What is Pramipexole?

Category: Prescription Drugs

Most popular types: Mirapex Mirapex ER Sifrol Show all

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Pramipexole is an anti-Parkinson's agent that is used to treat symptoms of Parkinson's Disease, such as stiffness, tremors, muscle spasms, and poor muscle control and for moderate to severe primary restless legs syndrome. It may also be used for the treatment of depression.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 1,078 616
Restless legs syndrome 247 117
Restless feeling in legs 181 79
Tremor(s) 50 42
Stiffness/spasticity 36 30
Periodic limb movement disorder 24 14

Show all 93 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 132
Moderate 222
Mild 205
None 305

Commonly reported side effects and conditions associated with Pramipexole

Side effect Patients
Drowsiness 87
Weight gain 51
Nausea 46
Insomnia 39
Vivid dreams 27
Excessive daytime sleepiness (somnolence) 25

Show all 238 reported side effects

Dosages

Based on patients currently taking Pramipexole

Dosage Patients
1.5 mg daily 24
0.25 mg daily 20
1 mg daily 18
0.5 mg daily 17
0.75 mg daily 17
0.125 mg daily 16
0.5 mg three times daily 14
3 mg daily 14
1 mg three times daily 13
0.25 mg three times daily 11

See all 53 dosages

Why patients stopped taking Pramipexole

Multiple reasons could be selected

Reason Patients
Side effects too severe 251
Doctor's advice 140
Did not seem to work 128
Other 54
Expense 28
Personal research 24
Change in health plan coverage 11
Course of treatment ended 10
See all 482 patients who've stopped taking Pramipexole

Duration

Currently taking Pramipexole

Duration Patients
Less than 1 month 3
1 - 6 months 9
6 months - 1 year 10
1 - 2 years 34
2 - 5 years 73
5 - 10 years 81
10 years or more 42

Stopped taking Pramipexole

Duration Patients
Less than 1 month 53
1 - 6 months 106
6 months - 1 year 81
1 - 2 years 92
2 - 5 years 114
5 - 10 years 36
10 years or more 5
Adherence
Adherence Evaluations
Always 683
Usually 129
Sometimes 17
Never taken as prescribed 35
Burden
Burden Evaluations
Very hard to take 31
Somewhat hard to take 99
A little hard to take 173
Not at all hard to take 561
Cost per month
Cost per month Evaluations
$200+ 33
$100-199 20
$50-99 53
$25-49 118
< $25 330
Not specified 310

What people switch to and from

Patients started taking Pramipexole after stopping:

Treatment Patients
Ropinirole (Requip) 21
Carbidopa-Levodopa (Sinemet) 12
Rotigotine (Neupro Patch) 11
Rasagiline (Azilect) 7
Amantadine (Symmetrel) 4

Show all 15 treatments patients report switching from

Patients stopped taking Pramipexole and switched to:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 22
Ropinirole (Requip) 17
Rotigotine (Neupro Patch) 10
Amantadine (Symmetrel) 6
Carbidopa-Entacapone-Levodopa (Stalevo) 3

Show all 18 treatments patients report switching to

Last updated:

90 patient evaluations for Pramipexole

Nov 4, 2017 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (gambling urges, nausea and vomiting)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 0.5 mg Four times daily
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Aug 10, 2017 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (gambling urges, nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.5 mg Four times daily
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

May 25, 2017 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (gambling urges, nausea and vomiting)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 0.5 mg Four times daily
Advice & Tips: Eat crackers when taking it to help with nausea
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Jan 17, 2017 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (gambling urges, nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.5 mg Four times daily
Advice & Tips: Eat crackers before taking the drug
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Oct 10, 2016 (Started Oct 01, 2004)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.5 mg Four times daily
Advice & Tips: No problems
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Sep 14, 2016 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (gambling urges, nausea and vomiting)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 0.5 mg Four times daily
Advice & Tips: Eat crackers.
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Jul 10, 2016 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 0.5 mg Four times daily
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Sep 16, 2015 (Started Oct 01, 2004)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Moderate (gambling urges, nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.5 mg Four times daily
Advice & Tips: Eat crackers when taking it to help with nausea
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Jan 24, 2011 (Started Oct 01, 2004)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Severe (gambling urges, nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3.5 mg Daily
Advice & Tips: Severly vomiting. Stopped the drug.
Cost: < $25 monthly
Side effects: gambling urges, nausea and vomiting

Aug 26, 2008 (Started Oct 01, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (gambling urges)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 1.5 mg Daily
Advice & Tips: Good medicine for Parkinsons, but can make you want to gamble.
Cost: $25-49 monthly
Side effects: gambling urges, nausea and vomiting

  • 0 helpful marks

Aug 24, 2017 (Started Jan 15, 2012)

  • Effectiveness
    Major (for restless legs syndrome)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.75 mg Daily

Aug 27, 2016 (Started Jan 15, 2012)

  • Effectiveness
    Major (for restless legs syndrome)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.75 mg Daily

  • 0 helpful marks

Jun 13, 2017 (Started Jul 01, 2003)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 0.125 mg Five times daily
Cost: < $25 monthly

Apr 14, 2016 (Started Jul 01, 2003)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1 mg Daily
Advice & Tips: do not suddenly go on or off this med. Though I have not had issues, many people do with sudden large increases/decreases. Otherwise it works well for me in conjunction with Carbidopa/levodopa.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 90 patient evaluations for Pramipexole