What is Dihydroergotamine?

Category: Prescription Drugs

Most popular types: Migranal DHE 45 Injectable D.H.E. 45

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Dihydroergotamine is an antimigrane medication used for the treatment of migraine or cluster headaches with or without aura.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Migraine headaches 50 22
Migraine 11 6
Cluster headaches 5 5
Chronic headache disorder 2 1
Cluster headaches 1 0
Headaches 1 0

Show all 8 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 3
Moderate 8
Mild 12
None 10

Commonly reported side effects and conditions associated with Dihydroergotamine

Side effect Patients
Nausea 3
Fatigue 2
Muscle and joint pain 2
Nasal congestion 2
Post nasal drip 2
Bad taste in mouth 1

Show all 17 reported side effects

Dosages

Based on patients currently taking Dihydroergotamine

Dosage Patients
500mcg/spray as needed 3
4mg/mL as needed 2
4 mg weekly 1
1mg as needed 1
1ml as needed 1
1other as needed 1
2ml as needed 1
4mg as needed 1
60ml as needed 1

Why patients stopped taking Dihydroergotamine

Multiple reasons could be selected

Reason Patients
Did not seem to work 13
Doctor's advice 8
Course of treatment ended 4
Other 3
Side effects too severe 3
Expense 2
Personal research 1
See all 20 patients who've stopped taking Dihydroergotamine

Duration

Currently taking Dihydroergotamine

Duration Patients
1 - 2 years 1
2 - 5 years 5
5 - 10 years 4
10 years or more 2

Stopped taking Dihydroergotamine

Duration Patients
Less than 1 month 10
1 - 6 months 1
6 months - 1 year 3
1 - 2 years 2
2 - 5 years 4
Adherence
Adherence Evaluations
Always 21
Usually 6
Sometimes 5
Never taken as prescribed 1
Burden
Burden Evaluations
Very hard to take 5
Somewhat hard to take 5
A little hard to take 14
Not at all hard to take 9
Cost per month
Cost per month Evaluations
$200+ 4
$100-199 1
$50-99 2
$25-49 1
< $25 7
Not specified 18

What people switch to and from

Patients started taking Dihydroergotamine after stopping:

Treatment Patients
Sumatriptan (Imitrex) 5
Sumatriptan subcutaneous (Imitrex Statdose) 2
Ergotamine-caffeine (Cafergot) 1
Rizatriptan (Maxalt) 1
Topiramate (Topamax) 1

Patients stopped taking Dihydroergotamine and switched to:

Treatment Patients
Sumatriptan (Imitrex) 3
Divalproex sodium (Depakote) 2
Botulinum Toxin Type A (Botox) 1
Last updated:

2 patient evaluations for Dihydroergotamine

Aug 24, 2017 (Started Dec 29, 2015)

  • Effectiveness
    Moderate (for migraine headaches)
  • Side effects
    Moderate (nausea)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: As needed
Cost: < $25 monthly

Aug 30, 2016 (Started Dec 29, 2015)

  • Effectiveness
    Major (for migraine headaches)
  • Side effects
    Mild (nausea)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: As needed
Advice & Tips: The cost of this drug before insurance is almost $5000!!! This is for an 8 pack of the meds. My insurance brought it down to a $150 copayment, but there is a coupon available that drops it down to $35 copayment for brand and $0 for generic. The link for the 2016 coupon is: http://www.rxpharmacycoupons.com/migranal-manufacturer-coupon.html

  • 0 helpful marks

Jul 13, 2011 (Started Jul 06, 2011)

  • Effectiveness
    None (for migraine)
  • Side effects
    Mild (bad taste in mouth)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: As needed
Advice & Tips: Not helpful for all types of headaches.
Side effects: bad taste in mouth

Jul 6, 2011 (Started Jul 06, 2011)

  • Effectiveness
    Slight (for migraine)
  • Side effects
    Mild (bad taste in mouth)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: As needed
Advice & Tips: This medication helped VERY little if at all! The side effects of the horrible taste in my mouth and the lake of efficacy made it not worth it! There are so many things that could be causing the head ache. I believe mine is caused by a virus. So until I can eradicate the cause, unfortunately, the Head ache will remain and is barely manageable. I have had some relief with homeopathic headache medicine!
Side effects: bad taste in mouth

  • 0 helpful marks
Last updated:
Showing 2 of 2 patient evaluations for Dihydroergotamine