What is Parnate?

Category: Prescription Drugs

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Generic name: Tranylcypromine

Parnate® is a brand name for tranycypromine, a monoamine oxidase (MAO) inhibitor antidepressant. It is used in the treatment of major depressive episodes without melancholia. It may also be used for post-traumatic stress disorder (PTSD).

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 15 8
Major depressive disorder 12 2
Anxious mood 6 6
Bipolar disorder 2 2
Obsessive-compulsive disorder 2 4
Anergic depression 1 0

Show all 12 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 7
Moderate 9
Mild 7
None 1

Commonly reported side effects and conditions associated with Parnate

Side effect Patients
Excessive daytime sleepiness (somnolence) 3
Insomnia 3
Insomnia 2
Sedation 2
Buzzing electric sensation 1
Chest tightness 1

Show all 19 reported side effects

Dosages

Based on patients currently taking Parnate

Dosage Patients
30 mg daily 2
20 mg daily 1
40 mg daily 1
30 mg twice daily 1

Why patients stopped taking Parnate

Multiple reasons could be selected

Reason Patients
Did not seem to work 6
Side effects too severe 4
Other 3
Doctor's advice 2
Course of treatment ended 1
See all 10 patients who've stopped taking Parnate

Duration

Currently taking Parnate

Duration Patients
1 - 2 years 1
2 - 5 years 2
5 - 10 years 2

Stopped taking Parnate

Duration Patients
Less than 1 month 2
1 - 6 months 2
6 months - 1 year 4
2 - 5 years 1
5 - 10 years 1
Adherence
Adherence Evaluations
Always 22
Usually 2
Sometimes 0
Never taken as prescribed 0
Burden
Burden Evaluations
Very hard to take 2
Somewhat hard to take 9
A little hard to take 7
Not at all hard to take 6
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 0
$25-49 1
< $25 5
Not specified 18

What people switch to and from

Patients started taking Parnate after stopping:

Treatment Patients
Selegiline (Zelapar) 2
Clomipramine (Anafranil) 1
Dextroamphetamine (Dexedrine) 1
Gabapentin (Neurontin) 1
Lamotrigine (Lamictal) 1

Show all 7 treatments patients report switching from

Patients stopped taking Parnate and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 1
Phenelzine (Nardil) 1
Last updated:

5 patient evaluations for Parnate

May 2, 2011 (Started Nov 20, 2010)

  • Effectiveness
    None (for depressed mood)
  • Side effects
    Severe (insomnia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: After coming off this medication realized I was suffering from constant insomnia as a side effect. Also slow withdrawal still resulted in hallucinations and paranoia which are slowly dissipating. Klonopin has been helping the withdrawal symptoms.
Cost: < $25 monthly
Side effects: insomnia

  • 0 helpful marks

Jul 1, 2010 (Started Oct 14, 2009)

  • Effectiveness
    Moderate (for obsessive-compulsive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 35 mg Daily
Advice & Tips: food restrictions get irritating after a while, postural hypotension can significantly impair physical mobility, but it still makes a large reduction in symptoms, - probably will start taking again
Cost: < $25 monthly

Mar 26, 2010 (Started Oct 14, 2009)

  • Effectiveness
    Moderate (for obsessive-compulsive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: MAOI diet/food restrictions = extremely EASY to follow. not a problem.
Cost: < $25 monthly

  • 0 helpful marks

Dec 15, 2008 (Started Nov 07, 2008)

  • Effectiveness
    None (for Other)
  • Side effects
    Severe (migraine headaches, dietary restrictions, chills, tremor in legs, tremor in hands, excessive daytime sleepiness (somnolence), sexual dysfunction, constipation, insomnia)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 10 mg Daily
Side effects: chills, constipation, sexual dysfunction, insomnia, tremor in hands, tremor in legs, excessive daytime sleepiness (somnolence), tremor in hands, tremor in legs, dietary restrictions, migraine headaches

Dec 10, 2008 (Started Nov 07, 2008)

  • Effectiveness
    None (for Other)
  • Side effects
    Severe (migraine headaches, dietary restrictions, chills, tremor in legs, tremor in hands, sexual dysfunction, constipation, insomnia)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 30 mg Daily
Side effects: chills, constipation, sexual dysfunction, insomnia, tremor in hands, tremor in legs, excessive daytime sleepiness (somnolence), tremor in hands, tremor in legs, dietary restrictions, migraine headaches

Nov 29, 2008 (Started Nov 07, 2008)

  • Effectiveness
    None (for Other)
  • Side effects
    Moderate (migraine headaches, dietary restrictions, chills, sexual dysfunction, constipation, insomnia)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 30 mg Daily
Side effects: chills, constipation, sexual dysfunction, insomnia, tremor in hands, tremor in legs, excessive daytime sleepiness (somnolence), tremor in hands, tremor in legs, dietary restrictions, migraine headaches

Nov 25, 2008 (Started Nov 07, 2008)

  • Effectiveness
    None (for Other)
  • Side effects
    Severe (migraine headaches, dietary restrictions, chills, sexual dysfunction, constipation, insomnia)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 30 mg Daily
Side effects: chills, constipation, sexual dysfunction, insomnia, tremor in hands, tremor in legs, excessive daytime sleepiness (somnolence), tremor in hands, tremor in legs, dietary restrictions, migraine headaches

Nov 23, 2008 (Started Nov 07, 2008)

  • Effectiveness
    None (for Other)
  • Side effects
    Moderate (dietary restrictions, sexual dysfunction, constipation)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 30 mg Daily
Side effects: chills, constipation, sexual dysfunction, insomnia, tremor in hands, tremor in legs, excessive daytime sleepiness (somnolence), tremor in hands, tremor in legs, dietary restrictions, migraine headaches

Nov 17, 2008 (Started Nov 07, 2008)

  • Effectiveness
    None (for Other)
  • Side effects
    Mild (dietary restrictions)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 30 mg Daily
Side effects: chills, constipation, sexual dysfunction, insomnia, tremor in hands, tremor in legs, excessive daytime sleepiness (somnolence), tremor in hands, tremor in legs, dietary restrictions, migraine headaches

Nov 14, 2008 (Started Nov 07, 2008)

  • Effectiveness
    None (for Other)
  • Side effects
    Mild (dietary restrictions)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 30 mg Daily
Side effects: chills, constipation, sexual dysfunction, insomnia, tremor in hands, tremor in legs, excessive daytime sleepiness (somnolence), tremor in hands, tremor in legs, dietary restrictions, migraine headaches

Nov 13, 2008 (Started Nov 07, 2008)

  • Effectiveness
    None (for Other)
  • Side effects
    Mild (dietary restrictions)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 30 mg Daily
Side effects: chills, constipation, sexual dysfunction, insomnia, tremor in hands, tremor in legs, excessive daytime sleepiness (somnolence), tremor in hands, tremor in legs, dietary restrictions, migraine headaches

Nov 9, 2008 (Started Nov 07, 2008)

  • Effectiveness
    None (for Other)
  • Side effects
    Moderate (dietary restrictions)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 30 mg Daily
Side effects: chills, constipation, sexual dysfunction, insomnia, tremor in hands, tremor in legs, excessive daytime sleepiness (somnolence), tremor in hands, tremor in legs, dietary restrictions, migraine headaches

  • 0 helpful marks
Last updated:
Showing 3 of 5 patient evaluations for Parnate