine (Luvox) 1

Show all 11 treatments patients report switching to

Last updated:

3 patient evaluations for Clomipramine

39 members have decided to share their profiles only with other members of PatientsLikeMe.

knight2
Portrait default thumb
knight2
Gender: M
Data Quality: 1 star
Depression: 0
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: Moderate
36 M
Function: High
Distress: Low
I am: g
I have:
Persistent depressive disorder (dysthymia)

See knight2's full Clomipramine history

Apr 15, 2012 (Started Dec 21, 2010)

  • Effectiveness
    Slight (for Depressed mood)
  • Side effects
    Mild (Hunger, Tiredness, Dry mouth, Apathy, Excessive daytime sleepiness (somnolence), Constipation)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: As needed
Cost: < $25 monthly
Side effects: Apathy, Hunger, Dry mouth, Tiredness, Constipation, Excessive daytime sleepiness (somnolence)

Dec 21, 2010 (Started Dec 21, 2010)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Moderate (Hunger, Tiredness, Dry mouth, Apathy, Excessive daytime sleepiness (somnolence))
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: Daily
Advice & Tips: The impact was definitely noticeable for me. major side effect was constipation, which eventually caused me to search for other solutions
Cost: < $25 monthly
Side effects: Apathy, Hunger, Dry mouth, Tiredness, Constipation, Excessive daytime sleepiness (somnolence)

Oct 14, 2010 (Started Dec 21, 2010)

  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild (Hunger, Tiredness, Dry mouth, Apathy, Excessive daytime sleepiness (somnolence))
  • Adherence
    Always
  • Burden
    A little hard to take
Advice & Tips: I have dysthymia, and alot of other drugs didn't work for me - but this was. after about 3 weeks I started to feel the full effect. small side effects - dry mouth felling, and a bit of more tiredness
Cost: < $25 monthly
Side effects: Apathy, Hunger, Dry mouth, Tiredness, Constipation, Excessive daytime sleepiness (somnolence)

  • 0 helpful marks
Mazin Z
13989 thumb
Mazin Z
Gender: M
Data Quality: 1 star
Depression: 1
Mania: 0
Emotional: 1
Anxiety: 0
Compulsion: 1
External Stress: Moderate
45 M
Function: High
Distress: Low
I am: g
I have:
OCD

See Mazin Z's full Clomipramine history

Dec 22, 2008 (Started Jul 20, 2007)

  • Effectiveness
    Slight (for Obsessive thoughts)
  • Side effects
    Moderate (Dry mouth)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 250 mg Daily
Side effects: Dry mouth

  • 0 helpful marks
steack2
30232 thumb
steack2
Gender: M
Data Quality: 1 star
Depression: 2
Mania: 1
Emotional: 2
Anxiety: 2
Compulsion: 1
External Stress: Severe
44 M
Function: Moderate
Distress: Moderate
I am: vb
I have:
GAD

See steack2's full Clomipramine history

May 31, 1999 (Started May 15, 1999)

  • Effectiveness
    None (for Chronic pain)
  • Effectiveness
    None (for Pain)
  • Side effects
    Moderate (Dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Clomipramine