What is Paliperidone?

Category: Prescription Drugs

Most popular types: Invega Invega Sustenna Xeplion

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Paliperidone is an atypical antipsychotic agent used in the treatment of schizophrenia. It may also be used for psychosis and agitation related to Alzheimer's dementia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
schizoaffective disorder 28 21
psychosis disorder 16 7
Bipolar rapid cycling 15 11
bipolar I disorder 5 5
bipolar disorder 4 2
bipolar II disorder 4 3

Show all 34 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 13
Moderate 19
Mild 14
None 12

Commonly reported side effects and conditions associated with Paliperidone

Side effect Patients
Weight gain 13
Lactation 4
Drowsiness 3
Sexual dysfunction 3
Dizziness and feeling faint 2
hyperprolactinemia 2

Show all 51 reported side effects

Dosages

Based on patients currently taking Paliperidone

Dosage Patients
156 mg monthly 5
3 mg daily 4
6 mg daily 2
9 mg daily 2
12 mg daily 2
1 other monthly 1
50 mg every 3 weeks 1
100 mg monthly 1
117 mg monthly 1
150 mg monthly 1

See all 19 dosages

Why patients stopped taking Paliperidone

Multiple reasons could be selected

Reason Patients
Side effects too severe 21
Doctor's advice 17
Did not seem to work 14
Other 8
Personal research 6
Expense 2
Course of treatment ended 1
See all 39 patients who've stopped taking Paliperidone

Duration

Currently taking Paliperidone

Duration Patients
1 - 6 months 7
6 months - 1 year 6
1 - 2 years 4
2 - 5 years 8
5 - 10 years 5

Stopped taking Paliperidone

Duration Patients
Less than 1 month 10
1 - 6 months 15
6 months - 1 year 5
1 - 2 years 3
2 - 5 years 4
5 - 10 years 2
10 years or more 1
Adherence
Adherence Evaluations
Always 48
Usually 7
Sometimes 2
Never taken as prescribed 1
Burden
Burden Evaluations
Very hard to take 5
Somewhat hard to take 6
A little hard to take 13
Not at all hard to take 34
Cost per month
Cost per month Evaluations
$200+ 3
$100-199 0
$50-99 2
$25-49 2
< $25 30
Not specified 21

What people switch to and from

Patients started taking Paliperidone after stopping:

Treatment Patients
Risperidone (Risperdal) 6
Quetiapine (Seroquel) 4
Aripiprazole (Abilify) 3
Haloperidol (Haldol) 3
Lithium Carbonate (Lithium Carbonate ER) 3

Show all 14 treatments patients report switching from

Patients stopped taking Paliperidone and switched to:

Treatment Patients
Lurasidone (Latuda) 5
Aripiprazole (Abilify) 2
Paliperidone (Invega) 2
asenapine (Saphris) 1
Brexpiprazole (Rexulti) 1

Show all 8 treatments patients report switching to

Last updated:

6 patient evaluations for Paliperidone

TheWorshipper
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TheWorshipper
Gender: M
Data Quality: 3 stars
Depression: 1
Mania: 1
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: Low
59 M
Function: High
Distress: Low
I am: n
I have:
schizoaffective disorder

See TheWorshipper's full Paliperidone history

May 29, 2017 (Started Apr 21, 2017)

