What is Paliperidone?

Category: Prescription Drugs

Most popular types: Invega Invega Sustenna Xeplion

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Paliperidone is an atypical antipsychotic agent used in the treatment of schizophrenia. It is being used off-label for psychosis and agitation related to Alzheimer's dementia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Schizoaffective Disorder 24 18
Bipolar rapid cycling 15 11
Psychosis Disorder 14 6
Bipolar I Disorder 5 5
Bipolar Disorder 4 2
Bipolar II Disorder 3 2

Show all 32 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 13
Moderate 19
Mild 14
None 7

Commonly reported side effects and conditions associated with Paliperidone

Side effect Patients
Weight gain 13
Lactation 4
Drowsiness 3
Sexual dysfunction 3
Dizziness and feeling faint 2
Hyperprolactinemia 2

Show all 51 reported side effects

Dosages

Based on patients currently taking Paliperidone

Dosage Patients
3 mg daily 4
156 mg monthly 2
6 mg daily 2
9 mg daily 2
1 other monthly 1
100 mg monthly 1
150 mg monthly 1
170 mg monthly 1
3 mg twice daily 1
544 mg every 3 months 1

See all 20 dosages

Why patients stopped taking Paliperidone

Multiple reasons could be selected

Reason Patients
Side effects too severe 21
Doctor's advice 16
Did not seem to work 14
Other 8
Personal research 6
Expense 2
Course of treatment ended 1
See all 38 patients who’ve stopped taking Paliperidone

Duration

Currently taking Paliperidone

Duration Patients
Less than 1 month 1
1 - 6 months 4
6 months - 1 year 4
1 - 2 years 4
2 - 5 years 8
5 - 10 years 4

Stopped taking Paliperidone

Duration Patients
Less than 1 month 10
1 - 6 months 15
6 months - 1 year 4
1 - 2 years 3
2 - 5 years 4
5 - 10 years 2
10 years or more 1
Adherence
Adherence Evaluations
Always 44
Usually 6
Sometimes 2
Never taken as prescribed 1
Burden
Burden Evaluations
Very hard to take 5
Somewhat hard to take 6
A little hard to take 12
Not at all hard to take 30
Cost per month
Cost per month Evaluations
$200+ 2
$100-199 0
$50-99 2
$25-49 2
< $25 28
Not specified 19

What people switch to and from

Patients started taking Paliperidone after stopping:

Treatment Patients
Risperidone (Risperdal) 6
Aripiprazole (Abilify) 3
Lithium Carbonate (Lithium Carbonate ER) 3
Quetiapine (Seroquel) 3
Haloperidol (Haldol) 2

Show all 13 treatments patients report switching from

Patients stopped taking Paliperidone and switched to:

Treatment Patients
Lurasidone (Latuda) 5
Aripiprazole (Abilify) 2
Paliperidone (Invega) 2
asenapine (Saphris) 1
Brexpiprazole (Rexulti) 1

Show all 8 treatments patients report switching to

Last updated:

4 patient evaluations for Paliperidone

44 members have decided to share their profiles only with other members of PatientsLikeMe.

CupcakeKitten
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CupcakeKitten
Gender: F
Data Quality: 3 stars
Depression: 2
Mania: 0
Emotional: 2
Anxiety: 1
Compulsion: 1
External Stress: Moderate
25 F
Function: Moderate
Distress: Low
I am: g
I have:
Borderline Personality

See CupcakeKitten's full Paliperidone history

Jul 18, 2016 (Started Jun 30, 2016)

  • Effectiveness
    Slight (for Self injury or harm)
  • Effectiveness
    Slight (for Dissociation)
  • Effectiveness
    Slight (for Depersonalization-derealization)
  • Side effects
    Mild (Drowsiness)
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 3 mg Daily
Cost: < $25 monthly

Jul 5, 2016 (Started Jun 30, 2016)

  • Effectiveness
    Slight (for Self injury or harm)
  • Effectiveness
    Moderate (for Dissociation)
  • Effectiveness
    Moderate (for Depersonalization-derealization)
  • Side effects
    Moderate (Drowsiness)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 3 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
AutumnFairy
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AutumnFairy
Gender: F
Data Quality: 1 star
Pain: All
Fatigue: Most
Sleep: Some
Stiffness: All
function: Little
external_stress: Some
Stickman: most
Description:F46y
FM:10y Dx
CFS:?y
I am: vb
I have:
Fibromyalgia

See AutumnFairy's full Paliperidone history

Jul 13, 2011 (Started Mar 14, 2011)

  • Effectiveness
    Slight (for Depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 mg Daily
Advice & Tips: possible weight gain
Cost: < $25 monthly

  • 0 helpful marks
AutumnFairy
71972 thumb
AutumnFairy
Gender: F
Data Quality: 1 star
Pain: All
Fatigue: Most
Sleep: Some
Stiffness: All
function: Little
external_stress: Some
Stickman: most
Description:F46y
FM:10y Dx
CFS:?y
I am: vb
I have:
Fibromyalgia

See AutumnFairy's full Paliperidone history

Mar 21, 2011 (Started Jun 01, 2010)

  • Effectiveness
    None (for Depressed mood)
  • Side effects
    Severe (Weight gain)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 6 mg Daily
Advice & Tips: I felt no difference when I took this medication. I did notice the weight gain, though, and ultimately quit taking it.
Cost: < $25 monthly
Side effects: Weight gain

Jan 16, 2011 (Started Jun 01, 2010)

  • Effectiveness
    Can’t tell (for Depressed mood)
  • Side effects
    Severe (Weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg Daily
Advice & Tips: I have quit taking Invega after gaining 40 pounds. I can't stand the weight any longer. I am anorexic, so that's a big deal to me.
Cost: < $25 monthly
Side effects: Weight gain

  • 0 helpful marks
Last updated:
Showing 3 of 4 patient evaluations for Paliperidone