What is Clozapine?

Category: Prescription Drugs

Most popular types: Clozaril Leponex

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Clozapine is an anti-psychotic medication that works by blocking receptors in the brain for several neurotransmitters. Because of concern for the side effect of agranulocytosis, clozapine is reserved for patients who have not responded to other medications.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Psychosis disorder 7 2
Schizoaffective disorder 4 1
Bipolar disorder 2 1
Bipolar I disorder 2 0
Visual hallucinations 2 0
Anxious mood 1 0

Show all 18 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
1
Moderate
4
Mild
1
None
2

Commonly reported side effects and conditions associated with Clozapine

Side effect Patients
Weight gain 3
Drowsiness 1
Overeating 1
Sleepiness 1

Dosages

Based on patients currently taking Clozapine

Dosage Patients
25 mg daily 1
50 mg daily 1
100 mg daily 1
150 mg daily 1
200 mg daily 1

Why patients stopped taking Clozapine

Multiple reasons could be selected

Reason Patients
Other 4
Did not seem to work 3
Side effects too severe 2
See all 7 patients who've stopped taking Clozapine

Duration

Currently taking Clozapine

Duration Patients
6 months - 1 year 1
1 - 2 years 3
5 - 10 years 1

Stopped taking Clozapine

Duration Patients
Less than 1 month 1
1 - 6 months 1
6 months - 1 year 2
2 - 5 years 3
Adherence
Adherence Evaluations
Always 4
Usually 2
Sometimes 1
Never taken as prescribed 1
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 2
A little hard to take 2
Not at all hard to take 4
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 1
$25-49 0
< $25 2
Not specified 5

What people switch to and from

Patients started taking Clozapine after stopping:

Treatment Patients
Quetiapine (Seroquel) 2
Ziprasidone (Geodon) 2
Lamotrigine (Lamictal) 1
Lithium Carbonate (Lithium Carbonate ER) 1
Lurasidone (Latuda) 1

Show all 6 treatments patients report switching from

Patients stopped taking Clozapine and switched to:

Treatment Patients
Hydrocodone-Acetaminophen (Norco) 1
Lithium Carbonate (Lithium Carbonate ER) 1
Last updated:

2 patient evaluations for Clozapine

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for suicidal ideation)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 25 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Slight (for suicidal ideation)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 25 mg Daily

May 11, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Major (for suicidal ideation)
  • Side effects
    Moderate
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 25 mg Daily

  • 0 helpful marks

Jul 1, 2009 (Started Jul 01, 2005)

  • Effectiveness
    Slight (for Prevent migraine)
  • Side effects
    Mild (sleepiness)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily

  • 0 helpful marks
Last updated:
Showing 2 of 2 patient evaluations for Clozapine