  • Effectiveness
    Major (for Wishing for death)
  • Effectiveness
    Major (for schizoaffective disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 12 mg Daily
Advice & Tips: I was experiencing periods of torment. It was like if a BLACK HOLE was sucking my mind DRY, LIQUID ACID to my sou, HELL, my mind would collapses, and I was unable to function as usual. These periods would last only a few minutes or can last up to as long as several hours and happen quite regularly and had been going on for about the last 40 years, until I started Invega. Also I was wishing for death pretty BAD before taking Invega, but now I don't and these periods of torment have ended. When not on any antipsychotic medications, including Invega, I feel like; others could hear my thoughts (broadcasting), that I could hear other people thoughts (mind reading), that I could communicate by thought with others without speaking a word (telepathic communication), not only could I communicate with other people in this way but I could communicate with other things as if they had human like qualities (anthropomorphic telepathic communication), believing that I am super important to the world (grandiose thinking), that others were out to kill me (paranoia), and I would become very delusional. But, now after taking the antipsychotic medications for some time, not only do I not believe in these things (powers) were never true for me, I also believe that no one else has these powers. Maybe some people may have others out to kill them, but this is not true for me. Also, for over 35 years (1977 - 2013) I believed that God would talk to me personally and would give me personal instructions, but now, I don't believe this is/was probably ever true. Now, I believe God gave me a brain/mind so that I could figure out how to love other, which is what He wants me to do. Relief of the psychotic symptoms comes with a price, the side effects of those antipsychotic medications. The antipsychotic medications of today, work better with less side effects. than those in 1977 when I started taking them. I have no sex drives (libido), an involuntary movements of the tongue and lips (tardive dyskinesia), and an internal restlessness (akathisia), which I had before starting Invega, so I can’t blame Invega for them.
Cost: < $25 monthly

May 17, 2017 (Started Apr 21, 2017)

  • Effectiveness
    Major (for Wishing for death)
  • Effectiveness
    Major (for schizoaffective disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 12 mg Daily
Advice & Tips: I was wishing for death pretty BAD before taking Invega, but now I don't. When not on any antipsychotic medications, I feel like; others could hear my thoughts (broadcasting), that I could hear other people thoughts (mind reading), that I could communicate by thought with others without speaking a word (telepathic communication), not only could I communicate with other people in this way but I could communicate with other things as if they had human like qualities (anthropomorphic telepathic communication), believing that I am super important to the world (grandiose thinking), that others were out to kill me (paranoia), and I would become very delusional. But, now after taking the antipsychotic medications for some time, not only do I not believe in these things (powers) were never true for me, I also believe that no one else has these powers. Maybe some people may have others out to kill them, but this is not true for me. Also, for over 35 years (1977 - 2013) I believed that God would talk to me personally and would give me personal instructions, but now, I don't believe this is/was probably ever true. Now, I believe God gave me a brain/mind so that I could figure out how to love other, which is what He wants me to do. Relief of the psychotic symptoms comes with a price, the side effects of those antipsychotic medications. The antipsychotic medications of today, work better with less side effects. than those in 1977 when I started taking them. I have no sex drives (libido), an involuntary movements of the tongue and lips (tardive dyskinesia), and an internal restlessness (akathisia), which I had before starting Invega, so I can’t blame Invega for them.
Cost: < $25 monthly

  • 0 helpful marks
one_step_closer
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one_step_closer
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 1
Compulsion: 0
External Stress: Low
30 F
Function: High
Distress: Low
I am: b
I have:
borderline personality disorder

See one_step_closer's full Paliperidone history

Apr 24, 2017 (Started Sep 05, 2016)

  • Effectiveness
    Can’t tell (for borderline personality disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Monthly

  • 0 helpful marks
CupcakeKitten
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CupcakeKitten
Gender: F
Data Quality: 2 stars
Depression: 1
Mania: 0
Emotional: 2
Anxiety: 1
Compulsion: 0
External Stress: Severe
25 F
Function: Moderate
Distress: Low
I am: g
I have:
Borderline Personality

See CupcakeKitten's full Paliperidone history

Jul 18, 2016 (Started Jun 30, 2016)

  • Effectiveness
    Slight (for Self injury or harm)
  • Effectiveness
    Slight (for Dissociation)
  • Effectiveness
    Slight (for Depersonalization-derealization)
  • Side effects
    Mild (Drowsiness)
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 3 mg Daily
Cost: < $25 monthly

Jul 5, 2016 (Started Jun 30, 2016)

  • Effectiveness
    Slight (for Self injury or harm)
  • Effectiveness
    Moderate (for Dissociation)
  • Effectiveness
    Moderate (for Depersonalization-derealization)
  • Side effects
    Moderate (Drowsiness)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 3 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 6 patient evaluations for Paliperidone